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Journal Article
Blood, ISSN 0006-4971, 04/2013, Volume 121, Issue 15, pp. 2975 - 2987
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous, immature myeloid cell population with the ability to suppress immune responses. MDSCs have been... 
CANCER-PATIENTS | DENDRITIC CELLS | T-REGULATORY CELLS | IMMUNOSUPPRESSION | BONE-MARROW | GROWTH | PERIPHERAL-BLOOD | DIFFERENTIATION | IDENTIFICATION | HEMATOLOGY | PROGRESSION | Cell Proliferation | Reactive Oxygen Species - metabolism | Coculture Techniques | Humans | Sialic Acid Binding Ig-like Lectin 3 - immunology | Multiple Myeloma - immunology | Thalidomide - pharmacology | Lewis X Antigen - metabolism | Lipopolysaccharides - immunology | Thalidomide - analogs & derivatives | Flow Cytometry | T-Lymphocytes - metabolism | Myeloid Cells - immunology | Reactive Oxygen Species - immunology | Myeloid Cells - drug effects | Antineoplastic Agents - pharmacology | HLA-DR Antigens - metabolism | Sialic Acid Binding Ig-like Lectin 3 - metabolism | Cytokines - immunology | Tumor Microenvironment - drug effects | Bortezomib | CD11b Antigen - immunology | Cytokines - metabolism | Cells, Cultured | Lewis X Antigen - immunology | Multiple Myeloma - metabolism | Tumor Microenvironment - immunology | Multiple Myeloma - pathology | Lipopolysaccharides - pharmacology | Cell Line, Tumor | Myeloid Cells - metabolism | T-Lymphocytes - immunology | HLA-DR Antigens - immunology | CD11b Antigen - metabolism | Pyrazines - pharmacology | Immunologic Factors - pharmacology | Boronic Acids - pharmacology | Tumor Burden - immunology | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
Journal Article
Scientific Reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, pp. 1188 - 1188
Recent reports in mice demonstrate that basophils function as antigen presenting cells (APC). They express MHC class II and co-stimulatory molecules CD80 and... 
IMMUNITY | RESPONSES | ASPERGILLUS-FUMIGATUS | PROTEASE-ACTIVATED RECEPTORS | DENDRITIC CELLS | INFLAMMATION | IGE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | NEPHRITIS | T-CELLS | Coculture Techniques | Dendritic Cells - immunology | Humans | Monocytes - metabolism | Monocytes - immunology | Recombinant Proteins - biosynthesis | CD4-Positive T-Lymphocytes - immunology | Basophils - immunology | Dendritic Cells - drug effects | HLA-DR Antigens - metabolism | Dendritic Cells - metabolism | Basophils - drug effects | Antigen-Presenting Cells - metabolism | Antigen-Presenting Cells - drug effects | CD4-Positive T-Lymphocytes - cytology | Interleukin-4 - metabolism | Allergens - genetics | B7-1 Antigen - metabolism | Recombinant Proteins - genetics | Antigens, Plant - pharmacology | Fungal Proteins - genetics | Recombinant Proteins - pharmacology | Antigen-Presenting Cells - immunology | Antigens, Plant - genetics | Allergens - metabolism | Monocytes - drug effects | B7-2 Antigen - metabolism | Antigens, Plant - metabolism | Allergens - pharmacology | Fungal Proteins - pharmacology | Basophils - metabolism | Fungal Proteins - metabolism | Cell culture | Antigens | Allergens | Bet v 1 antigen | Dendritic cells | CD86 antigen | Secretion | Immunoglobulin E | CD80 antigen | Lymphocytes T | CD4 antigen | Monocytes | Interleukin 4 | Major histocompatibility complex | Antigen-presenting cells | TLR2 protein | Toll-like receptors | Histocompatibility antigen HLA | Leukocytes (basophilic) | Index Medicus | Life Sciences | Innate immunity | Immunology
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 01/2015, Volume 96, Issue 1, pp. 136 - 146
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, pp. e27944 - e27944
Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by... 
