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1. Full Text Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome
by Wei, Chun-Yu, MS and Chung, Wen-Hung, MD, PhD and Huang, Hsiao-Wen, MS and Chen, Yuan-Tsong, MD, PhD and Hung, Shuen-Iu, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2012, Volume 129, Issue 6, pp. 1562 - 1569.e5
Allergy and Immunology | Stevens-Johnson syndrome | HLA | drug hypersensitivity | Carbamazepine | toxic epidermal necrolysis | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Dermatology | Bullous diseases of the skin | Biological and medical sciences | Medical sciences | Stevens-Johnson Syndrome - immunology | HLA-B15 Antigen - chemistry | Humans | Middle Aged | Male | Young Adult | Carbamazepine - chemistry | Stevens-Johnson Syndrome - chemically induced | Lymphocyte Activation - immunology | HLA-B15 Antigen - genetics | Drug Hypersensitivity - genetics | Adult | Female | Child | T-Lymphocytes, Cytotoxic - immunology | Cell Line | Peptides - immunology | Models, Molecular | Carbamazepine - immunology | Antigen Presentation - immunology | Protein Binding - immunology | Stevens-Johnson Syndrome - genetics | Carbamazepine - adverse effects | Drug Hypersensitivity - immunology | Adolescent | HLA-B15 Antigen - metabolism | T-Lymphocytes - immunology | Aged | Medical colleges | Care and treatment | Anticonvulsants | Histocompatibility antigens | Lymphocytes | HLA histocompatibility antigens | Universities and colleges | T cells | Index Medicus | Abridged Index Medicus | Drugs | Hypersensitivity | Antigen processing | Cytotoxicity | Lymphocytes T | Toxic epidermal necrolysis | Molecular modelling | surface plasmon resonance | Site-directed mutagenesis | Drug metabolism | Histocompatibility antigen HLA | Mathematical models | Antigenic determinants
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2. Full Text Identification of drug-specific public TCR driving severe cutaneous adverse reactions
by Pan, Ren-You and Chu, Mu-Tzu and Wang, Chuang-Wei and Lee, Yun-Shien and Lemonnier, Francois and Michels, Aaron W and Schutte, Ryan and Ostrov, David A and Chen, Chun-Bing and Phillips, Elizabeth Jane and Mallal, Simon Alexander and Mockenhaupt, Maja and Bellon, Teresa and Tassaneeyakul, Wichittra and White, Katie D and Roujeau, Jean-Claude and Chung, Wen-Hung and Hung, Shuen-Iu
Nature communications, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3569 - 13
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Stevens-Johnson Syndrome - immunology | Humans | Middle Aged | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Adoptive Transfer | Receptor-CD3 Complex, Antigen, T-Cell - metabolism | HLA-B15 Antigen - genetics | T-Lymphocytes, Cytotoxic - transplantation | Adult | Female | HLA-B15 Antigen - immunology | Skin - pathology | Disease Models, Animal | Skin - immunology | Severity of Illness Index | T-Lymphocytes, Cytotoxic - immunology | Mice, Transgenic | Stevens-Johnson Syndrome - diagnosis | Animals | Carbamazepine - adverse effects | T-Lymphocytes, Cytotoxic - metabolism | Aged | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Receptor-CD3 Complex, Antigen, T-Cell - immunology | Stevens-Johnson Syndrome - pathology | Phenotypes | Liver diseases | Immune response | Therapeutic applications | Hypersensitivity | Oral administration | Transgenic mice | Cytotoxicity | Lymphocytes T | Inflammation | T cell receptors | Drug development | Adoptive transfer | Carbamazepine | Mimicry | T-cell receptor | Toxic epidermal necrolysis | Side effects | Next-generation sequencing | Lymphocytes | Skin | Histocompatibility antigen HLA | Erythema | Immune system | Index Medicus
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3. Full Text Carbamazepine-Induced Toxic Effects and HLA-B1502 Screening in Taiwan
by Chen, Pei and Chen, Chien-Hsiun and Chen, Ying-Ju and Chen, Yuan-Tsong and Chen, Luke and Lin, Shu-Yi and Lin, Juei-Jueng and Lin, Yu-Hsuan and Lu, Chung-Ta and Lu, Chin-Song and Lu, Cheng-Hsien and Ong, Cheung-Ter and Hsieh, Peiyuan F and Yang, Chih-Chao and Tai, Chih-Ta and Wu, Jer-Yuarn and Wu, Shey-Lin and Hsu, Yung-Chu and Yu, Hsiang-Yu and Ro, Long-Sun and Chu, Chun-Che and Tsai, Pei-Joung and Tsai, Jing-Jane and Su, Yu-Hsiang and Lan, Sheng-Hsing and Sung, Sheng-Feng and Chuang, Hui-Ping and Huang, Li-Chen and Liao, Hung-Ting and Chung, Wen-Hung and Hung, Shuen-Iu and Chang, Chi-Feng and Shen, Chen-Yang and Taiwan SJS Consortium
