X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3754) 3754
Publication (578) 578
Book Chapter (17) 17
Book Review (14) 14
Conference Proceeding (11) 11
Dissertation (7) 7
Data Set (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (2621) 2621
animals (2481) 2481
hmgb1 protein - metabolism (2240) 2240
humans (2054) 2054
hmgb1 (1477) 1477
male (1417) 1417
mice (1376) 1376
inflammation (1285) 1285
chromosomal proteins (838) 838
hmgb1 protein - genetics (784) 784
female (770) 770
rats (724) 724
cell biology (655) 655
immunology (652) 652
activation (634) 634
hmgb1 protein (609) 609
apoptosis (586) 586
biochemistry & molecular biology (583) 583
expression (569) 569
chemical and pharmacologic phenomena (517) 517
proteins (514) 514
mice, inbred c57bl (494) 494
mobility group box-1 (491) 491
disease models, animal (477) 477
cells, cultured (466) 466
signal transduction (439) 439
cytokines (423) 423
protein (382) 382
cell line (380) 380
cells (378) 378
glycation end-products (377) 377
middle aged (368) 368
analysis (356) 356
receptor (352) 352
rats, sprague-dawley (351) 351
sepsis (342) 342
research (340) 340
rodents (321) 321
gene expression (320) 320
article (319) 319
toll-like receptor 4 - metabolism (307) 307
cell line, tumor (305) 305
medicine, research & experimental (304) 304
cancer (301) 301
adult (295) 295
nf-kappa b - metabolism (295) 295
rage (295) 295
hmgb1 protein - blood (294) 294
release (294) 294
receptor for advanced glycation end products (287) 287
research article (285) 285
hmgb1 protein - antagonists & inhibitors (278) 278
macrophages (273) 273
oncology (271) 271
toll-like receptors (269) 269
blotting, western (264) 264
health aspects (264) 264
enzyme-linked immunosorbent assay (261) 261
cytokines - metabolism (259) 259
inflammation - metabolism (253) 253
aged (252) 252
immunohistochemistry (245) 245
tumor necrosis factor-alpha - metabolism (243) 243
oxidative stress (238) 238
pharmacology & pharmacy (238) 238
protein binding (238) 238
signal transduction - drug effects (237) 237
nf-kappa-b (235) 235
hmgb1 protein - immunology (234) 234
medicine (233) 233
surgery (233) 233
hmgb1 protein - physiology (227) 227
multidisciplinary sciences (225) 225
mice, inbred balb c (224) 224
mice, knockout (222) 222
cytokine (220) 220
macrophages - metabolism (218) 218
physiological aspects (217) 217
autophagy (216) 216
chromatin protein hmgb1 (214) 214
hmgb1 protein - pharmacology (207) 207
neurosciences (204) 204
dendritic cells (201) 201
time factors (199) 199
ischemia (198) 198
receptors, immunologic - metabolism (198) 198
pathogenesis (196) 196
hmgb1 protein - biosynthesis (187) 187
pathology (186) 186
apoptosis - drug effects (185) 185
injury (183) 183
phosphorylation (182) 182
group box 1 (181) 181
dna (180) 180
up-regulation (180) 180
in-vitro (179) 179
rna, messenger - metabolism (177) 177
rats, wistar (174) 174
cell death (173) 173
necrosis (170) 170
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3592) 3592
Chinese (145) 145
Japanese (8) 8
Russian (7) 7
French (2) 2
German (2) 2
Czech (1) 1
Italian (1) 1
Korean (1) 1
Polish (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Death and Differentiation, ISSN 1350-9047, 01/2014, Volume 21, Issue 1, pp. 79 - 91
The immunogenic demise of cancer cells can be induced by various chemotherapeutics, such as anthracyclines and oxaliplatin, and provokes an immune response... 
quinacrine | apoptosis | U2OS cells | caspases | endoplasmic reticulum stress | Beclin 1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | AUTOPHAGY | CLEAVAGE | CHEMOTHERAPY | CELL BIOLOGY | CALRETICULIN EXPOSURE | PANNEXIN 1 | ASSAYS | FIND-ME SIGNAL | Connexins - antagonists & inhibitors | RNA-Binding Proteins - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Cell Death - immunology | rho-Associated Kinases - antagonists & inhibitors | Antineoplastic Agents - toxicity | DNA-Binding Proteins - metabolism | Lysosomes - metabolism | Lysosomal-Associated Membrane Protein 1 - genetics | Myosin Type II - metabolism | RNA Interference | rho-Associated Kinases - metabolism | Adenosine Triphosphate - metabolism | HMGB1 Protein - metabolism | Cell Membrane - metabolism | Cell Death - drug effects | RNA-Binding Proteins - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | Connexins - genetics | rho-Associated Kinases - genetics | Lysosomal-Associated Membrane Protein 1 - antagonists & inhibitors | Microtubule-Associated Proteins - antagonists & inhibitors | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Connexins - metabolism | Nerve Tissue Proteins - metabolism | Animals | Autophagy-Related Protein 5 | Cell Line, Tumor | Lysosomal-Associated Membrane Protein 1 - metabolism | Mice | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Original Paper
Journal Article
Science, ISSN 0036-8075, 3/2009, Volume 323, Issue 5922, pp. 1722 - 1725
Patten recognition receptors, which recognize pathogens or components of injured cells (danger), trigger activation of the innate immune system. Whether and... 
