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The Journal of clinical investigation, ISSN 0021-9738, 12/2011, Volume 121, Issue 12, pp. 4655 - 4669
Parathyroid hormone-related protein (PTHrP) is a secreted factor expressed in almost all normal fetal and adult tissues... 
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Angiogenic Proteins - genetics | Cell Adhesion Molecules - genetics | Epithelial Cells - metabolism | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - immunology | Molecular Targeted Therapy | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - therapy | Mammary Glands, Animal - growth & development | Antibodies, Neutralizing - immunology | Antibodies, Neutralizing - therapeutic use | Mammary Neoplasms, Experimental - pathology | Apoptosis Regulatory Proteins - genetics | Cell Cycle Proteins - genetics | Female | Receptors, CXCR4 - genetics | Parathyroid Hormone-Related Protein - deficiency | Neoplasm Proteins - genetics | Angiogenic Proteins - biosynthesis | Apoptosis Regulatory Proteins - biosynthesis | Cell Adhesion Molecules - biosynthesis | Neoplasm Proteins - biosynthesis | Parathyroid Hormone-Related Protein - genetics | Cell Cycle Proteins - biosynthesis | Disease Progression | Mice, Knockout | Parathyroid Hormone-Related Protein - immunology | Xenograft Model Antitumor Assays | Neoplasm Metastasis - genetics | Receptors, CXCR4 - physiology | Animals | Mammary Glands, Animal - metabolism | Receptors, CXCR4 - biosynthesis | Breast Neoplasms - pathology | Parathyroid Hormone-Related Protein - physiology | Mice | Cellular proteins | Breast tumors | Parathyroid hormone | Development and progression | Metastasis | Research | Properties | Index Medicus | Abridged Index Medicus
Journal Article
Development (Cambridge), ISSN 1477-9129, 04/2008, Volume 135, Issue 11, pp. 1947 - 1956
Journal Article
Journal of molecular endocrinology, ISSN 0952-5041, 07/2017, Volume 59, Issue 1, pp. 13 - 27
Parathyroid hormone-related peptide (PTHrP) is associated with several human cancers such as colon carcinoma. This disease is a complex multistep process that... 
RSK | colon cancer cells | ERK1/2-p38MAPK | PTHrP | cell cycle migration | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Cyclin D1 - metabolism | Focal Adhesion Kinase 1 - genetics | Neoplasm Transplantation | Colonic Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Male | Phosphatidylinositol 3-Kinases - metabolism | Colonic Neoplasms - metabolism | Tumor Suppressor Protein p53 - genetics | MAP Kinase Signaling System - genetics | Injections, Intralesional | Mitogen-Activated Protein Kinase 1 - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Focal Adhesion Kinase 1 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Caco-2 Cells | Cell Survival - drug effects | Mitogen-Activated Protein Kinase 3 - genetics | HCT116 Cells | Cyclin-Dependent Kinase 6 - genetics | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | p38 Mitogen-Activated Protein Kinases - genetics | Cyclin-Dependent Kinase 6 - metabolism | Parathyroid Hormone-Related Protein - metabolism | Parathyroid Hormone-Related Protein - pharmacology | Phosphatidylinositol 3-Kinases - genetics | Cell Movement - drug effects | Animals | Cyclin D1 - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | Mice, Nude | Colonic Neoplasms - pathology | Mice | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, pp. e113606 - e113606
...), a DNA-binding, zinc-finger transcription factor, in cell proliferation of SCLC. EGR4 overexpression in HEK293T cells conferred significant upregulation of specific splice variants of the parathyroid hormone-related protein (PTHrP... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Interleukin-8 - genetics | NIH 3T3 Cells | Up-Regulation | Cell Proliferation | RANK Ligand - metabolism | Homeodomain Proteins - metabolism | Humans | Lung Neoplasms - metabolism | Transcriptional Activation | Lung Neoplasms - pathology | rab GTP-Binding Proteins - genetics | Small Cell Lung Carcinoma - metabolism | Chromatin Immunoprecipitation | Early Growth Response Transcription Factors - genetics | HEK293 Cells | Early Growth Response Transcription Factors - antagonists & inhibitors | Microfilament Proteins - metabolism | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Microfilament Proteins - genetics | rab GTP-Binding Proteins - metabolism | Interleukin-6 - genetics | Paracrine Communication | Parathyroid Hormone-Related Protein - genetics | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Parathyroid Hormone-Related Protein - metabolism | Homeodomain Proteins - genetics | RANK Ligand - genetics | Transcription Factors - metabolism | Small Cell Lung Carcinoma - pathology | Animals | Microfilament Proteins - antagonists & inhibitors | Early Growth Response Transcription Factors - metabolism | Homeodomain Proteins - antagonists & inhibitors | Cell Line, Tumor | rab GTP-Binding Proteins - antagonists & inhibitors | Mice | Growth | Genes | Analysis | Luciferase | Lung cancer, Small cell | Genetic aspects | Genetic transcription | Cell proliferation | Drugs | Alternative splicing | Target recognition | Gene regulation | Lung cancer | Oncology | Genomes | Metastasis | Drug development | Osteolysis | Metastases | Recruitment | Parathyroid hormone-related protein | Proteins | Bone growth | Biomedical materials | Cell growth | Antitumor agents | Rodents | Transcription activation | Biocompatibility | EGR-4 protein | Parathyroid | Deoxyribonucleic acid--DNA | Small cell lung carcinoma | Secretion | siRNA | Gene expression | Zinc | Medicine | Bone cancer | Depletion | Parathyroid hormone | Infertility | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Nature cell biology, ISSN 1476-4679, 06/2005, Volume 7, Issue 7, pp. 698 - 705
WSB-1 is a SOCS-box-containing WD-40 protein of unknown function that is induced by Hedgehog signalling in embryonic structures during chicken development... 
