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SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2018, Volume 8
The transcription factor hepatocyte nuclear factor-1 alpha (HNF-1A) is involved in normal pancreas development and function. Rare variants in the HNF1A gene... 
TRANSCRIPTION FACTORS | INHIBITION | YOUNG | REPRESSION | HNF-1-ALPHA | MULTIDISCIPLINARY SCIENCES | MODY3 MUTATIONS | DEGRADATION | GENE ACTIVATION | EXPRESSION | SUMOYLATION
Journal Article
JAMA, ISSN 0098-7484, 06/2014, Volume 311, Issue 22, pp. 2305 - 2314
Journal Article
Diabetes, ISSN 0012-1797, 09/2018, Volume 67, Issue 9, pp. 1903 - 1907
There is wide variation in the age at diagnosis of diabetes in individuals with maturity-onset diabetes of the young (MODY) due to a mutation in the HNF1A... 
NUCLEAR FACTOR-1-ALPHA GENE | YOUNG | RARE VARIANTS | HNF-1-ALPHA | ENDOCRINOLOGY & METABOLISM | PHENOTYPE | RISK | MUTATIONS | POLYMORPHISM | ONSET | Phenotype | Gene mutations | Genetic variation | Genetic aspects | Diabetes | Diagnosis | Research
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 06/2009, Volume 29, Issue 11, pp. 2945 - 2959
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
BILE-ACID | HEPATOCYTE NUCLEAR FACTOR-1-ALPHA | HNF-1-ALPHA FUNCTION | GLUCOSE-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | GENE-EXPRESSION | FARNESOID-X RECEPTOR | BETA-CELL | BINDING-SITES | ALPHA-GENE | CELL BIOLOGY
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2005, Volume 115, Issue 4, pp. 1006 - 1015
Mutations in the gene encoding hepatocyte nuclear factor-4 alpha (HNF-4 alpha) result in maturity-onset diabetes of the young (MODY). To determine the... 
MEDICINE, RESEARCH & EXPERIMENTAL | I ALPHA-GENE | HNF-1-ALPHA FUNCTION | VISCERAL ENDODERM | PYRUVATE-KINASE | HYPERINSULINEMIC HYPOGLYCEMIA | K-ATP CHANNEL | PANCREATIC BETA-CELLS | KNOCKOUT MICE | EXPRESSION | NUCLEAR FACTOR-4-ALPHA GENE
Journal Article
The Journal of Biological Chemistry, ISSN 0021-9258, 08/2002, Volume 277, Issue 35, pp. 31909 - 31917
Sucrase-isomaltase (SI), an intestine-specific gene, is induced in the differentiated small intestinal villous epithelium during the suckling-weaning... 
VENTRAL MORPHOGENESIS | ACTIVATION | CRYPT-VILLUS AXIS | EPITHELIAL-CELLS | HNF-1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART TUBE FORMATION | RAT SMALL-INTESTINE | DIFFERENTIATION | EXPRESSION | TRANSGENIC MICE
Journal Article
Nature, ISSN 0028-0836, 12/1996, Volume 384, Issue 6608, pp. 455 - 458
THE disease non-insulin-dependent (type 2) diabetes mellitus (NIDDM) is characterized by abnormally high blood glucose resulting from a relative deficiency of... 
HNF1 | SUBTYPE | LOCALIZATION | HNF-1-ALPHA | MULTIDISCIPLINARY SCIENCES | CHROMOSOME 12Q | MELLITUS | CELL | Type 2 diabetes | Physiological aspects | Genetic aspects | Gene mutations | Liver cells
Journal Article
Diabetes Care, ISSN 0149-5992, 07/2005, Volume 28, Issue 7, pp. 1751 - 1756
β-Cell Dysfunction, Insulin Sensitivity, and Glycosuria Precede Diabetes in Hepatocyte Nuclear Factor-1α Mutation Carriers Amanda Stride , MRCP 1 , Sian Ellard... 
I ALPHA-GENE | HOMEOSTASIS MODEL ASSESSMENT | YOUNG | HNF-1-ALPHA | PUBERTAL STAGE | GLUCOSE | ENDOCRINOLOGY & METABOLISM | NONDIABETIC SUBJECTS | SECRETION | MODY3 | PATHOPHYSIOLOGY
Journal Article
Diabetes, ISSN 0012-1797, 12/2003, Volume 52, Issue 12, pp. 2989 - 2995
Hepatocyte nuclear factor-1alpha (HNF-1alpha) is a transcription factor that plays an important role in regulation of gene expression in pancreatic beta-cells,... 
