X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
hnpcc (1068) 1068
humans (897) 897
colorectal neoplasms, hereditary nonpolyposis - genetics (624) 624
female (584) 584
microsatellite instability (528) 528
colorectal cancer (526) 526
middle aged (500) 500
index medicus (496) 496
male (489) 489
oncology (471) 471
lynch syndrome (470) 470
adult (446) 446
nonpolyposis colorectal-cancer (388) 388
mutation (336) 336
aged (334) 334
genetics & heredity (309) 309
mutl protein homolog 1 (296) 296
colon-cancer (291) 291
risk (263) 263
genetic aspects (249) 249
cancer (246) 246
lynch-syndrome (242) 242
colorectal neoplasms, hereditary nonpolyposis - diagnosis (214) 214
nuclear proteins - genetics (211) 211
immunohistochemistry (209) 209
muts homolog 2 protein - genetics (209) 209
mlh1 (207) 207
msh2 (203) 203
colorectal neoplasms - genetics (200) 200
dna mismatch repair (199) 199
tumors (198) 198
pedigree (193) 193
mutations (187) 187
germ-line mutation (173) 173
mismatch repair (173) 173
adaptor proteins, signal transducing - genetics (172) 172
dna-binding proteins - genetics (168) 168
genetic predisposition to disease (168) 168
risk factors (164) 164
genetic testing (160) 160
families (156) 156
endometrial cancer (149) 149
gastroenterology & hepatology (149) 149
research (144) 144
colorectal neoplasms, hereditary nonpolyposis - pathology (141) 141
aged, 80 and over (134) 134
digestive system diseases (134) 134
surgery (129) 129
diagnosis (128) 128
carcinoma (126) 126
epidemiology (126) 126
genes (123) 123
gene mutations (120) 120
human genetics (120) 120
hereditary nonpolyposis colorectal cancer (118) 118
hmlh1 (118) 118
adaptor proteins, signal transducing (112) 112
genetics (112) 112
dna mutational analysis (111) 111
phenotype (110) 110
congenital, hereditary, and neonatal diseases and abnormalities (108) 108
pathology (107) 107
gene (99) 99
cancer research (98) 98
colorectal neoplasms, hereditary nonpolyposis - epidemiology (97) 97
biomedicine (95) 95
germline mutations (94) 94
health aspects (93) 93
surveillance (93) 93
familial adenomatous polyposis (92) 92
analysis (90) 90
dna mismatch repair - genetics (87) 87
dna repair (87) 87
neoplasm proteins - genetics (87) 87
muts homolog 2 protein (84) 84
hereditary (83) 83
neoplasms (82) 82
article (81) 81
mismatch repair genes (80) 80
adolescent (79) 79
proto-oncogene proteins - genetics (79) 79
medicine & public health (78) 78
hmsh2 (77) 77
bethesda guidelines (76) 76
nutritional and metabolic diseases (76) 76
biomedicine general (73) 73
carrier proteins (73) 73
colon cancer (73) 73
genetic counseling (72) 72
nuclear proteins (72) 72
endometrial neoplasms - genetics (71) 71
hereditary non-polyposis colorectal cancer (71) 71
guidelines (70) 70
young adult (70) 70
family (68) 68
genetic screening (66) 66
identification (65) 65
polymerase chain reaction (64) 64
criteria (63) 63
microsatellite repeats (63) 63
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1105) 1105
German (73) 73
French (55) 55
Japanese (24) 24
Spanish (6) 6
Italian (4) 4
Korean (4) 4
Czech (3) 3
Hungarian (2) 2
Chinese (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Genetics, ISSN 1061-4036, 2009, Volume 41, Issue 1, pp. 112 - 117
Journal Article
Gut, ISSN 0017-5749, 06/2013, Volume 62, Issue 6, pp. 812 - 823
Journal Article
Journal Article
JAMA, ISSN 0098-7484, 06/2011, Volume 305, Issue 22, pp. 2304 - 2310
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0121980
Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes, most frequently MLH1 and MSH2. Recently, MMR-deficient crypt foci (MMR-DCF)... 
