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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2013, Volume 110, Issue 11, pp. E986 - E995
Proapoptotic B-cell lymphoma 2 (BCL-2) antagonist/killer (BAK) and BCL-2-associated X (BAX) form toxic mitochondrial pores in response to cellular stress.... 
photocrosslinking | BCL-2 family | BCL-2 HOMOLOG | PROTEIN | MULTIDISCIPLINARY SCIENCES | apoptosis | STABILIZED ALPHA-HELICES | SAHB | BH3 DOMAIN | CYTOCHROME-C | X-RAY | stapled peptide | INHIBITOR | BINDING | MEMBRANE PERMEABILIZATION
Journal Article
Oncogene, ISSN 0950-9232, 06/2012, Volume 31, Issue 26, pp. 3177 - 3189
The intrinsic mitochondrial apoptotic pathway acts through two core pro-apoptotic proteins Bax (Bcl2-associated X protein) and Bak (Bcl2-antagonist/killer 1).... 
Bax | apoptosis | DKO | HCT116 | Bak | BH3-only | TRAIL | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | MEDIATED APOPTOSIS | BH3 MIMETIC ABT-737 | CELL BIOLOGY | NBK/BIK | GENE | ONCOLOGY | MITOCHONDRIAL PATHWAY | BCL-2 HOMOLOG BAX | GENETICS & HEREDITY | RESISTANCE | BH3-ONLY PROTEINS | Proto-Oncogene Proteins - metabolism | Apoptosis - drug effects | HCT116 Cells | Humans | bcl-2 Homologous Antagonist-Killer Protein - antagonists & inhibitors | bcl-2 Homologous Antagonist-Killer Protein - deficiency | bcl-2 Homologous Antagonist-Killer Protein - genetics | bcl-2-Associated X Protein - metabolism | Gene Knockout Techniques | Sulfonamides - pharmacology | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Piperazines - pharmacology | Apoptosis Regulatory Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Phenotype | Animals | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein | Fluorouracil - pharmacology | Mice | Gene Expression Regulation, Neoplastic - drug effects | bcl-2-Associated X Protein - deficiency | bcl-2-Associated X Protein - genetics | Cellular proteins | Colon cancer | Cancer cells | Development and progression | Research | Properties | Health aspects | Apoptosis | Proteins | Oncology | Cellular biology | Gene expression | Colorectal cancer | Drugs | Camptothecin | Mitochondria | Bax protein | Bcl-2 protein | Data processing | Colon | X protein | BAK protein | Mcl-1 protein
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2013, Volume 110, Issue 11, pp. E986 - E995
Proapoptotic B-cell lymphoma 2 (BCL-2) antagonist/killer (BAK) and BCL-2-associated X (BAX) form toxic mitochondrial pores in response to cellular stress.... 
photocrosslinking | MITOCHONDRIAL APOPTOSIS | BCL-2 family | PROTEIN | BCL-2 HOMOLOG BAK | MULTIDISCIPLINARY SCIENCES | apoptosis | BH3-ONLY LIGANDS | STABILIZED ALPHA-HELICES | SAHB | BH3 DOMAIN | CELL-DEATH | CYTOCHROME-C | X-RAY | stapled peptide | MEMBRANE PERMEABILIZATION
Journal Article
Molecular Cell, ISSN 1097-2765, 2000, Volume 6, Issue 6, pp. 1389 - 1399
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/1997, Volume 94, Issue 2, pp. 690 - 694
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2004, Volume 101, Issue 21, pp. 7988 - 7993
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/1995, Volume 14, Issue 22, pp. 5589 - 5596
Regulation of the cell death program involves physical interactions between different members of the Bcl‐2 family that either promote or suppress apoptosis.... 
Programmed cell death | Bcl-2 homolog | Bik | Apoptosis | APOPTOSIS | BCL-2 HOMOLOG | BIK | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHROMOSOMAL BREAKPOINT | FOLLICULAR LYMPHOMA | HOMOLOG | PROGRAMMED CELL DEATH | CELL BIOLOGY | BCL-2 | REGULATOR | GENE | CLONING
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 3/1999, Volume 144, Issue 5, pp. 903 - 914
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2001, Volume 276, Issue 36, pp. 34307 - 34317
Journal Article
Developmental Cell, ISSN 1534-5807, 2003, Volume 4, Issue 4, pp. 575 - 585
BAK is a pro-apoptotic BCL-2 family protein that localizes to mitochondria. Here we evaluate the function of BAK in several mouse models of neuronal injury... 
CYTOCHROME-C | APOPTOSIS | BCL-2 HOMOLOG BAK | IN-VIVO | KAINIC ACID | MECHANISMS | DEVELOPMENTAL BIOLOGY | DEFICIENT MICE | CASPASE ACTIVATION | BCL-X(L) | CELL-DEATH | CELL BIOLOGY | Central Nervous System Diseases - genetics | Neurons - pathology | Hippocampus - virology | Central Nervous System - metabolism | Age Factors | Synaptic Transmission - genetics | Apoptosis - genetics | Epilepsy - metabolism | Male | Neurotoxins - genetics | Excitatory Postsynaptic Potentials - drug effects | Central Nervous System Diseases - metabolism | Stroke - genetics | Kainic Acid | Central Nervous System Viral Diseases - genetics | Central Nervous System Viral Diseases - metabolism | Epilepsy - genetics | Synaptic Transmission - drug effects | Membrane Proteins - metabolism | Neurons - metabolism | Central Nervous System - virology | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Animals, Newborn | Neurons - virology | Sindbis Virus - genetics | Membrane Proteins - genetics | Neurodegenerative Diseases - genetics | Protein Structure, Tertiary - genetics | Neurodegenerative Diseases - metabolism | Genetic Vectors - genetics | Mice, Knockout | Hippocampus - metabolism | Stroke - metabolism | Animals | bcl-2 Homologous Antagonist-Killer Protein | Neurotoxins - metabolism | Mice | Central Nervous System - physiopathology | Hippocampus - physiopathology
Journal Article