Receptors | Immune response | Cytokines | Hepatocytes | Splenocytes | Liver | Antibodies | Heat shock proteins | Ligands | Reports | Physiological regulation | SYSTEM | ACTIVATION | PROTEIN | AUTOIMMUNITY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MOBILITY GROUP BOX-1 | HMGB1 | HEAT-STABLE ANTIGEN | T-CELL GROWTH | ISCHEMIA-REPERFUSION | Liver - pathology | Immunoprecipitation | Receptors, Pattern Recognition - immunology | CD24 Antigen - metabolism | Dendritic Cells - immunology | Humans | HMGB1 Protein - immunology | Receptors, Antigen, B-Cell - metabolism | Necrosis - immunology | Lectins - metabolism | Receptors, Pattern Recognition - metabolism | Liver - immunology | HMGB1 Protein - chemistry | HMGB1 Protein - metabolism | CD24 Antigen - genetics | Protein Structure, Tertiary | Lipopolysaccharides - toxicity | Cytokines - metabolism | Signal Transduction | Acetaminophen - toxicity | Receptors, Cell Surface - metabolism | Mutant Proteins - metabolism | Inflammation - immunology | Immunity, Innate | HSP70 Heat-Shock Proteins - metabolism | Necrosis - chemically induced | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Transcription Factor RelA - metabolism | Mutant Proteins - chemistry | HSP90 Heat-Shock Proteins - metabolism | Mice | Research | Properties | Cell adhesion molecules | Proteins | Immunology | Cellular biology | Molecular biology | Rodents | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7413, pp. 670 - 674
The inflammasome regulates the release of caspase activation-dependent cytokines, including interleukin (IL)-1 beta, IL-18 and high-mobility group box 1... 
PATHWAYS | APOPTOSIS | ACID | PROTEIN-KINASE PKR | MULTIDISCIPLINARY SCIENCES | INFECTION | NLRP3 INFLAMMASOME | ELF2-ALPHA | STRESS | BINDING | SUBSTRATE RECOGNITION | Crystallins - metabolism | Interleukin-6 - analysis | Phosphorylation | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | eIF-2 Kinase - metabolism | Humans | Salmonella Infections - immunology | Male | Salmonella Infections - metabolism | HMGB1 Protein - secretion | Interleukin-1beta - blood | eIF-2 Kinase - deficiency | Adenosine Triphosphate - pharmacology | CARD Signaling Adaptor Proteins - metabolism | Transfection | Interleukin-6 - blood | Rotenone - pharmacology | Female | Membrane Proteins - metabolism | Escherichia coli - physiology | Macrophages, Peritoneal - drug effects | eIF-2 Kinase - genetics | Calcium-Binding Proteins - metabolism | Cell Line | Salmonella typhimurium - physiology | Interleukin-18 - blood | Salmonella typhimurium - immunology | Inflammasomes - agonists | Mice, Inbred C57BL | Peritonitis - metabolism | Cells, Cultured | Escherichia coli - immunology | Antigens, Bacterial - pharmacology | Escherichia coli Infections - metabolism | eIF-2 Kinase - antagonists & inhibitors | Apoptosis Regulatory Proteins - metabolism | Animals | Carrier Proteins - metabolism | Bacterial Toxins - pharmacology | Uric Acid - pharmacology | RNA, Double-Stranded - immunology | RNA, Double-Stranded - pharmacology | Escherichia coli Infections - immunology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Macrophages, Peritoneal - metabolism | HMGB1 Protein - blood | Physiological aspects | Chromosomal proteins | Research | Cytokines | Aluminum | Health aspects | Proteins | E coli | Pathogenesis | Plasmids | Bone marrow | Bacteria | Kinases
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 539 - 550
In contrast to microbially triggered inflammation, mechanisms promoting sterile inflammation remain poorly understood. Damage-associated molecular patterns... 
