X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
hmg-1 (218) 218
animals (125) 125
humans (117) 117
index medicus (102) 102
male (97) 97
hmgb1 (88) 88
inflammation (87) 87
mice (85) 85
hmgb1 protein - metabolism (84) 84
mediator (61) 61
biochemistry & molecular biology (56) 56
female (53) 53
cells (49) 49
rats (47) 47
sepsis (46) 46
chromosomal proteins (45) 45
expression (41) 41
hmgb1 protein - genetics (41) 41
cytokine (38) 38
activation (37) 37
hmgb1 protein - blood (37) 37
middle aged (37) 37
hmgb1 protein (35) 35
cell biology (34) 34
release (33) 33
molecular sequence data (32) 32
dna (29) 29
protein binding (28) 28
chemical and pharmacologic phenomena (27) 27
cytokines (27) 27
proteins (27) 27
hmgb1 protein - immunology (26) 26
immunology (26) 26
adult (25) 25
enzyme-linked immunosorbent assay (25) 25
amino acid sequence (24) 24
medicine, research & experimental (24) 24
protein (24) 24
receptor (24) 24
aged (23) 23
cells, cultured (23) 23
binding (21) 21
cell line (21) 21
disease models, animal (21) 21
dna-binding (21) 21
macrophages (21) 21
time factors (20) 20
mice, inbred balb c (19) 19
amphoterin (18) 18
analysis (18) 18
hmgb1 protein - antagonists & inhibitors (18) 18
hmgb1 protein - chemistry (18) 18
neurite outgrowth (18) 18
transcriptional activation (18) 18
tumor-necrosis-factor (18) 18
chromatin protein (17) 17
hmgb1 protein - physiology (17) 17
injury (17) 17
research (17) 17
surgery (17) 17
base sequence (16) 16
dna - metabolism (16) 16
rheumatology (16) 16
blotting, western (15) 15
glycation end-products (15) 15
high mobility group box 1 (15) 15
high-mobility group box 1 (15) 15
macrophages - metabolism (15) 15
mobility group box-1 (15) 15
monocytes (15) 15
physiological aspects (15) 15
research article (15) 15
rna, messenger - metabolism (15) 15
apoptosis (14) 14
biophysics (14) 14
chromatin (14) 14
gastroenterology & hepatology (14) 14
high mobility group proteins - metabolism (14) 14
immunohistochemistry (14) 14
oncology (14) 14
pathogenesis (14) 14
rats, wistar (14) 14
receptor for advanced glycation end products (14) 14
transcription (14) 14
antibodies (13) 13
arthritis (13) 13
biomarkers - blood (13) 13
critical care medicine (13) 13
gene expression regulation (13) 13
hmgb1 protein - pharmacology (13) 13
lipopolysaccharide (13) 13
protein hmgb1 (13) 13
rage (13) 13
acute lung injury (12) 12
chromatin protein hmgb1 (12) 12
endotoxin (12) 12
hematology (12) 12
high mobility group proteins - genetics (12) 12
rats, sprague-dawley (12) 12
disease (11) 11
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2019, Volume 511, Issue 3, pp. 665 - 670
The interaction of high mobility group box 1 (HMGB1), which is secreted from immune and dying cells during cellular infection and injury, and receptor for... 
Sepsis | Inflammation | HMGB1 | RAGE | Papaverine | Macrophage | SITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | 1 PROTEIN | ENDPRODUCTS RAGE | AMPHOTERIN | BIOPHYSICS | BLOCKADE | HMG-1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 26, pp. 11942 - 11947
During infection, vertebrates develop "sickness syndrome," characterized by fever, anorexia, behavioral withdrawal, acute-phase protein responses, and... 
Anger | Cytokines | Cell lines | Toll like receptors | Antibodies | Fibroblasts | Sepsis | Inflammation | Macrophages | CHO cells | Infection | Innate immunity | Proximity ligation assay | Sterile inflammation | TNF | sterile inflammation | infection | PROTEIN | innate immunity | MULTIDISCIPLINARY SCIENCES | HIGH-MOBILITY-GROUP-BOX-1 | MOBILITY GROUP BOX-1 | proximity ligation assay | SEPSIS | HMG-1 | Cricetulus | Lymphocyte Antigen 96 - metabolism | Humans | Molecular Sequence Data | DNA Primers - genetics | HMGB1 Protein - immunology | HMGB1 Protein - genetics | Toll-Like Receptor 4 - deficiency | HMGB1 Protein - chemistry | Base Sequence | HMGB1 Protein - metabolism | Binding Sites | Macrophages - immunology | CHO Cells | Recombinant Proteins - metabolism | Amino Acid Sequence | Cricetinae | Mutagenesis, Site-Directed | Signal Transduction | Rats | Recombinant Proteins - chemistry | Toll-Like Receptor 4 - genetics | Recombinant Proteins - genetics | Cysteine - chemistry | Immunity, Innate | Toll-Like Receptor 4 - metabolism | Macrophage Activation | Mice, Knockout | Macrophages - metabolism | Animals | Recombinant Proteins - immunology | Protein Binding | Mice | In Vitro Techniques | Cytokines - biosynthesis | Amino Acid Substitution | Cysteine | Immune response | Tumor necrosis factor | Research | Properties | Observations | Protein binding | Biological Sciences
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 06/2008, Volume 117, Issue 25, pp. 3216 - 3226
Journal Article
Journal Article
Journal Article
Journal Article
FRESENIUS ENVIRONMENTAL BULLETIN, ISSN 1018-4619, 2019, Volume 28, Issue 10, pp. 7069 - 7075
Severe acute pancreatitis (SAP) is a common acute inflammation in pancreas with a high mortality rate. Recently HMGB1 is reported to be involved in the... 
