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JOURNAL OF THE NATIONAL CANCER INSTITUTE, ISSN 0027-8874, 10/2007, Volume 99, Issue 19, pp. 1490 - 1491
Journal Article
NATURE REVIEWS CANCER, ISSN 1474-175X, 12/2004, Volume 4, Issue 12, pp. 988 - 993
DNA hypermethylation in CpG-rich promoters is now recognized as a common feature of human neoplasia. However, the pathophysiology of hypermethylation (why,... 
COLON-CANCER | ABERRANT METHYLATION | PROMOTER HYPERMETHYLATION | HMLH1 PROMOTER | MULTIPLE GENES | HUMAN-DISEASE | DNA METHYLATION | SERRATED ADENOMAS | ONCOLOGY | COLORECTAL-CANCER | MICROSATELLITE INSTABILITY
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2019, Volume 25, Issue 1, pp. 378 - 389
Purpose: Colorectal cancers (CRCs) with microsatellite instability-high (MSI-H) status, due to mismatch repair deficiency, are associated with poor patient... 
FUSOBACTERIUM | SIGNATURES | ONCOLOGY | BRAF MUTATION | FREQUENT CAUSE | CONSENSUS MOLECULAR SUBTYPES | HMLH1 PROMOTER HYPERMETHYLATION | MISMATCH-REPAIR | COLON | INHIBITOR | SOMATIC MUTATIONS
Journal Article
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 05/2018, Volume 115, pp. 205 - 211
Sterigmatocystin (ST), being a precursor of aflatoxin, is categorized as Group 2B carcinogen. Our previous studies found that both mismatch repair (MMR)... 
G2 phase arrest | Signaling pathways | Sterigmatocystin | MAPK | hMLH1 | phase arrest
Journal Article
Journal Article
Journal Article
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, ISSN 1055-9965, 11/2008, Volume 17, Issue 11, pp. 3208 - 3215
Microsatellite instability (MSI) occurs in 10% to 20% of colorectal cancers (CRC) and has been attributed to both MLH1 promoter hypermethylation and germline... 
COLON-CANCER | HMLH1 PROMOTER | LYNCH-SYNDROME | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | GENE | ONCOLOGY | MICROSATELLITE INSTABILITY | PHENOTYPE | REPLICATION ERRORS | PROXIMAL COLON | EXPRESSION | AGE
Journal Article
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 09/2019, Volume 60, Issue 12, pp. 3943 - 3951
PURPOSE. Diabetes causes dysfunction in the retinal mitochondria and increases base mismatches in their DNA (mtDNA). The enzyme responsible for repairing the... 
MOLECULAR-MECHANISM | OXIDATIVE STRESS | METHYLATION | HYPERMETHYLATION | mutL homolog 1 | mitochondria | mismatch repair | HMLH1 | diabetic retinopathy | epigenetics | DNA methylation | MATRIX-METALLOPROTEINASE-9 | OPHTHALMOLOGY | PROMOTER | TRANSCRIPTIONAL REGULATION | EXPRESSION | Retinal Cell Biology
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 10/2011, Volume 56, Issue 10, pp. 2992 - 3004
DNA mismatch repair (MMR) deficiency results in a strong mutator phenotype and high-frequency microsatellite instability (MSI-H), which are the hallmarks of... 
Biochemistry, general | Prognosis | Medicine & Public Health | O 6 -methylguanine-DNA methyltransferase ( MGMT ) gene | Hepatology | Gastroenterology | Promoter CpG island hypermethylation | Oncology | Human mutS homolog 2 ( hMSH2 ) gene | Human mutL homolog 1 ( hMLH1 ) gene | Transplant Surgery | Esophageal squamous cell carcinoma (ESCC) | Human mutS homolog 2 (hMSH2) gene | methylguanine-DNA methyltransferase (MGMT) gene | Human mutL homolog 1 (hMLH1) gene | HMSH2 | HYPERMETHYLATION | MICROSATELLITE INSTABILITY | MGMT PROMOTER METHYLATION | MISMATCH REPAIR | HMLH1 | COLORECTAL-CARCINOMA | O-6-methylguanine-DNA methyltransferase (MGMT) gene | PROTEIN EXPRESSION | SQUAMOUS-CELL CARCINOMA | GASTROENTEROLOGY & HEPATOLOGY | HIGH-INCIDENCE AREA | MutL Protein Homolog 1 | Predictive Value of Tests | Carcinoma, Squamous Cell - genetics | Humans | DNA Repair Enzymes - genetics | Male | DNA Repair - genetics | MutS Homolog 2 Protein - metabolism | Case-Control Studies | Carcinoma, Squamous Cell - diagnosis | Carcinoma, Squamous Cell - mortality | Tumor Suppressor Proteins - genetics | DNA Repair Enzymes - metabolism | Esophageal Neoplasms - mortality | Esophageal Neoplasms - diagnosis | Female | Nuclear Proteins - genetics | Tumor Suppressor Proteins - metabolism | DNA Modification Methylases - metabolism | Kaplan-Meier Estimate | Esophagus - metabolism | Nuclear Proteins - metabolism | DNA Methylation - genetics | MutS Homolog 2 Protein - genetics | DNA Modification Methylases - genetics | Esophageal Neoplasms - genetics | Adaptor Proteins, Signal Transducing - genetics | CpG Islands - genetics | DNA, Neoplasm - genetics | Adaptor Proteins, Signal Transducing - metabolism | Squamous cell carcinoma | Transferases | Oncology, Experimental | Research | Chemotherapy | Anopheles | DNA | Genetic research | Genetic aspects | Methylation | Esophageal cancer | Tumors | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 07/2010, Volume 28, Issue 20, pp. 3380 - 3387
Journal Article
Nature Genetics, ISSN 1061-4036, 2009, Volume 41, Issue 1, pp. 112 - 117
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1355 - 1359
Journal Article