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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2012, Volume 109, Issue 24, pp. 9454 - 9459
Journal Article
Genes and Development, ISSN 0890-9369, 08/2015, Volume 29, Issue 15, pp. 1593 - 1598
Journal Article
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 2017, Volume 27, Issue 6, pp. 1198 - 1203
Hrr25, a casein kinase 1 δ/ε homolog in budding yeast, is essential to set up mono-orientation of sister kinetochores during meiosis. Hrr25 kinase activity... 
homologous recombination | meiosis | Hrr25
Journal Article
BioTechniques, ISSN 0736-6205, 04/2019, Volume 66, Issue 4, pp. 198 - 201
The CRISPR/Cas9 system has recently emerged as a powerful tool for functional genomic studies and has been adopted for many organisms, including . Previously,... 
genome editing | CRISPR/Cas9 | homologous recombination
Journal Article
NATURE REVIEWS MOLECULAR CELL BIOLOGY, ISSN 1471-0072, 06/2016, Volume 17, Issue 6, pp. 337 - 349
The Fanconi anaemia pathway repairs DNA interstrand crosslinks (ICLs) in the genome. Our understanding of this complex pathway is still evolving, as new... 
COMPLEMENTATION GROUP-M | DNA-POLYMERASE-ZETA | FANCD2 MONOUBIQUITINATION | XERODERMA-PIGMENTOSUM | CROSS-LINK REPAIR | REPLICATION FORK RECOVERY | HOMOLOGOUS-RECOMBINATION | GENOME STABILITY | DOUBLE-STRAND BREAK | BONE-MARROW FAILURE | CELL BIOLOGY
Journal Article
by Li, J and Meng, XB and Zong, Y and Chen, KL and Zhang, HW and Liu, JX and Li, JY and Gao, CX
NATURE PLANTS, ISSN 2055-026X, 10/2016, Volume 2, Issue 10
Sequence-specific nucleases have been exploited to create targeted gene knockouts in various plants(1), but replacing a fragment and even obtaining gene... 
TRANSFORMATION | REPAIR | PLANTS | HOMOLOGOUS RECOMBINATION | CAS9 | GUIDE | GENOME | PLANT SCIENCES
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2019, Volume 116, Issue 1, pp. 337 - 337
Journal Article
Cell Reports, ISSN 2211-1247, 07/2013, Volume 4, Issue 1, pp. 220 - 228
Here, we present a simple and highly efficient method for generating and detecting mutations of any gene in through the use of the CRISPR/Cas9 system... 
IMMUNITY | REPAIR | GENE | HUMAN-CELLS | HOMOLOGOUS RECOMBINATION | IDENTIFICATION | CLEAVAGE | ZINC-FINGER NUCLEASES | GENOME | PROKARYOTES | CELL BIOLOGY
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, pp. 13274 - 13274
Targeted DNA double-strand breaks have been shown to significantly increase the frequency and precision of genome editing. In the past two decades, several... 
SYSTEM | RNA | DNA | MULTIDISCIPLINARY SCIENCES | DOUBLE-STRAND BREAKS | PLANTS | HOMOLOGOUS RECOMBINATION | TARGETED MUTAGENESIS | EFFICIENT | CAS9 RIBONUCLEOPROTEINS | NUCLEASES | Index Medicus
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 04/2013, Volume 201, Issue 3, pp. 395 - 408
Human DNA polymerase eta (Pol eta) is best known for its role in responding to UV irradiation-induced genome damage. We have recently observed that Pol. is... 
CELLS | FORK | POLYMERASE-ETA | COMMON | HOMOLOGOUS RECOMBINATION | STRESS | GENOME | DAMAGE | CHROMOSOMAL INSTABILITY | ATR | CELL BIOLOGY
Journal Article
Experimental Cell Research, ISSN 0014-4827, 08/2019, Volume 381, Issue 1, pp. 18 - 28
Telomerase-deficient cells of the budding yeast experience progressive telomere shortening and undergo senescence in a manner similar to that seen in cultured... 
Aging | Senescence | Checkpoint | Telomerase | Homologous recombination | Telomeres | Growth | Analysis
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2015, Volume 43, Issue 3, pp. e15 - e15
The emergence of new sequencing technologies has facilitated the use of bacterial whole genome alignments for evolutionary studies and outbreak analyses. These... 
CHROMOSOME | TRANSMISSION | STREPTOCOCCUS-PNEUMONIAE | EVOLUTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | POPULATION-STRUCTURE | GENE CONVERSION | HOMOLOGOUS RECOMBINATION | RESISTANT STAPHYLOCOCCUS-AUREUS | CLONE | EPIDEMIOLOGY | Genome, Bacterial | Algorithms | Recombination, Genetic | Bacteria - classification | Phylogeny | Sequence Analysis | Bacteria - genetics | Methods Online
Journal Article
Methods in Enzymology, ISSN 0076-6879, 01/2019, Volume 621, pp. 87 - 110
Heterologous expression of natural product biosynthetic gene clusters (BGCs) is a robust approach not only to decipher biosynthetic logic behind natural... 
Yeast homologous recombination | Biosynthesis | Natural products | Heterologous expression
Conference Proceeding
NATURE CELL BIOLOGY, ISSN 1465-7392, 09/2014, Volume 16, Issue 9, pp. 864 - 875
Epithelial-mesenchymal transition (EMT) is associated with characteristics of breast cancer stem cells, including chemoresistance and radioresistance. However,... 
EPITHELIAL-MESENCHYMAL TRANSITION | STEM-CELLS | METASTASIS | HISTONE H2AX PHOSPHORYLATION | CANCER CELLS | DOUBLE-STRAND BREAKS | CHECKPOINT | HOMOLOGOUS RECOMBINATION | IONIZING-RADIATION | MAMMALIAN-CELLS | CELL BIOLOGY
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/2014, Volume 111, Issue 26, pp. 9591 - 9596
Individuals homozygous for the C-C chemokine receptor type 5 gene with 32-bp deletions (CCR5 Delta 32) are resistant to HIV-1 infection. In this study, we... 
DEFINED FACTORS | RNA | SPECIFICITY | off-site target | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | TRANSDUCTION | cellular therapy | ZINC-FINGER NUCLEASES | homologous recombination | TTAA site | GENE CORRECTION | CAS9 | CCR5 | KNOCKDOWN
Journal Article
Annals of Oncology, ISSN 0923-7534, 08/2018, Volume 29, Issue 8, pp. 1609 - 1610
Journal Article
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 03/2009, Volume 66, Issue 6, pp. 1039 - 1056
Journal Article
DNA Repair, ISSN 1568-7864, 06/2019, Volume 78, pp. 91 - 101
Rad51 serves to maintain and protect integrity of the genome through its actions in DNA repair and replication fork protection. The active form of Rad51 is a... 
Rad51 | Dominant negative | BRCA2 | DNA repair | Homologous recombination
Journal Article
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