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Biomaterials, ISSN 0142-9612, 11/2018, Volume 182, pp. 299 - 311
Generation of human organoids from induced pluripotent stem cells (iPSCs) offers exciting possibilities for developmental biology, disease modelling and cell... 
Bioengineering | Liver stem cells | Biomimetic materials | Organogenesis | SYSTEM | STEM-CELLS | IN-VITRO | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | MODEL | Fibronectins | Drug resistance in microorganisms | Medical colleges | Developmental biology | Liver | Low density lipoproteins | Genetic transcription | Transforming growth factors | Sulfates | Proteins | Keratin | Polyethylene glycol | Analysis | Stem cells | Physiological aspects | Hepatitis C | Health aspects | PCA, principle component analysis | TGZ, Troglitazone | PEG, polyethylene glycol | Col, collagen | ICC, inverted colloidal crystal | LDLR, low-density lipoprotein receptor | ECM, extracellular matrix | HCV, hepatitis C virus | HSGP, heparin sulfate glycoprotein | CYC, cyclopamine | CK19, keratin 19 | RNA-seq, RNA-sequence | MRP2, multidrug resistance protein 1 | 2D, two-dimensional | HNF4a, hepatocyte nuclear factor 4-alpha | IH, iPSC derived hepatic progenitors | MSC, mesenchymal stem cell | iPSC, induced pluripotent stem cell | OCLN, occludin | CLDN1, claudin 1 | CLF, cholyl-lysyl-flourescence | RT-qPCR, reverse transcription-quantitative polymerase chain reaction | TGFβ, transforming growth factor beta | BSEP, bile-salt efflux pump | AFP, alpha-fetoprotein | FDA, food and drug administration | DE, iPSC derived definitive endoderm | H&E, haematoxylin and eosin | Fn, fibronectin | ZO-1, tight junction protein 1 | 3D, three-dimensional | ASGR1, asialoglycoprotein receptor 1 | ALB, albumin | SCARB1, scavenger receptor class B type 1 | Ln, laminin | ECAM, epithelial cell adhesion molecule | HUVEC, human umbilical endothelial cell
Journal Article
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 2012, Volume 27, Issue 4, pp. 430 - 438
Pregnane X receptor (PXR) mRNA was detected in HepG2 cells by RT-PCR, but not in human fetal liver (HFL) cells. CYP3A4 was induced by rifampicin (RIF),... 
drug-mediated induction | fetal liver | PXR | CYP3As | PGC1α | HNF4α | Fetal liver | PGC1a | HNF4a | Drug-mediated induction | DRUG-INTERACTIONS | GAMMA COACTIVATOR-1-ALPHA | NUCLEAR FACTOR 4-ALPHA | TRANSCRIPTIONAL COACTIVATOR | PREGNANE-X-RECEPTOR | HNF4 alpha | PGC1 alpha | GLUCOCORTICOID-RECEPTOR | HUMAN HEPATOCYTES | SIGNALING PATHWAY | CONSTITUTIVE ANDROSTANE RECEPTOR | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | Up-Regulation | Liver - enzymology | Receptors, Steroid - metabolism | Retinoid X Receptor alpha - metabolism | Humans | Promoter Regions, Genetic - drug effects | RNA, Messenger - metabolism | Liver - embryology | Nuclear Receptor Coactivator 1 - metabolism | CREB-Binding Protein - metabolism | Heat-Shock Proteins - genetics | Dexamethasone - pharmacology | Transfection | Cytochrome P-450 CYP3A - genetics | Liver - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Real-Time Polymerase Chain Reaction | Genes, Reporter | Cytochrome P-450 CYP3A - biosynthesis | Hepatocyte Nuclear Factor 4 - metabolism | Down-Regulation | Heat-Shock Proteins - metabolism | Clotrimazole - pharmacology | Enzyme Induction | Hepatocyte Nuclear Factor 4 - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Hep G2 Cells | Transcription Factors - metabolism | p300-CBP Transcription Factors - metabolism | Receptors, Steroid - genetics | Rifampin - pharmacology | Mifepristone - pharmacology | Pregnane X Receptor | Index Medicus
Journal Article