The New England journal of medicine, ISSN 0028-4793, 03/2011, Volume 364, Issue 12, pp. 1126 - 1133
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | General aspects | Prevention and actions | Pharmacology. Drug treatments | Biological and medical sciences | Anticonvulsants. Antiepileptics. Antiparkinson agents | Medical sciences | Neuropharmacology | Drug-Related Side Effects and Adverse Reactions - prevention & control | Genetic Testing | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Stevens-Johnson Syndrome - prevention & control | Child, Preschool | Infant | Male | Incidence | Young Adult | Stevens-Johnson Syndrome - chemically induced | Anticonvulsants - adverse effects | Stevens-Johnson Syndrome - epidemiology | Drug-Related Side Effects and Adverse Reactions - genetics | Aged, 80 and over | Adult | Female | HLA-B15 Antigen | Child | HLA-B Antigens - genetics | Pharmacogenetics | Anticonvulsants - therapeutic use | Carbamazepine - therapeutic use | Genotype | Stevens-Johnson Syndrome - genetics | Carbamazepine - adverse effects | Adolescent | Taiwan | Aged | Taiwanese | Complications and side effects | Stevens-Johnson syndrome | Toxic epidermal necrolysis | Usage | Histocompatibility antigens | HLA histocompatibility antigens | Causes of | Medical screening | Health aspects | Carbamazepine | Testing | Confidence intervals | Medical research | Clinical medicine | Apoptosis | Index Medicus | Abridged Index Medicus
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4. Full Text Unbiased Identification of T-Cell Receptors Targeting Immunodominant Peptide–MHC Complexes for T-Cell Receptor Immunotherapy
by Lorenz, Felix K.M and Ellinger, Christian and Kieback, Elisa and Wilde, Susanne and Lietz, Maria and Schendel, Dolores J and Uckert, Wolfgang
Human gene therapy, ISSN 1043-0342, 12/2017, Volume 28, Issue 12, pp. 1158 - 1168
Research Articles | T cell receptor (TCR) discovery | MHC cell library | immunodominance | human papillomavirus ES | immunotherapy | TCR gene therapy | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | HLA-B7 Antigen - genetics | Humans | Peptides - immunology | Peptides - genetics | Neoplasms - therapy | HLA-B15 Antigen - genetics | HLA-B7 Antigen - immunology | Adoptive Transfer - methods | Neoplasms - genetics | Neoplasms - immunology | K562 Cells | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | HLA-B15 Antigen - immunology | Neoplasms - pathology | Killing | Antigens | Peptides | T cell receptors | Lymphocytes T | T-cell receptor | Receptors | Human papillomavirus | Major histocompatibility complex | Lymphocytes | Immunotherapy | Histocompatibility antigen HLA | Cancer | Index Medicus
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5. Full Text Controversies in drug allergy: Testing for delayed reactions
by Phillips, Elizabeth J and Bigliardi, Paul and Bircher, Andreas J and Broyles, Ana and Chang, Yoon-Seok and Chung, Wen-Hung and Lehloenya, Rannakoe and Mockenhaupt, Maja and Peter, Jonny and Pirmohamed, Munir and Roujeau, Jean-Claude and Shear, Neil H and Tanno, Luciana Kase and Trubiano, Jason and Valluzzi, Rocco and Barbaud, Annick
Journal of allergy and clinical immunology, ISSN 0091-6749, 01/2019, Volume 143, Issue 1, pp. 66 - 73
prick | patch | fixed drug eruption | Delayed | Stevens-Johnson syndrome/toxic epidermal necrolysis | oral challenge | drug reaction with eosinophilia and systemic symptoms | acute generalized exanthematous pustulosis | HLA | intradermal | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Stevens-Johnson Syndrome - immunology | Humans | HLA-B Antigens - immunology | Carbamazepine - therapeutic use | Skin Tests - standards | Asian Continental Ancestry Group | Stevens-Johnson Syndrome - genetics | Animals | Carbamazepine - adverse effects | HLA-B15 Antigen - genetics | Dideoxynucleosides - adverse effects | Dideoxynucleosides - therapeutic use | HLA-B15 Antigen - immunology | HLA-B Antigens - genetics | Stevens-Johnson Syndrome - pathology | Diagnosis | Drug therapy | Allergic reaction | Drug allergy | Stevens-Johnson syndrome | Hypersensitivity (delayed) | Lymphocytes T | Eruptions | Lymphocytes | Drug tolerance | Immunopathogenesis | Biocompatibility | Drug dosages | Phenotypes | Cross-reactivity | Hypersensitivity | Pustulosis | Eosinophilia | Immunological tolerance | Carbamazepine | Toxic epidermal necrolysis | Side effects | Abacavir | Skin | In vivo methods and tests | Histocompatibility antigen HLA | Diagnostic systems | Skin tests | Index Medicus | Abridged Index Medicus | Life Sciences | Allergology | Human health and pathology | Dermatology | Pharmaceutical sciences | DRESS | FDE | delayed | TEN | SJS | AGEP