MIGRATION | ACTIVATION | FUNCTIONAL MATURATION | ANGIOGENESIS | VEGF | MULTIDISCIPLINARY SCIENCES | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | CXC CHEMOKINES | G-CSF | T-CELLS | ENDOTHELIAL GROWTH-FACTOR | Antigens, CD - immunology | Immunoglobulins - immunology | Membrane Glycoproteins - metabolism | Chemokine CCL2 - immunology | Coculture Techniques | Dendritic Cells - immunology | Humans | Culture Media, Conditioned - pharmacology | Male | Vascular Endothelial Growth Factor A - metabolism | Chemokine CXCL5 - metabolism | Interferon-gamma - metabolism | Chemokine CXCL1 - pharmacology | Lipopolysaccharides - immunology | Antigens, CD - metabolism | Immunoglobulins - metabolism | Chemokine CXCL5 - pharmacology | Flow Cytometry | Female | Chemokine CCL2 - metabolism | Membrane Glycoproteins - immunology | B7-2 Antigen - immunology | Chemokine CXCL1 - metabolism | HLA-DR Antigens - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Colorectal Neoplasms - metabolism | Dendritic Cells - metabolism | Tumor Microenvironment - drug effects | Enzyme-Linked Immunosorbent Assay | Intercellular Adhesion Molecule-1 - immunology | Tissue Culture Techniques | Cells, Cultured | Vascular Endothelial Growth Factor A - immunology | Tumor Microenvironment - immunology | B7-2 Antigen - metabolism | Cell Differentiation - immunology | Chemokine CXCL1 - immunology | Intercellular Adhesion Molecule-1 - metabolism | Colorectal Neoplasms - immunology | Chemokine CCL2 - pharmacology | Cell Differentiation - drug effects | Chemokine CXCL5 - immunology | Interferon-gamma - immunology | Lipopolysaccharides - pharmacology | Aged | HLA-DR Antigens - immunology | Colorectal Neoplasms - pathology | Culture Media, Conditioned - metabolism | Care and treatment | Dendritic cells | Vascular endothelial growth factor | Colorectal cancer | Tumors | CD86 antigen | Colorectal carcinoma | Biochemistry | Metastasis | Kinases | Lipopolysaccharides | Proteins | Angiogenesis | Signal transduction | Lymphocytes | Inhibition | Pretreatment | Conditioning | Antigens | Immune response | Cytokines | Maturation | Secretion | Neutrophils | Interleukin 12 | CD80 antigen | Inflammation | CD83 antigen | Interleukin 10 | Ligands | Histocompatibility antigen HLA | Prostate cancer | Chemokines | Monocyte chemoattractant protein 1 | Cancer | Apoptosis | Index Medicus
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 02/2016, Volume 65, Issue 2, pp. 193 - 204
Immunosuppression in tumor microenvironments critically affects the success of cancer immunotherapy. Here, we focused on the role of interleukin (IL)-6/signal... 
HLA class II | Antigen presentation | Dendritic cells | IL-12 | Helper T cells | STAT3 | IMMUNOLOGY | MELANOMA | ONCOLOGY | IMMUNOTHERAPY | COLORECTAL-CANCER | IN-VIVO | ANTI-INTERLEUKIN-6 MONOCLONAL-ANTIBODY | SILTUXIMAB | SUPPRESSOR-CELLS | DIFFERENTIATION | EPITOPE LONG PEPTIDE | T-Lymphocyte Subsets - immunology | Colorectal Neoplasms - genetics | Dendritic Cells - immunology | Humans | Arginase - metabolism | CD11 Antigens - metabolism | HLA-DR Antigens - genetics | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | T-Cell Antigen Receptor Specificity - immunology | Dendritic Cells - drug effects | Histocompatibility Antigens Class II - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Cell Membrane - metabolism | Epitopes, T-Lymphocyte - immunology | HLA-DR Antigens - metabolism | Interleukin-6 - metabolism | Colorectal Neoplasms - metabolism | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Interleukin-12 - biosynthesis | Signal Transduction | Antigens, Neoplasm - immunology | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | Antigen Presentation - immunology | B7-2 Antigen - metabolism | Colorectal Neoplasms - immunology | Histocompatibility Antigens Class II - immunology | Interleukin-6 - pharmacology | T-Lymphocyte Subsets - metabolism | Cyclooxygenase 2 - metabolism | HLA-DR Antigens - immunology | Histocompatibility Antigens Class II - genetics | Interferon-gamma - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 46, pp. E9942 - E9951
Immunotherapies, particularly checkpoint inhibitors, have set off a revolution in cancer therapy by releasing the power of the immune system. However, only... 
