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Nature (London), ISSN 1476-4687, 11/2009, Volume 462, Issue 7269, pp. 99 - 103
Journal Article
Journal of leukocyte biology, ISSN 0741-5400, 09/2009, Volume 86, Issue 3, pp. 655 - 662
.... The nuclear protein HMGB1 has previously been demonstrated to act as an alarmin and to promote inflammation upon extracellular release, yet its mode of action is still not well defined... 
innate cell‐mediated immunity | cell activation | Innate cell-mediated immunity | Cell activation | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | Coculture Techniques | Cytokines - analysis | Humans | Synovial Membrane - immunology | HMGB1 Protein - immunology | HMGB1 Protein - isolation & purification | Lipopolysaccharides - immunology | HMGB1 Protein - genetics | Recombinant Proteins - isolation & purification | Toll-Like Receptor 9 - immunology | Signal Transduction - immunology | HMGB1 Protein - pharmacology | Leukocytes, Mononuclear - immunology | Fibroblasts - metabolism | Inflammation Mediators - immunology | Cell Survival - drug effects | Biotinylation | Leukocytes, Mononuclear - drug effects | Oligodeoxyribonucleotides - immunology | Cells, Cultured | Interleukin-1beta - immunology | Rats | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Recombinant Proteins - pharmacology | Synovial Membrane - metabolism | Arthritis, Rheumatoid - pathology | Animals | Recombinant Proteins - immunology | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Interleukin-6 - biosynthesis | Toll-Like Receptor 2 - immunology | Fibroblasts - immunology | Ligands | Toll-Like Receptor 1 - immunology | Index Medicus
Journal Article
Journal Article
PLoS pathogens, ISSN 1553-7366, 2010, Volume 6, Issue 4, pp. 1 - 15
... pattern recognition receptors such as Toll-like receptors (TLRs), and they undergo a maturation process characterized by increased expression of HLA class I proteins... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Oligonucleotide Array Sequence Analysis | Coculture Techniques | Dendritic Cells - immunology | Humans | HMGB1 Protein - immunology | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand - immunology | HIV Infections - immunology | Signal Transduction - immunology | Flow Cytometry | HMGB1 Protein - metabolism | Killer Cells, Natural - immunology | Dendritic Cells - virology | Dendritic Cells - metabolism | Inhibitor of Apoptosis Proteins - biosynthesis | Receptor Cross-Talk | Cell Separation | Killer Cells, Natural - virology | HIV Infections - virology | Cell Communication | TNF-Related Apoptosis-Inducing Ligand - immunology | TNF-Related Apoptosis-Inducing Ligand - metabolism | CASP8 and FADD-Like Apoptosis Regulating Protein - biosynthesis | Microscopy, Confocal | HIV-1 - immunology | Apoptosis - immunology | Inhibitor of Apoptosis Proteins - immunology | CASP8 and FADD-Like Apoptosis Regulating Protein - immunology | Killer Cells, Natural - metabolism | Cytotoxicity, Immunologic - immunology | HIV Infections - metabolism | Killer cells | Chromosomal proteins | Dendritic cells | Physiological aspects | HIV patients | Research | Health aspects | Index Medicus | HIV Infections | HIV-1 | Killer Cells, Natural | Dendritic Cells | Inhibitor of Apoptosis Proteins | Signal Transduction | HMGB1 Protein | Receptors, TNF-Related Apoptosis-Inducing Ligand | Life Sciences | TNF-Related Apoptosis-Inducing Ligand | Immunology | CASP8 and FADD-Like Apoptosis Regulating Protein | Apoptosis | Cytotoxicity, Immunologic | Proteins | Infections | Cells | Immune system
Journal Article
Nature communications, ISSN 2041-1723, 10/2016, Volume 7, Issue 1, pp. 13280 - 13280
Sepsis, severe sepsis and septic shock are the main cause of mortality in non-cardiac intensive care units. Immunometabolism has been linked to sepsis;... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Interleukin-18 - immunology | Phosphorylation | eIF-2 Kinase - metabolism | Humans | Male | HMGB1 Protein - immunology | HMGB1 Protein - secretion | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Macrophages - secretion | Female | Membrane Proteins - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Disease Models, Animal | eIF-2 Kinase - genetics | Interleukin-1beta - secretion | Sepsis - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Coinfection - immunology | Carrier Proteins - antagonists & inhibitors | Interleukin-1beta - immunology | Membrane Proteins - immunology | Naphthoquinones - pharmacology | Thyroid Hormones - genetics | eIF-2 Kinase - antagonists & inhibitors | Mice, Knockout | Thyroid Hormones - immunology | Carrier Proteins - genetics | Coinfection - microbiology | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Membrane Proteins - antagonists & inhibitors | Thyroid Hormones - metabolism | Inflammasomes - immunology | Myeloid Cells - metabolism | Interleukin-18 - secretion | Mice | Mice, Inbred BALB C | Glycolysis - immunology | Sepsis - microbiology | Index Medicus
Journal Article
Arthritis research & therapy, ISSN 1478-6354, 08/2011, Volume 13, Issue 4, pp. R136 - R136
Introduction: In addition to its direct proinflammatory activity, extracellular high mobility group box protein 1 (HMGB1... 
