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by Beaumont, Robin N and Warrington, Nicole M and Cavadino, Alana and Tyrrell, Jessica and Nodzenski, Michael and Horikoshi, Momoko and Geller, Frank and Myhre, Ronny and Richmond, Rebecca C and Paternoster, Lavinia and Bradfield, Jonathan P and Kreiner-Møller, Eskil and Huikari, Ville and Metrustry, Sarah and Lunetta, Kathryn L and Painter, Jodie N and Hottenga, Jouke-Jan and Allard, Catherine and Barton, Sheila J and Espinosa, Ana and Marsh, Julie A and Potter, Catherine and Zhang, Ge and Ang, Wei and Berry, Diane J and Bouchard, Luigi and Das, Shikta and Hakonarson, Hakon and Heikkinen, Jani and Helgeland, Øyvind and Hocher, Berthold and Hofman, Albert and Inskip, Hazel M and Jones, Samuel E and Kogevinas, Manolis and Lind, Penelope A and Marullo, Letizia and Medland, Sarah E and Murray, Anna and Murray, Jeffrey C and Njølstad, Pål R and Nohr, Ellen A and Reichetzeder, Christoph and Ring, Susan M and Ruth, Katherine S and Santa-Marina, Loreto and Scholtens, Denise M and Sebert, Sylvain and Sengpiel, Verena and Tuke, Marcus A and Vaudel, Marc and Weedon, Michael N and Willemsen, Gonneke and Wood, Andrew R and Yaghootkar, Hanieh and Muglia, Louis J and Bartels, Meike and Relton, Caroline L and Pennell, Craig E and Chatzi, Leda and Estivill, Xavier and Holloway, John W and Boomsma, Dorret I and Montgomery, Grant W and Murabito, Joanne M and Spector, Tim D and Power, Christine and Järvelin, Marjo-Ritta and Bisgaard, Hans and Grant, Struan F A and Sørensen, Thorkild I A and Jaddoe, Vincent W and Jacobsson, Bo and Melbye, Mads and McCarthy, Mark I and Hattersley, Andrew T and Hayes, M Geoffrey and Frayling, Timothy M and Hivert, Marie-France and Felix, Janine F and Hyppönen, Elina and Lowe, William L and Evans, David M and Lawlor, Debbie A and Feenstra, Bjarke and Freathy, Rachel M and Early Growth Genetics (EGG) Consortium and Early Growth Genetics EGG and Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Department of Obstetrics and Gynecology and Sahlgrenska Academy
Human molecular genetics, ISSN 1460-2083, 02/2018, Volume 27, Issue 4, pp. 742 - 756
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 05/2013, Volume 110, Issue 24, pp. 9920 - 9925
The ten-eleven translocation (TET) family of methylcytosine dioxygenases initiates demethylation of DNA and is associated with tumorigenesis in many cancers;... 
Genes | DNA | Cell lines | Breast cancer | Breast neoplasms | Gene expression regulation | Promoter regions | Metastasis | Embryonic stem cells | Tumors | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Wnt1 Protein - genetics | Prognosis | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - metabolism | Humans | Immunoblotting | Male | Transplantation, Heterologous | Gene Expression Profiling | Wnt1 Protein - metabolism | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Neoplasm Metastasis | HMGA2 Protein - metabolism | RNA Interference | HMGA2 Protein - genetics | Mammary Neoplasms, Experimental - pathology | Female | Proto-Oncogene Proteins - metabolism | Mice, Inbred C57BL | Kaplan-Meier Estimate | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | Genetic aspects | Research | Translocation (Genetics) | Genetic regulation | Index Medicus | Biological Sciences
Journal Article
Cell (Cambridge), ISSN 0092-8674, 08/2006, Volume 126, Issue 3, pp. 503 - 514
Journal Article
Modern pathology, ISSN 0893-3952, 2018, Volume 32, Issue 5, pp. 627 - 638
Although non-small-cell lung cancer is a leading cause of cancer-related deaths, the molecular characterization and classification of its genetic alterations has drastically changed treatment options... 
