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hmgr (101) 101
index medicus (52) 52
biochemistry & molecular biology (38) 38
coenzyme-a reductase (38) 38
hydroxymethylglutaryl coa reductases - metabolism (36) 36
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3-hydroxy-3-methylglutaryl coenzyme a reductase (14) 14
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Journal of Experimental Medicine, ISSN 0022-1007, 01/2003, Volume 197, Issue 2, pp. 163 - 168
T lymphocytes expressing the T cell receptor (TCR)-γδ recognize unknown antigens on tumor cells. Here we identify metabolites of the mevalonate pathway as the... 
IPP | HMGR | Bisphosphonate drugs | Antigen recognition | Tumor antigen | antigen recognition | tumor antigen | bisphosphonate drugs
Journal Article
Zhongguo Zhongyao Zazhi, ISSN 1001-5302, 03/2019, Volume 44, Issue 5, pp. 942 - 947
Journal Article
Metabolic Engineering, ISSN 1096-7176, 07/2017, Volume 42, pp. 185 - 193
Journal Article
by Wang, Q and Yang, YB and Yang, XQ and Miao, CP and Li, YQ and Liu, SX and Luo, N and Ding, ZT and Zhao, LX
PHYTOCHEMISTRY, ISSN 0031-9422, 01/2018, Volume 145, pp. 146 - 152
Eight previously undescribed metabolites including of lovastatin analogues, a pair of diastereoisomers, a cyclopentenone dimer, and three polyketides were... 
Polyketide | Acetylcholinesterase inhibitor | MUTANTS | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Trichocomaceae | Aspergillus terreus | Lovastatin analogues | Inhibitor of HMGR | PLANT SCIENCES
Journal Article
International Food Research Journal, ISSN 1985-4668, 2018, Volume 25, Issue 3, pp. 1189 - 1196
Mentha piperita has been well known for its hypolipidemic activity. This prompted the present study to be carried out on a selected 12 phyto-constituents of... 
HMGR | Menthoside | Squalene synthase | Piperitoside | Eriodictyol | HMG CoA reductase | HMG CoA reductase (HMGR) | PROFILE | CHOLESTEROL | FRUIT | Menthoside piperitoside | FOOD SCIENCE & TECHNOLOGY | RATS | PIPERITA | STATINS | PEPPERMINT
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 01/2003, Volume 197, Issue 2, pp. 163 - 168
T lymphocytes expressing the T cell receptor (TCR)-gammadelta recognize unknown antigens on tumor cells. Here we identify metabolites of the mevalonate pathway... 
MEDICINE, RESEARCH & EXPERIMENTAL | STIMULATION | COENZYME-A REDUCTASE | AMINOBISPHOSPHONATES | NONPEPTIDE ANTIGENS | IPP | HMG-COA REDUCTASE | IMMUNOLOGY | bisphosphonate drugs | FARNESYL DIPHOSPHATE SYNTHASE | antigen recognition | tumor antigen | HMGR | INHIBITION | PATHWAY | PYROPHOSPHATE | LYMPHOMA
Journal Article
Phytochemistry, ISSN 0031-9422, 01/2018, Volume 145, pp. 146 - 152
Eight previously undescribed metabolites including of lovastatin analogues, a pair of diastereoisomers, a cyclopentenone dimer, and three polyketides were... 
Polyketide | Trichocomaceae | Acetylcholinesterase inhibitor | Aspergillus terreus | Lovastatin analogues | Inhibitor of HMGR | Metabolites | Diastereomers | Analysis | Acrylic acid | Lovastatin | Explosives | Antilipemic agents
Journal Article
Zhongguo Zhongyao Zazhi, ISSN 1001-5302, 05/2011, Volume 36, Issue 10, pp. 1275 - 1279
Journal Article
中草药:英文版, ISSN 1674-6384, 2016, Volume 8, Issue 4, pp. 344 - 351
Objective To clone and analyze 3-hydroxy-3-methylglutaryl coenzyme-A synthase(HMGS) and 3-hydroxy-3-methylglutaryl coenzyme-A reductase(HMGR) genes from Panax... 
cloning;HMGR;HMGS;Panax | analysis;gene | Araliaceae;bioinformatics | notoginseng | HMGS | Panax notoginseng | HMGR | gene cloning | bioinformatics analysis | Araliaceae
Journal Article
Acta Tropica, ISSN 0001-706X, 03/2016, Volume 155, pp. 113 - 123
Journal Article
Applied Biochemistry and Biotechnology, ISSN 0273-2289, 8/2017, Volume 182, Issue 4, pp. 1478 - 1490
The enzyme 3-hydroxy-3-methyl-glutaryl CoA reductase (HMGR) is a glycoprotein of the endoplasmic reticulum that participates in the mevalonate pathway, the... 
Biochemistry, general | EC .34 | Biotechnology | HMGR inhibitors | Chemistry | Antifungal | C andida glabrata | Recombinant HMGR | Heterologous expression | Candida glabrata | EC 1.1.1.34 | HMGRinhibitors | COENZYME-A REDUCTASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CATALYTIC PORTION | INHIBITION | GENE | CLONING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RESISTANCE | SIMVASTATIN | Temperature | Humans | Substrate Specificity | Molecular Targeted Therapy | Simvastatin - pharmacology | Hydroxymethylglutaryl CoA Reductases - metabolism | Protein Domains | Drug Evaluation, Preclinical | Hydroxymethylglutaryl CoA Reductases - chemistry | Recombinant Proteins - metabolism | Amino Acid Sequence | Biocatalysis | Hydroxymethylglutaryl-CoA Reductase Inhibitors - chemical synthesis | Enzyme Stability | Solubility | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Maltose-Binding Proteins - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Escherichia coli - genetics | Kinetics | Candida glabrata - genetics | Candida glabrata - enzymology | Hydroxymethylglutaryl CoA Reductases - genetics | Hydrogen-Ion Concentration | Enzymes | Hypercholesterolemia | Analysis | Escherichia coli | Phytosterols | Mycoses | Plant lipids | Health aspects | Statins | Sugars | Protein binding | Drugs | Ergosterol | Yeast | Mycosis | Simvastatin | Glycoprotein | Maltose-binding protein | Maltose | Drug development | Gene expression | Cholesterol | Fungi | Mevalonic acid | E coli | Temperature effects | Drug therapy | Endoplasmic reticulum | Recombinant | Reductase
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 02/2019, Volume 292, pp. 64 - 67
Due to increasing resistance of species to antifungal drugs, especially azoles, new drugs are needed. The proposed compounds and are analogous to α-asarone , a... 
HMGR | Ergosterol | Docking | C. glabrata | Antifungal | HMG-COA REDUCTASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BETA-ASARONE | PHARMACOLOGY | THERAPEUTIC TARGET | TOXICOLOGY | SIMVASTATIN | EXPRESSION
Journal Article
Acta Agronomica Sinica(China), ISSN 0496-3490, 2016, Volume 42, Issue 2, pp. 222 - 229
Journal Article