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Immunohistochemistry | Interleukin-1beta - pharmacology | Interleukin-1alpha - immunology | Humans | Lipopolysaccharides - metabolism | Synovial Membrane - immunology | Interleukin-1alpha - metabolism | HMGB1 Protein - immunology | Synovial Membrane - drug effects | Lipopolysaccharides - immunology | Arthritis, Rheumatoid - metabolism | Inflammation - metabolism | HMGB1 Protein - pharmacology | Interleukin-1beta - metabolism | HMGB1 Protein - metabolism | Inflammation Mediators - metabolism | Tumor Necrosis Factor-alpha - immunology | Osteoarthritis - pathology | Cytokines - immunology | Fibroblasts - metabolism | Inflammation Mediators - immunology | Enzyme-Linked Immunosorbent Assay | Osteoarthritis - immunology | Cells, Cultured | Interleukin-1beta - immunology | Osteoarthritis - metabolism | Inflammation - immunology | Synovial Membrane - metabolism | Arthritis, Rheumatoid - pathology | Phenotype | Fibroblasts - drug effects | Lipopolysaccharides - pharmacology | Fibroblasts - immunology | Arthritis, Rheumatoid - immunology | Interleukin-1alpha - pharmacology | Tumor Necrosis Factor-alpha - biosynthesis | Cytokines - biosynthesis | Complications and side effects | Care and treatment | Rheumatoid arthritis | Fibroblasts | Physiological aspects | Research | Diagnosis | Index Medicus
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 08/2014, Volume 134, Issue 2, pp. 440 - 450.e3
Background The receptor for advanced glycation end products (RAGE) shares common ligands and signaling pathways with TLR4, a key mediator of house dust mite (... 
Allergy and Immunology | TSLP | allergic sensitization | epithelium | IL-25 | RAGE | HMGB1 | TLR4 | IL-1α | IL-33 | Asthma | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Inflammation - pathology | Interleukin-1alpha - immunology | Dermatophagoides pteronyssinus - immunology | Dendritic Cells - immunology | Dendritic Cells - pathology | Male | HMGB1 Protein - immunology | Adoptive Transfer | Respiratory Hypersensitivity - pathology | HMGB1 Protein - genetics | Allergens - administration & dosage | Interleukins - genetics | Allergens - immunology | Toll-Like Receptor 4 - deficiency | Interleukins - immunology | Interleukin-1alpha - genetics | Receptors, Immunologic - immunology | HMGB1 Protein - antagonists & inhibitors | Receptor for Advanced Glycation End Products | Lung - pathology | Signal Transduction | Interleukin-33 | Gene Expression Regulation | Receptors, Immunologic - deficiency | Toll-Like Receptor 4 - genetics | Antibodies, Neutralizing - pharmacology | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Respiratory Hypersensitivity - immunology | Administration, Intranasal | Mice, Knockout | Respiratory Hypersensitivity - genetics | Animals | Lung - drug effects | Blattellidae - immunology | Inflammation - genetics | Mice | Receptors, Immunologic - genetics | Dendritic Cells - transplantation | Lung - immunology | Drugstores | Neurosciences | Pharmacy | Studies | Statistical analysis | Ligands | Allergies | Chemokines | Methods | Immune system | Index Medicus | Abridged Index Medicus
Journal Article