Life Sciences & Biomedicine | Pathology | Science & Technology | Genomic Instability | Lung Neoplasms - drug therapy | Proto-Oncogene Proteins c-mdm2 - genetics | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Cyclin-Dependent Kinase 4 - genetics | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | HMGA2 Protein - genetics | Female | Retrospective Studies | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Mutation Rate | Proto-Oncogene Proteins c-met - genetics | Phenotype | Gene Amplification | GTP Phosphohydrolases - genetics | Protein Kinase Inhibitors - therapeutic use | Aged | Biomarkers, Tumor - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Tyrosine | Immunohistochemistry | MDM2 protein | p53 Protein | Lung cancer | Lung carcinoma | Hybridization | Kinases | Cyclin-dependent kinase 4 | Genomic instability | c-Met protein | Gene frequency | Medical prognosis | Fluorescence in situ hybridization | Protein-tyrosine kinase | Tumors | Index Medicus | Non-small-cell lung cancer | Translational research | Genetics research
Journal Article
Nature (London), ISSN 1476-4687, 12/2013, Volume 505, Issue 7482, pp. 212 - 217
...) for the let-7 microRNA (miRNA) family. Hmga2 can promote the transformation of lung cancer cells independent of protein-coding function but dependent upon the presence of let-7 sites... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Receptors, Transforming Growth Factor beta - genetics | Cell Proliferation | Humans | Lung Neoplasms - pathology | MicroRNAs - metabolism | Proteoglycans - deficiency | RNA Isoforms - metabolism | HMGA2 Protein - genetics | Gene Expression Regulation, Neoplastic - genetics | Disease Models, Animal | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Argonaute Proteins - metabolism | RNA Isoforms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Proteoglycans - biosynthesis | Disease Progression | Neoplasm Metastasis - genetics | Receptors, Transforming Growth Factor beta - biosynthesis | Animals | Cell Line, Tumor | Binding, Competitive - genetics | Mice | MicroRNAs - genetics | Transcription, Genetic - genetics | Neoplasm Invasiveness - genetics | Transforming Growth Factor beta - metabolism | Proteoglycans - genetics | Receptors, Transforming Growth Factor beta - deficiency | RNA sequencing | Gene targeting | Development and progression | Genetic aspects | Genetic transcription | Lung cancer, Non-small cell | Identification and classification | Methods | Proteins | Hypothesis testing | Survival analysis | Hypotheses | Transplants & implants | Lung cancer | Genomes | Tumorigenesis | Mutation | Gene expression | Tumors | Index Medicus
Journal Article
by Ng, Maggie C. Y and Shriner, Daniel and Chen, Brian H and Li, Jiang and Chen, Wei-Min and Guo, Xiuqing and Liu, Jiankang and Bielinski, Suzette J and Yanek, Lisa R and Nalls, Michael A and Comeau, Mary E and Rasmussen-Torvik, Laura J and Jensen, Richard A and Evans, Daniel S and Sun, Yan V and An, Ping and Patel, Sanjay R and Lu, Yingchang and Long, Jirong and Armstrong, Loren L and Wagenknecht, Lynne and Yang, Lingyao and Snively, Beverly M and Palmer, Nicholette D and Mudgal, Poorva and Langefeld, Carl D and Keene, Keith L and Freedman, Barry I and Mychaleckyj, Josyf C and Nayak, Uma and Raffel, Leslie J and Goodarzi, Mark O and Chen, Y-D Ida and Taylor, Herman A and Correa, Adolfo and Sims, Mario and Couper, David J and Pankow, James S and Boerwinkle, Eric and Adeyemo, Adebowale and Doumatey, Ayo and Chen, Guanjie and Mathias, Rasika A and Vaidya, Dhananjay and Singleton, Andrew B and Zonderman, Alan B and Igo, Robert P and Sedor, John R and Zondervan, Krina T and Kabagambe, Edmond K and Siscovick, David S and McKnight, Barbara and Rice, Kenneth and Liu, Yongmei and Hsueh, Wen-Chi and Zhao, Wei and Bielak, Lawrence F and Kraja, Aldi and Province, Michael A and Bottinger, Erwin P and Gottesman, Omri and Cai, Qiuyin and Zheng, Wei and Blot, William J and Lowe, William L and Pacheco, Jennifer A and Crawford, Dana C and Yang, Tsun-Po and Wilk, Alicja and Grundberg, Elin and Tsoka, Sophia and Rich, Stephen S and Hayes, M. Geoffrey and Shu, Xiao-Ou and Loos, Ruth J. F and Borecki, Ingrid B and Peyser, Patricia A and Cummings, Steven R and Psaty, Bruce M and Fornage, Myriam and Iyengar, Sudha K and Evans, Michele K and Becker, Diane M and Kao, W. H. Linda and Wilson, James G and Rotter, Jerome I and Sale, Michèle M and Liu, Simin and Rotimi, Charles N and Bowden, Donald W and Elston, R.C and Goddard, K and Olson, J and Ialacci, S and Edwards, S and Fondran, C and Horvath, A and Jun, G and Kramp, K and Slaughter, M and ... and FIND Consortium and DIAGRAM Consortium and MEta-Anal Type 2 Diabet and eMERGE Consortium and MuTHER Consortium and MEta-analysis of type 2 DIabetes in African Americans Consortium and the MuTHER Consortium and for the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium and the DIAGRAM Consortium and the FIND Consortium and the eMERGE Consortium
PLoS genetics, ISSN 1553-7390, 08/2014, Volume 10, Issue 8, pp. e1004517 - e1004517
Journal Article