COLON CANCERS | HNPCC | EVOLUTION | HEREDITARY | NONPOLYPOSIS COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | RISK | FRAMESHIFT MUTATIONS | TUMORS | GENETIC ALTERATIONS | MutL Protein Homolog 1 | Microsatellite Instability | Age Factors | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | MutS Homolog 2 Protein - genetics | Aberrant Crypt Foci - pathology | DNA-Binding Proteins - genetics | Aberrant Crypt Foci - genetics | Proteins - genetics | Young Adult | Adaptor Proteins, Signal Transducing - genetics | Adult | Aged | Nuclear Proteins - genetics | bcl-2-Associated X Protein - genetics | Intestinal Mucosa - pathology | Immunohistochemistry | Gene mutations | Colorectal cancer | Transformation | Bax protein | Endometrial cancer | Genes | Mucosa | Colorectal carcinoma | Biology | Microsatellite instability | Inactivation | DNA repair | Proteins | Alterations | Intestine | Mismatch repair | Cooperation | Gastroenterology | Tumorigenesis | Lesions | Repair | Deoxyribonucleic acid--DNA | Medical research | Microsatellites | Stability | Deactivation | MLH1 protein | MSH2 protein | Patients | Molecular chains | Pathology | Crypts | Protein expression | Transformations | Mutation | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Gut, ISSN 0017-5749, 07/2018, Volume 67, Issue 7, pp. 1306 - 1316
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2/2007, Volume 99, Issue 4, pp. 291 - 299
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 11/2009, Volume 33, Issue 11, pp. 1639 - 1645
The utility of immunohistochemical detection of DNA Mismatch repair proteins in screening colorectal cancer for hereditary nonpolyposis colorectal cancer... 
Immunohistochemistry | HNPCC | MSI | Microsatellite instability | DNA mismatch repair | Lynch syndrome | SURGERY | microsatellite instability | LYNCH-SYNDROME | REVISED BETHESDA GUIDELINES | TUMOR-CELLS | PATHOLOGY | CHROMOSOME 2 | MSH2 | MUTATION | immunohistochemistry | PROTEINS | EXPRESSION | Immunoenzyme Techniques - economics | MutL Protein Homolog 1 | Predictive Value of Tests | Prospective Studies | Humans | Middle Aged | DNA Repair Enzymes - genetics | MutS Homolog 2 Protein - metabolism | Neoplasm Proteins - metabolism | Mass Screening - methods | DNA-Binding Proteins - metabolism | Adenocarcinoma - metabolism | DNA Mismatch Repair - physiology | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | DNA Repair Enzymes - metabolism | Biomarkers, Tumor - metabolism | Adenocarcinoma - genetics | Mismatch Repair Endonuclease PMS2 | Retrospective Studies | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Mass Screening - economics | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Adenosine Triphosphatases - metabolism | Nuclear Proteins - metabolism | MutS Homolog 2 Protein - genetics | DNA-Binding Proteins - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | Adenocarcinoma - diagnosis | Immunoenzyme Techniques - methods | Adaptor Proteins, Signal Transducing - genetics | Adenosine Triphosphatases - genetics | Mutation | Adaptor Proteins, Signal Transducing - metabolism
Journal Article
BULLETIN DU CANCER, ISSN 0007-4551, 07/2019, Volume 106, Issue 7-8, pp. 647 - 655
Lynch syndrome is a genetic condition defined by a germline mutation of an MMR (MisMatch Repair) gene leading to a defective DNA MMR system. Therefore, it is... 
GENE-MUTATIONS | MANAGEMENT | MISMATCH REPAIR STATUS | MICROSATELLITE INSTABILITY | Colorectal cancer | GUIDELINES | RISK | COLON-CANCER | HNPCC | ONCOLOGY | BRAF MUTATION | Immunotherapy | COLORECTAL-CANCER | Lynch syndrome
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2018, Volume 143, Issue 1, pp. 139 - 150
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 3, pp. 604 - 613.e20
Journal Article