MEDICINE, RESEARCH & EXPERIMENTAL | DANGER SIGNALS | STERILE INFLAMMATION | CHROMATIN PROTEIN HMGB1 | IN-VIVO | SEPTIC SHOCK | MOBILITY GROUP BOX-1 | RECEPTOR | DEFICIENT MICE | CELL-DEATH | TRANSGENIC MICE | Acetaminophen - adverse effects | Inflammation - chemically induced | Leukocyte Elastase - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Tumor Necrosis Factor-alpha - genetics | Analgesics, Non-Narcotic - pharmacology | Hepatocytes - pathology | Hepatocytes - metabolism | Neutrophil Infiltration | fas Receptor - metabolism | Necrosis - pathology | HMGB1 Protein - genetics | Shock, Septic - metabolism | Inflammation - metabolism | Acetaminophen - pharmacology | Analgesics, Non-Narcotic - adverse effects | HMGB1 Protein - metabolism | fas Receptor - genetics | Chemical and Drug Induced Liver Injury - pathology | Neutrophils - metabolism | Receptor for Advanced Glycation End Products | Neutrophils - pathology | Shock, Septic - genetics | Shock, Septic - pathology | Lipopolysaccharides - toxicity | Macrophages - pathology | Shock, Septic - chemically induced | Leukocyte Elastase - genetics | Necrosis - metabolism | Chemical and Drug Induced Liver Injury - genetics | Mice, Knockout | Necrosis - chemically induced | Macrophages - metabolism | Animals | Chemical and Drug Induced Liver Injury - metabolism | Inflammation - genetics | Mice | Necrosis - genetics | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Physiological aspects | Causes of | Inflammation | Genetic aspects | Cell death | Necrosis | Chromosomal proteins | Mass spectrometry | Analysis | Proteins | Studies | Rodents | Mortality | Gangrene | Homeostasis | Mitochondrial DNA | Laboratory animals | Deoxyribonucleic acid--DNA | Apoptosis
Journal Article
Nature, ISSN 0028-0836, 11/2009, Volume 462, Issue 7269, pp. 99 - 103
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 28, pp. 12611 - 12616
Asbestos carcinogenesis has been linked to the release of cytokines and mutagenic reactive oxygen species (ROS) from inflammatory cells. Asbestos is cytotoxic... 
Actinomycin | Asbestos | Cell death | Secretion | Plasma cells | Inflammation | Macrophages | Carcinogenesis | Necrosis | Apoptosis | Mesothelioma | Biomarker | Tumor necrosis factor-alpha | Chemoprevention | TRANSFORMATION | POLY(ADP-RIBOSE) POLYMERASE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | CROCIDOLITE ASBESTOS | HMGB1 | biomarker | MAMMALIAN-CELLS | tumor necrosis factor-alpha | PATHOGENESIS | chemoprevention | NECROTIC CELLS | carcinogenesis | TNF-ALPHA | INHIBITORS | mesothelioma | Tumor Necrosis Factor-alpha - metabolism | Asbestos - metabolism | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Humans | Reactive Oxygen Species - pharmacology | Adenosine Diphosphate Ribose - metabolism | Adenosine Diphosphate Ribose - pharmacology | Carcinogens - metabolism | Asbestos - pharmacology | Pleural Neoplasms - metabolism | Inflammation - metabolism | Carcinogens - pharmacology | Cell Nucleus - metabolism | HMGB Proteins - pharmacology | HMGB1 Protein - pharmacology | HMGB1 Protein - metabolism | Cell Death | Mesocricetus | Female | HMGB Proteins - metabolism | Poly Adenosine Diphosphate Ribose - pharmacology | Epithelium - drug effects | Cricetinae | Cytokines - metabolism | Epithelium - metabolism | Hydrogen Peroxide - pharmacology | Necrosis - metabolism | Hydrogen Peroxide - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Macrophages - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Mesothelioma - metabolism | Poly(ADP-ribose) Polymerases - pharmacology | Cells - metabolism | Mice | Mice, Inbred BALB C | Cytokines - pharmacology | Prevention | Mesothelium | Chromosomal proteins | Research | Chemical properties | Health aspects | Reactive oxygen species | Transformation | Deposits | Hydrogen peroxide | Cytokines | Cytotoxicity | HMGB1 protein | Nuclei | Carcinogens | Tumor necrosis factor-a | ATP | Cytoplasm | Biological Sciences
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 06/2004, Volume 18, Issue 11, pp. 1272 - 1282
Necrosis has been considered a passive form of cell death in which the cell dies as a result of a bioenergetic catastrophe imposed by external conditions.... 
Alkylating DNA damage | Bax | PARP | Metabolism | Bak | Necrosis | p53 | APOPTOSIS | POLY(ADP-RIBOSE) POLYMERASE GENE | DEVELOPMENTAL BIOLOGY | RELEASE | alkylating DNA damage | BCL-2 | CHROMATIN PROTEIN | MICE RESISTANT | necrosis | GLUCOSE-METABOLISM | DISEASE | GENETICS & HEREDITY | metabolism | ENDOPLASMIC-RETICULUM | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Alkylating Agents - pharmacology | Molecular Sequence Data | Tumor Suppressor Protein p53 - genetics | Poly(ADP-ribose) Polymerases - drug effects | Inflammation - metabolism | DNA Damage - physiology | Mice, Mutant Strains | Adenosine Triphosphate - metabolism | Base Sequence | HMGB1 Protein - metabolism | Membrane Proteins - metabolism | NAD - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - drug effects | Macrophages - pathology | Membrane Proteins - genetics | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Proto-Oncogene Proteins - genetics | bcl-2-Associated X Protein | Enzyme Activation - drug effects | Fibroblasts - pathology | Tumor Suppressor Protein p53 - drug effects | Macrophages - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | bcl-2 Homologous Antagonist-Killer Protein | Membrane Proteins - drug effects | Macrophages - drug effects | Mice | Proto-Oncogene Proteins c-bcl-2 | Proteins | Research | Cell death | DNA repair | DNA damage | Research Papers
Journal Article