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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2008, Volume 105, Issue 29, pp. 10095 - 10100
UL18 is a human cytomegalovirus class I MHC (MHCI) homolog that binds the host inhibitory receptor LIR-1 and the only known viral MHC homolog that presents... 
Molecules | Cytomegalovirus | Receptors | Molecular structure | Molecular interactions | Surface areas | Crystals | Natural killer cells | Down regulation | Crystal structure | X-ray crystallography | LIR-1 | Immune evasion | NATURAL-KILLER-CELLS | PROTEIN | CLASS-I HOMOLOG | RECOGNITION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | MAJOR HISTOCOMPATIBILITY COMPLEX | HLA-G | MOLECULES | x-ray crystallography | cytomegalovirus | immune evasion | HUMAN CYTOMEGALOVIRUS UL18 | Cytomegalovirus - chemistry | HLA-A2 Antigen - genetics | Receptors, Immunologic - chemistry | Receptors, Virus - metabolism | Humans | Multiprotein Complexes | Molecular Sequence Data | Crystallography, X-Ray | Antigens, CD - metabolism | Molecular Mimicry | Capsid Proteins - chemistry | Antigens, CD - chemistry | Amino Acid Sequence | Cytomegalovirus - genetics | Leukocyte Immunoglobulin-like Receptor B1 | Capsid Proteins - metabolism | Cytomegalovirus - metabolism | Models, Molecular | Glycosylation | Binding Sites - genetics | HLA-A2 Antigen - chemistry | Sequence Homology, Amino Acid | Protein Binding | HLA-A2 Antigen - metabolism | Receptors, Immunologic - metabolism | Capsid Proteins - genetics | Evaluation | Immunogenetics | Major histocompatibility complex | Cytomegalovirus infections | Development and progression | Genetic aspects | Research | Properties | Methods | Peptide bonds | Proteins | Carbohydrates | Peptides | Binding sites | Biological Sciences
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2004, Volume 172, Issue 9, pp. 5629 - 5637
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2007, Volume 178, Issue 6, pp. 3536 - 3543
NK and T cells are important for combating CMV infection. Some NK and T cells express leukocyte Ig-like receptor-1 (LIR-1), an inhibitory receptor recognizing... 
NATURAL-KILLER-CELLS | CYTOKINE PRODUCTION | HOMOLOG UL18 | INHIBITORY RECEPTOR | MAJOR HISTOCOMPATIBILITY COMPLEX | TRANSPLANT RECIPIENTS | IMMUNOLOGY | UP-REGULATION | CYTOTOXIC T-LYMPHOCYTES | VIRAL-INFECTION | MHC MOLECULES | Coculture Techniques | Humans | Middle Aged | Male | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - metabolism | Histocompatibility Antigens Class I - metabolism | Receptors, Immunologic - biosynthesis | T-Lymphocytes - metabolism | Capsid Proteins - immunology | Cytomegalovirus Infections - etiology | Killer Cells, Natural - immunology | Adult | Female | Receptors, Immunologic - immunology | Bystander Effect - immunology | Fibroblasts - metabolism | Fibroblasts - virology | Cells, Cultured | Histocompatibility Antigens Class I - immunology | Immune Tolerance | Cytomegalovirus - immunology | Lung Transplantation - immunology | Fibroblasts - immunology | T-Lymphocytes - immunology | Aged | Killer Cells, Natural - metabolism | Immunity, Cellular | Capsid Proteins - biosynthesis | Cytomegalovirus/immunology | Lung Transplantation/immunology | Histocompatibility Antigens Class I/immunology/metabolism | T-Lymphocytes/immunology/metabolism | Immunity | Natural/immunology/metabolism | Receptors | Cultured | Lungmedicin och allergi | Respiratory Medicine and Allergy | Cytomegalovirus Infections/etiology/immunology/metabolism | Cells | Fibroblasts/immunology/metabolism/virology | Cellular | Killer Cells | Bystander Effect/immunology | Capsid Proteins/biosynthesis/immunology | Immunologic/biosynthesis/immunology
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 10/2007, Volume 373, Issue 3, pp. 695 - 705
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2004, Volume 315, Issue 1, pp. 144 - 150
Human cytomegalovirus UL18, a MHC class I homologue, is known to serve as a natural killer cell (NK) decoy and to ligate NK inhibitory receptors to prevent... 
Natural killer cell | IFN-γ | Swine endothelial cell | Xenograft rejection | YT cell line | UL18 | ILT-2 | Human cytomegalovirus | NATURAL-KILLER-CELLS | CLASS-I HOMOLOG | BIOCHEMISTRY & MOLECULAR BIOLOGY | xenograft rejection | swine endothelial cell | MAJOR HISTOCOMPATIBILITY COMPLEX | human cytomegalovirus | HLA-G | HEAVY-CHAINS | BIOPHYSICS | IFN-gamma | INTERFERON-GAMMA | HYPERACUTE REJECTION | INHIBITORY RECEPTOR | ENDOPLASMIC-RETICULUM | natural killer cell | Endothelium, Vascular - cytology | Antigens, CD - immunology | Endothelium, Vascular - transplantation | Antigens, CD - biosynthesis | Humans | HLA Antigens - genetics | Flow Cytometry | Transfection | Receptors, Immunologic - biosynthesis | Swine | Capsid Proteins - immunology | Killer Cells, Natural - immunology | Cell Membrane - metabolism | Histocompatibility Antigens Class I - biosynthesis | Receptors, Immunologic - immunology | HLA Antigens - biosynthesis | Fluorescent Antibody Technique, Indirect | Endothelium, Vascular - immunology | Recombinant Proteins - metabolism | Cell Line | Transplantation, Heterologous - immunology | Leukocyte Immunoglobulin-like Receptor B1 | Capsid Proteins - metabolism | Interferon-gamma - secretion | Histocompatibility Antigens Class I - immunology | HLA Antigens - immunology | Histocompatibility Antigens Class I - genetics | Recombinant Proteins - genetics | HLA-G Antigens | Animals | Recombinant Proteins - immunology | Endothelium, Vascular - virology | Cell Membrane - immunology | Capsid Proteins - genetics | Cytotoxicity, Immunologic | Endothelium
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2016, Volume 196, Issue 3, pp. 947 - 955
`The human leukocyte Ig-like receptor family is part of the paired receptor system. The receptors are widely expressed by various immune cells, and new... 
HLA CLASS-I | HOMOLOG UL18 | CRYSTAL-STRUCTURE | PIR-B | INHIBITORY RECEPTOR | COMPETITIVE-BINDING | IMMUNOLOGY | IMMUNOGLOBULIN-LIKE RECEPTOR | MYELOMONOCYTIC CELLS | CUTTING EDGE | TRANSCRIPT 4 | Leukocytes - immunology | Ligands | Animals | Receptors, Immunologic - immunology | Humans | Histocompatibility Antigens Class I - immunology
Journal Article
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 10/2018, Volume 9, p. 2214
Human cytomegalovirus (HCMV) is under constant selective pressure from the immune system in vivo. Study of HCMV genes that have been lost in the absence of, or... 
NK cells | NK evasion | Genetic variation | HCMV | Immune modulation | NATURAL-KILLER-CELLS | DOWN-REGULATION | SURFACE EXPRESSION | genetic variation | NKG2D RECEPTOR | IMMUNOLOGY | HLA-E | CUTTING EDGE | HOMOLOG UL18 | HUMAN CYTOMEGALOVIRUS-INFECTION | INHIBITORY RECEPTOR | immune modulation | UP-REGULATION | Killer cells | Research | Gene expression | Cytomegaloviruses
Journal Article