DEPENDENT DIABETES-MELLITUS | HNF-1-ALPHA | METABOLISM | GLUCOSE | INSULIN-SECRETION | TRANSCRIPTION | ENDOCRINOLOGY & METABOLISM | YOUNG MODY1 | MICE | MUTATIONS | ALPHA-GENE
Journal Article
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 06/2009, Volume 94, Issue 6, pp. 1959 - 1965
Context: Mutations in the HNF 1A gene are the most common cause of maturity-onset diabetes of the young (MODY) in most populations. India currently has the... 
INSULIN | I ALPHA-GENE | MODY | HNF-1-ALPHA | ENDOCRINOLOGY & METABOLISM | MUTATIONS | MELLITUS | PROMOTER | HEPATOCYTE-NUCLEAR-FACTOR-1-ALPHA | GCK | EPIDEMIOLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2002, Volume 277, Issue 24, pp. 21361 - 21370
Claudin-2 is a structural component of tight junctions in the kidneys, liver, and intestine, but the mechanisms regulating its expression have not been... 
PHLORHIZIN HYDROLASE GENE | TIGHT JUNCTION STRANDS | HNF-1-ALPHA | EPITHELIAL-CELL LINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTESTINE-SPECIFIC TRANSCRIPTION | FACTOR-I | SUCRASE-ISOMALTASE GENE | NF-KAPPA-B | HOMEOBOX GENE | EXPRESSION
Journal Article
Current Diabetes Reports, ISSN 1534-4827, 3/2019, Volume 19, Issue 3, pp. 1 - 8
Journal Article
Journal Article
The Lancet, ISSN 0140-6736, 10/2003, Volume 362, Issue 9392, pp. 1275 - 1281
Type 2 diabetes shows evidence of underlying heterogeneity. No studies have assessed whether different causes for diabetes change the response to oral... 
MEDICINE, GENERAL & INTERNAL | HEPATOCYTE NUCLEAR FACTOR-1-ALPHA | HOMEOSTASIS MODEL ASSESSMENT | HNF-1-ALPHA FUNCTION | CONSORT STATEMENT | GLUCOSE | RANDOMIZED TRIALS | FACTOR-I | DOMINANT-NEGATIVE SUPPRESSION | INSULIN SENSITIVITY | BETA-CELL FUNCTION | Diabetes Mellitus - blood | Metformin - therapeutic use | Diabetes Mellitus - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Potassium Channels - physiology | Male | Sulfonylurea Receptors | ATP-Binding Cassette Transporters - physiology | Hyperglycemia - genetics | Gliclazide - therapeutic use | Fasting - blood | Adult | Female | Hepatocyte Nuclear Factor 1-beta | DNA-Binding Proteins | Hypoglycemic Agents - therapeutic use | Blood Glucose - analysis | Receptors, Drug - physiology | Metformin - pharmacology | Potassium Channels, Inwardly Rectifying | Diabetes Mellitus - drug therapy | Hepatocyte Nuclear Factor 1-alpha | Transcription Factors - genetics | Potassium Channels - drug effects | Hypoglycemic Agents - pharmacology | Nuclear Proteins | Diabetes Mellitus, Type 2 - blood | Receptors, Drug - drug effects | Hyperglycemia - blood | ATP-Binding Cassette Transporters - drug effects | Gliclazide - pharmacology | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hepatocyte Nuclear Factor 1 | Type 2 diabetes | Evaluation | Care and treatment | Hyperglycemia | Causes of | Physiological aspects | Genetic aspects | Diabetes | Sulfonylurea compounds | Hypoglycemic sulfonylureas | Genetics | Drug therapy | Medical treatment | Fasting | Sensitivity analysis | Intravenous administration | Diabetes mellitus | Tolbutamide | Pharmacology | Glucose | Metabolism | Hypoglycemia | Insulin | Patients | Sensitivity | Reduction | Motivation | Metabolites | Metformin | Mutation | Diabetes mellitus (non-insulin dependent) | Drug dosages
Journal Article