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Gene Expression - genetics | Growth Plate - embryology | Humans | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - physiology | Elongin | Trans-Activators - physiology | Hedgehog Proteins | RNA Interference | Iodide Peroxidase - metabolism | Trans-Activators - pharmacology | Protein Subunits - genetics | Amino Acid Sequence | Parathyroid Hormone-Related Protein - secretion | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Chick Embryo | Models, Biological | Mice | Iodide Peroxidase - genetics | Mutation | Ubiquitin-Protein Ligases - genetics | Immunoprecipitation | Thyroid Hormones - pharmacology | Gene Expression - drug effects | Molecular Sequence Data | Protein Subunits - metabolism | Chondrocytes - drug effects | In Situ Hybridization | Transfection | Trans-Activators - genetics | Tibia - metabolism | Protein Subunits - physiology | Cell Differentiation - physiology | Chondrocytes - metabolism | beta-Transducin Repeat-Containing Proteins - genetics | Proteins - physiology | Binding Sites - genetics | Growth Plate - metabolism | Tibia - drug effects | Proteins - genetics | Sequence Homology, Amino Acid | Tibia - cytology | Transcription Factors - metabolism | Two-Hybrid System Techniques | Animals | Proteins - metabolism | Cell Differentiation - drug effects | Thyroid Hormones - metabolism | Protein Binding | Physiological aspects | Research | Thyroid hormones | Gene expression | Ligases | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
Journal Article
PloS one, ISSN 1932-6203, 08/2011, Volume 6, Issue 8, pp. e23199 - e23199
p38 mitogen-activated protein kinase (MAPK) acts downstream in the signaling pathway that includes receptor activator of NF-kappa B (RANK... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Count | Humans | Tartrate-Resistant Acid Phosphatase | Male | Calcium - blood | Acid Phosphatase - metabolism | RANK Ligand - pharmacology | Isoenzymes - metabolism | Hypercalcemia - blood | p38 Mitogen-Activated Protein Kinases - metabolism | Pyrazoles - pharmacology | Osteoclasts - pathology | Hypercalcemia - pathology | NFATC Transcription Factors - metabolism | Osteogenesis - drug effects | Cells, Cultured | Proto-Oncogene Proteins c-fos - metabolism | Parathyroid Hormone-Related Protein - pharmacology | Bone Resorption - enzymology | Animals | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Bone Resorption - pathology | Mice | Osteoclasts - enzymology | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Osteoprotegerin - metabolism | Osteoclasts - drug effects | Bone resorption | Phosphatases | Macrophage colony stimulating factor | Hormones | T cells | Mitogens | Protein kinases | Transcription factors | Calcium | Homeostasis | NF-AT protein | Kinases | Macrophages | Osteoprotegerin | Parathyroid hormone-related protein | Proteins | Signal transduction | Calcium (blood) | Biomedical materials | Lymphocytes | Rodents | Acid resistance | Bone marrow | Tumor necrosis factor-TNF | Biocompatibility | Inhibition | TRANCE protein | Parathyroid | c-Fos protein | University graduates | NF-κB protein | Macrophage colony-stimulating factor | MAP kinase | Protein kinase inhibitors | Hypercalcemia | Medicine | Osteoclastogenesis | Signaling | Calvaria | Parathyroid hormone | Stromal cells | Orthopedics | Pancreatic cancer | Osteoclasts | Acid phosphatase (tartrate-resistant) | Acid phosphatase | Index Medicus
Journal Article