Mesothelin | Mucin 16 | Immunotherapy | Immunopeptidome | Ovarian cancer | SURVIVAL | ovarian cancer | mucin 16 | MULTIDISCIPLINARY SCIENCES | IMMUNE PRIVILEGE | immunopeptidome | TUMOR | ANTIGENS | CANCER-IMMUNOTHERAPY | IDENTIFICATION | mesothelin | ADVANCED MELANOMA | immunotherapy | EXPRESSION | T-CELLS | Membrane Glycoproteins - analysis | Kallikreins - immunology | CA-125 Antigen - immunology | Galectin 1 - immunology | Membrane Glycoproteins - metabolism | Humans | Vaccination | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Neoplasms, Glandular and Epithelial - metabolism | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | Neoplasms, Glandular and Epithelial - immunology | Histocompatibility Antigens Class I - metabolism | Female | Histocompatibility Antigens Class II - metabolism | Ovarian Neoplasms - metabolism | Membrane Glycoproteins - immunology | HLA-DR Antigens - metabolism | Neoplasms, Glandular and Epithelial - pathology | GPI-Linked Proteins - immunology | Histocompatibility Antigens Class I - immunology | Membrane Proteins - immunology | Antigen Presentation - immunology | Membrane Glycoproteins - genetics | Histocompatibility Antigens Class II - immunology | Carcinoma, Ovarian Epithelial | Ligands | HLA-DR Antigens - immunology | Ovarian Neoplasms - immunology | Physiological aspects | Antigens | Peptides | Health aspects | Transcription factors | Ovarian carcinoma | Transcription | Gene expression | Immune systems | Molecules | Mucin | Immune checkpoint | Histocompatibility antigen HLA | Immune system | Cancer | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2009, Volume 206, Issue 1, pp. 169 - 181
The Journal of Experimental Medicine Adequate numbers and functional maturity are needed for leukocytes to exhibit a protective role in host defense. During... 
ADAPTIVE IMMUNITY | MEDICINE, RESEARCH & EXPERIMENTAL | EPIDERMAL LANGERHANS CELLS | IN-UTERO | HUMAN-FETUS | CYTOKINE RESPONSES | PERIPHERAL-BLOOD | BIRBECK GRANULES | IMMUNOLOGY | T-CELLS | DISTINCT POPULATIONS | BLOOD DENDRITIC CELLS | Mannose-Binding Lectins - metabolism | Skin - cytology | Cell Proliferation | Leukocyte Common Antigens - metabolism | Antigen-Presenting Cells - cytology | Dendritic Cells - immunology | Humans | Transforming Growth Factor beta1 - metabolism | Glycoproteins - metabolism | Ki-67 Antigen - metabolism | Antigens, CD - metabolism | Lymphocyte Culture Test, Mixed | Leukocytes - immunology | Lectins, C-Type - metabolism | Langerhans Cells - immunology | Dermis - cytology | HLA-DR Antigens - metabolism | Dendritic Cells - metabolism | Leukocytes - cytology | Skin - embryology | Skin - immunology | Cytokines - metabolism | Phagocytosis - immunology | Escherichia coli - immunology | Keratinocytes - cytology | Antigen-Presenting Cells - immunology | Embryo, Mammalian - embryology | Embryo, Mammalian - cytology | Embryo, Mammalian - immunology | Keratinocytes - metabolism | Antigens, CD1 - metabolism | T-Lymphocytes - immunology | Dendritic Cells - cytology | Langerhans Cells - metabolism | Leukocytes - metabolism | Langerhans Cells - cytology | Culture Media, Conditioned - metabolism | Epidermis - cytology | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2013, Volume 33, Issue 10, pp. 4216 - 4233
Neurogenesis must be properly regulated to ensure that cell production does not exceed the requirements of the growing cerebral cortex, yet our understanding... 
HUMAN NEOCORTEX | BRAIN TRAUMA | RADIAL GLIAL-CELLS | HYPOXIA-ISCHEMIA | ADULT HIPPOCAMPAL NEUROGENESIS | SPINAL-CORD | ACTIVATED MICROGLIA | DENTATE GYRUS | NEUROSCIENCES | INTERMEDIATE PROGENITOR CELLS | PREFRONTAL CORTEX | Age Factors | Embryo, Mammalian | Minocycline - pharmacology | Cell Count | Male | Cerebral Cortex - cytology | Lipopolysaccharide Receptors - metabolism | Indoles - metabolism | Microglia - physiology | Cerebral Ventricles - growth & development | Female | Macaca | Microfilament Proteins - metabolism | Cerebral Ventricles - embryology | HLA-DR Antigens - metabolism | Animals, Newborn | Calcium-Binding Proteins - metabolism | Lipopolysaccharides - toxicity | Neural Stem Cells - drug effects | Phagocytosis - physiology | Neural Stem Cells - physiology | Rats | Cerebral Cortex - transplantation | T-Box Domain Proteins - metabolism | Nerve Tissue Proteins - metabolism | Pregnancy | Microscopy, Confocal | Animals | Analysis of Variance | Cerebral Cortex - embryology | Neurogenesis - physiology | Cerebral Cortex - growth & development | Luminescent Proteins - genetics | Cerebral Ventricles - cytology | Proliferating Cell Nuclear Antigen - metabolism | Prenatal Exposure Delayed Effects - chemically induced | Prenatal Exposure Delayed Effects - pathology | Luminescent Proteins - metabolism | Nitric Oxide Synthase Type II - metabolism | Index Medicus
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2009, Volume 32, Issue 3, pp. 231 - 239
Journal Article