CELLS | ENVIRONMENTAL SCIENCES | Severe acute pancreatitis (SAP) | liver injury | ACTIVATION | MEDIATOR | HMGB1 A-BOX treatment | DEATH | inflammation cytokine | RELEASE | HMG-1
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2006, Volume 26, Issue 24, pp. 6413 - 6421
Cerebral ischemic injury proceeds with excitotoxicity-induced acute neuronal death in the ischemic core and with delayed damage processes in the penumbra.... 
MCAO | Inflammation | HMGB1 | Ischemia | shRNA | PAMAM-Arg | ACTIVATION | NEUROSCIENCES | ischemia | CELL-DEATH | NEURITE OUTGROWTH | inflammation | CHROMATIN PROTEIN HMGB1 | CEREBRAL-ARTERY OCCLUSION | MOBILITY GROUP BOX-1 | HMG-1 | GLYCATION END-PRODUCTS | Inflammation - pathology | Microglia - metabolism | Gene Expression - drug effects | Embryo, Mammalian | Culture Media, Conditioned - pharmacology | Male | Repressor Proteins - pharmacology | Infarction, Middle Cerebral Artery - metabolism | RNA, Messenger - metabolism | Brain - metabolism | Inflammation - metabolism | Staurosporine - toxicity | Microglia - physiology | Transfection - methods | Time Factors | Infarction, Middle Cerebral Artery - complications | Enzyme Inhibitors - toxicity | Gene Expression - physiology | Reverse Transcriptase Polymerase Chain Reaction - methods | Neurons - metabolism | Neurons - drug effects | Repressor Proteins - metabolism | Blotting, Western - methods | High Mobility Group Proteins - metabolism | HMGB1 Protein | Cells, Cultured | Rats | Infarction, Middle Cerebral Artery - pathology | Inflammation - etiology | Rats, Sprague-Dawley | Animals | Excitatory Amino Acid Agonists - toxicity | Cell Death - physiology | High Mobility Group Proteins - pharmacology | Brain - pathology | Blotting, Northern - methods | Mice | N-Methylaspartate - toxicity
Journal Article
Artificial Cells, Nanomedicine, and Biotechnology, ISSN 2169-1401, 12/2019, Volume 47, Issue 1, pp. 1067 - 1074
Elevated free fatty acids (FFAs) are a risk factor for type 2 diabetes. Endothelial dysfunction induced by high levels of FFAs is one of the mechanisms related... 
AMPK | free fatty acids (FFAs) | Vildagliptin | NLRP3 inflammasome | HMG-1 | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | INJURY | HMGB1 | METABOLISM | vildagliptin | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GLUCOSE | DISEASE
Journal Article
Journal of Ocular Pharmacology and Therapeutics, ISSN 1080-7683, 12/2018, Volume 34, Issue 10, pp. 659 - 669
High mobility group box 1 (HMGB1) contributes to adverse disease outcome in Pseudomonas aeruginosa keratitis. This study tests Box A, an HMGB1 antagonist, in a... 
Box A | RAGE | cornea | mice | TLR4 | TARGET | PROTEIN | ENDOTOXIN | INJURY | RECEPTOR | IL-6 | A-BOX | LATE MEDIATOR | OPHTHALMOLOGY | PHARMACOLOGY & PHARMACY | HMG-1 | EXPRESSION
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e89450
Aim: Glycyrrhizin (GL) has been reported to protect against ischemia and reperfusion (I/R)-induced injury by inhibiting the cytokine activity of high mobility... 
ISCHEMIA-REPERFUSION INJURY | STROKE | CELLS | LIVER-INJURY | CHROMATIN PROTEIN HMGB1 | POSTISCHEMIC BRAIN | MEDIATOR | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MOBILITY GROUP BOX-1 | HMG-1 | Neuroprotective Agents - therapeutic use | Cerebral Infarction - drug therapy | Inflammation - pathology | Apoptosis - drug effects | Reperfusion Injury - drug therapy | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Cerebral Infarction - complications | Reperfusion Injury - blood | Inflammation - complications | Brain Ischemia - blood | Glycyrrhizic Acid - pharmacology | Neuroprotective Agents - pharmacology | Infarction, Middle Cerebral Artery - complications | Inflammation - drug therapy | Cerebral Infarction - blood | HMGB1 Protein - metabolism | Infarction, Middle Cerebral Artery - drug therapy | Reperfusion Injury - complications | p38 Mitogen-Activated Protein Kinases - metabolism | HMGB1 Protein - antagonists & inhibitors | Cerebral Infarction - pathology | Brain Ischemia - complications | Reperfusion Injury - pathology | Antioxidants - pharmacology | Infarction, Middle Cerebral Artery - pathology | Rats, Sprague-Dawley | Infarction, Middle Cerebral Artery - blood | Glycyrrhizic Acid - therapeutic use | Animals | MAP Kinase Signaling System - drug effects | Brain Ischemia - drug therapy | Brain Ischemia - pathology | Oxidative Stress - drug effects | Oxidative stress | Brain | Chromosomal proteins | Cytokines | Ischemia | Inflammation | Enzyme-linked immunosorbent assay | Apoptosis | Occlusion | Cytochrome | Cerebral cortex | Kinases | Caspase-3 | HMGB1 protein | Western blotting | Interleukin 6 | Reperfusion | Cerebral blood flow | Rodents | Inhibition | Pretreatment | Glycyrrhizin | Cortex | Rats | Caspase | JNK protein | Tumor necrosis factor-α | Nitric-oxide synthase | Neurological diseases | Polymerase chain reaction | Cytochrome c | Serum levels | Signaling | Injury prevention | Molecular modelling | Nitric oxide | Immunofluorescence
Journal Article