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Nature (London), ISSN 1476-4687, 07/2012, Volume 488, Issue 7413, pp. 670 - 674
...)-1 beta, IL-18 and high-mobility group box 1 (HMGB1)(1-5). By studying HMGB1 release mechanisms, here we identify a role for double-stranded RNA-dependent protein kinase... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Crystallins - metabolism | Interleukin-6 - analysis | Phosphorylation | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | eIF-2 Kinase - metabolism | Humans | Salmonella Infections - immunology | Male | Salmonella Infections - metabolism | HMGB1 Protein - secretion | Interleukin-1beta - blood | eIF-2 Kinase - deficiency | Adenosine Triphosphate - pharmacology | CARD Signaling Adaptor Proteins - metabolism | Transfection | Interleukin-6 - blood | Rotenone - pharmacology | Female | Membrane Proteins - metabolism | Escherichia coli - physiology | Macrophages, Peritoneal - drug effects | eIF-2 Kinase - genetics | Calcium-Binding Proteins - metabolism | Cell Line | Salmonella typhimurium - physiology | Interleukin-18 - blood | Salmonella typhimurium - immunology | Inflammasomes - agonists | Mice, Inbred C57BL | Peritonitis - metabolism | Cells, Cultured | Escherichia coli - immunology | Antigens, Bacterial - pharmacology | Escherichia coli Infections - metabolism | eIF-2 Kinase - antagonists & inhibitors | Apoptosis Regulatory Proteins - metabolism | Animals | Carrier Proteins - metabolism | Bacterial Toxins - pharmacology | Uric Acid - pharmacology | RNA, Double-Stranded - immunology | RNA, Double-Stranded - pharmacology | Escherichia coli Infections - immunology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Macrophages, Peritoneal - metabolism | HMGB1 Protein - blood | Physiological aspects | Chromosomal proteins | Research | Cytokines | Aluminum | Health aspects | Proteins | E coli | Pathogenesis | Plasmids | Bone marrow | Bacteria | Kinases | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 07/2010, Volume 107, Issue 28, pp. 12611 - 12616
.... Asbestos-exposed HM activate poly(ADP-ribose) polymerase, secrete H₂O₂, deplete ATP, and translocate high-mobility group box 1 protein (HMGB1... 
Actinomycin | Asbestos | Cell death | Secretion | Plasma cells | Inflammation | Macrophages | Carcinogenesis | Necrosis | Apoptosis | Mesothelioma | Biomarker | Tumor necrosis factor-alpha | Chemoprevention | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Asbestos - metabolism | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Humans | Reactive Oxygen Species - pharmacology | Adenosine Diphosphate Ribose - metabolism | Adenosine Diphosphate Ribose - pharmacology | Carcinogens - metabolism | Asbestos - pharmacology | Pleural Neoplasms - metabolism | Inflammation - metabolism | Carcinogens - pharmacology | Cell Nucleus - metabolism | HMGB Proteins - pharmacology | HMGB1 Protein - pharmacology | HMGB1 Protein - metabolism | Cell Death | Mesocricetus | Female | HMGB Proteins - metabolism | Poly Adenosine Diphosphate Ribose - pharmacology | Epithelium - drug effects | Cricetinae | Cytokines - metabolism | Epithelium - metabolism | Hydrogen Peroxide - pharmacology | Necrosis - metabolism | Hydrogen Peroxide - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Macrophages - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Mesothelioma - metabolism | Poly(ADP-ribose) Polymerases - pharmacology | Cells - metabolism | Mice | Mice, Inbred BALB C | Cytokines - pharmacology | Prevention | Mesothelium | Chromosomal proteins | Research | Chemical properties | Health aspects | Index Medicus | Reactive oxygen species | Transformation | Deposits | Hydrogen peroxide | Cytokines | Cytotoxicity | HMGB1 protein | Nuclei | Carcinogens | Tumor necrosis factor-a | mesothelioma | ATP | Cytoplasm | tumor necrosis factor-alpha | Biological Sciences | chemoprevention | carcinogenesis | biomarker
Journal Article
Nature (London), ISSN 1476-4687, 11/2009, Volume 462, Issue 7269, pp. 99 - 103
Journal Article
Journal Article
Cell death and differentiation, ISSN 1476-5403, 07/2013, Volume 21, Issue 1, pp. 79 - 91
The immunogenic demise of cancer cells can be induced by various chemotherapeutics, such as anthracyclines and oxaliplatin, and provokes an immune response... 
quinacrine | apoptosis | U2OS cells | caspases | endoplasmic reticulum stress | Beclin 1 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Connexins - antagonists & inhibitors | RNA-Binding Proteins - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Cell Death - immunology | rho-Associated Kinases - antagonists & inhibitors | Antineoplastic Agents - toxicity | DNA-Binding Proteins - metabolism | Lysosomes - metabolism | Lysosomal-Associated Membrane Protein 1 - genetics | Myosin Type II - metabolism | RNA Interference | rho-Associated Kinases - metabolism | Adenosine Triphosphate - metabolism | HMGB1 Protein - metabolism | Cell Membrane - metabolism | Cell Death - drug effects | RNA-Binding Proteins - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | Connexins - genetics | rho-Associated Kinases - genetics | Lysosomal-Associated Membrane Protein 1 - antagonists & inhibitors | Microtubule-Associated Proteins - antagonists & inhibitors | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Connexins - metabolism | Nerve Tissue Proteins - metabolism | Animals | Autophagy-Related Protein 5 | Cell Line, Tumor | Lysosomal-Associated Membrane Protein 1 - metabolism | Mice | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Original Paper
Journal Article
Cardiovascular research, ISSN 1755-3245, 05/2017, Volume 113, Issue 6, pp. 586 - 597
Extracellular matrix (ECM) proteins accumulation contributes to the progression of pulmonary arterial hypertension (PAH... 
Pulmonary arterial hypertension | Receptor for advanced glycation end products | Pulmonary arterial smooth muscle cell | Extracellular matrix proteins | Pulmonary artery | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Phosphorylation | Vascular Remodeling | Humans | Middle Aged | Pyrroles | Male | Intracellular Signaling Peptides and Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | LIM Domain Proteins - metabolism | Hypertension, Pulmonary - chemically induced | Case-Control Studies | HMGB1 Protein - genetics | Cell Hypoxia | DNA-Binding Proteins - metabolism | Pulmonary Artery - metabolism | Transfection | RNA Interference | HMGB1 Protein - metabolism | Cytoskeletal Proteins - metabolism | Female | S100 Calcium Binding Protein beta Subunit - genetics | S100 Calcium Binding Protein beta Subunit - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Indoles | Receptor for Advanced Glycation End Products - genetics | Extracellular Matrix Proteins - metabolism | Disease Models, Animal | Receptor for Advanced Glycation End Products - metabolism | Cells, Cultured | Hypertension, Pulmonary - genetics | Hypertension, Pulmonary - metabolism | Animals | Ligands | Hypertension, Pulmonary - pathology | Pulmonary Artery - pathology | Index Medicus
Journal Article
Cell death and differentiation, ISSN 1476-5403, 10/2009, Volume 17, Issue 4, pp. 666 - 676
Journal Article