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6. Full Text PharmGKB summary: very important pharmacogene information for human leukocyte antigen B
by Barbarino, Julia M and Kroetz, Deanna L and Klein, Teri E and Altman, Russ B
Pharmacogenetics and genomics, ISSN 1744-6872, 04/2015, Volume 25, Issue 4, pp. 205 - 221
Pharmacology & Pharmacy | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Genetic Variation | Pharmacogenetics | Genetic Association Studies | HLA-B Antigens - genetics | Gene Frequency | Humans | Index Medicus | HLA-B58:01 | HLA-B57:01 | Abacavir | HLA-B | allopurinol | phenytoin | HLA-B15:02 | pharmacogenetics | carbamazepine | PharmGKB
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7. Full Text Integrated whole genome and transcriptome analysis identified a therapeutic minor histocompatibility antigen in a splice variant of ITGB2
by Pont, Margot J and Van Der Lee, Dyantha I and Van Der Meijden, Edith D and Van Bergen, Cornelis A. M and Kester, Michel G. D and Honders, Maria W and Vermaat, Martijn and Eefting, Matthias and Marijt, Erik W. A and Kielbasa, Szymon M and T'Hoen, Peter A. C and Frederik Falkenburg, J.H and Griffioen, Marieke
Clinical cancer research, ISSN 1078-0432, 08/2016, Volume 22, Issue 16, pp. 4185 - 4196
Life Sciences & Biomedicine | Oncology | Science & Technology | Amino Acid Sequence | Alternative Splicing | T-Lymphocytes | Humans | Integrin beta3 - chemistry | Peptides - immunology | Peptides - genetics | Hematopoietic Stem Cell Transplantation | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Epitopes, T-Lymphocyte - genetics | Gene Expression Profiling | Transplantation, Homologous | Whole Genome Sequencing | HLA-B15 Antigen - genetics | Base Sequence | Minor Histocompatibility Antigens - genetics | Female | Integrin beta3 - genetics | Epitopes, T-Lymphocyte - immunology | HLA-B15 Antigen - immunology | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - immunology | Minor Histocompatibility Antigens - immunology | Minor Histocompatibility Antigens - chemistry | Index Medicus
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8. Full Text Specific amino acid patterns define split specificities of HLA-B15 antigens enabling conversion from DNA-based typing to serological equivalents
by Duygu, Burcu and Matern, Benedict M and Wieten, Lotte and Voorter, Christina E. M and Tilanus, Marcel G. J
Immunogenetics (New York), ISSN 0093-7711, 09/2020, Volume 72, Issue 6-7, pp. 339 - 346
ALLELES | HLA B15 serological equivalents | HLA-B15 amino acid polymorphism | LinkSeq (TM) HLA typing | HLA-B | HLA-B15 splits | BW4 | Immunology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Antigens | High resolution | Antibodies | Amino acids | Transplantation | Serology | Subgroups | Gene sequencing | Equivalence | Alleles | Histocompatibility antigen HLA | Tissue typing | Deoxyribonucleic acid--DNA | DNA sequencing | Index Medicus | LinkSēq™ HLA typing | Original
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9. HLA-B locus in Caucasian patients with carbamazepine hypersensitivity
by Alfirevic, Ana and Jorgensen, Andrea L and Williamson, Paula R and Chadwick, David W and Park, B. Kevin and Pirmohamed, Munir
Pharmacogenomics, ISSN 1462-2416, 09/2006, Volume 7, Issue 6, pp. 813 - 818
HLA-B | Pharmacogenetics | Adverse drug reactions | Epilepsy | Hypersensitivity | Carbamazepine | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | European Continental Ancestry Group - genetics | Gene Frequency | Humans | Asian Continental Ancestry Group - genetics | HLA-B7 Antigen | United Kingdom | Genetic Markers | Case-Control Studies | Carbamazepine - adverse effects | HLA-DR3 Antigen - genetics | HLA-B8 Antigen | Drug Hypersensitivity - immunology | HLA-DQ Antigens - genetics | Toxicogenetics | Alleles | Drug Hypersensitivity - genetics | HLA-B15 Antigen | HLA-B Antigens - genetics | Index Medicus
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