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Cell Cycle, ISSN 1538-4101, 06/2019, Volume 18, Issue 12, pp. 1407 - 1421
Heterochromatin Protein 1 α (HP1α) associates with members of the chromosome passenger complex (CPC) during mitosis, at centromeres where it is required for... 
HP1α | CBX5 | Aurora Kinase | chromosomal instability | LOCALIZATION | HP1 | SEGREGATION | CENTROMERE | IDENTIFICATION | CELL BIOLOGY | HP1 alpha | COLOCALIZATION | CHROMATIN PROTEIN HP1-ALPHA | HETEROCHROMATIN | CENP-A | BINDING
Journal Article
EMBO reports, ISSN 1469-221X, 07/2009, Volume 10, Issue 7, pp. 769 - 775
Trimethylation of lysine 9 in histone H3 (H3K9me3) enrichment is a characteristic of pericentric heterochromatin. The hypothesis of a stepwise mechanism to... 
HP1α | pericentric heterochromatin | CAF1 | SetDB1 | H3K9 methylation | METHYLATION | METHYLTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ZINC-FINGER PROTEINS | HP1 | LYSINE-9 | DNA-REPLICATION | CELL BIOLOGY | HP1 alpha | REPRESSION | HISTONE H3 | DROSOPHILA SU(VAR)3-9 | PROGRESSION | Scientific Report
Journal Article
Nature, ISSN 0028-0836, 04/2009, Volume 458, Issue 7242, pp. 1201 - 1204
Embryonic stem cells (ESCs) and other primitive stem cells of mice have been known for more than 30 years to potently block retrovirus replication. Infection... 
CARCINOMA-CELLS | HTLV-I | PROTEIN | TRIM28 | MULTIDISCIPLINARY SCIENCES | ASSAYS | MURINE LEUKEMIA-VIRUS | TRANSFER-RNA | PRIMER-BINDING-SITE | EXPRESSION | ZINC | Embryonic Stem Cells - metabolism | Humans | Leukemia Virus, Murine - genetics | Human T-lymphotropic virus 1 - growth & development | Tripartite Motif-Containing Protein 28 | RNA - genetics | DNA-Binding Proteins - metabolism | Retroviridae - genetics | Cell Differentiation | Embryonic Stem Cells - virology | Human T-lymphotropic virus 1 - genetics | Retroviridae - growth & development | Repressor Proteins - metabolism | Cell Line | Leukemia Virus, Murine - growth & development | DNA, Viral - metabolism | Gene Silencing | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - isolation & purification | Animals | Virus Replication | Gene Expression Regulation, Viral | Protein Binding | Mice | DNA, Viral - genetics | Physiological aspects | Genetic aspects | Research | DNA binding proteins | Embryonic stem cells | DNA | Proteins | Ultraviolet radiation | E coli | Protease inhibitors | Stem cells | Mass spectrometry | Experiments | Embryos | Deoxyribonucleic acid--DNA | Binding sites | Index Medicus | Primer binding site | KAP-1 | repressor binding site | murine leukemia virus | HP1β | HP1α | HP1γ | L1td1 | ZFP124 | silencing | ZFP809
Journal Article
Journal of molecular cell biology, ISSN 1674-2788, 12/2018, Volume 10, Issue 6, pp. 527 - 538
Heterochromatin protein 1 alpha (HP1 alpha) regulates chromatin specification and plasticity during cell fate decision. Different structural determinants... 
HP1α | LRIF1 | Centromere | Mitosis | Chromosome segregation | LOCALIZATION | centromere | HP1 | KINETOCHORE PROTEIN | HETEROCHROMATIN PROTEIN-1 | mitosis | CELL BIOLOGY | PHASE-SEPARATION | HP1 alpha | chromosome segregation | CHROMATIN PROTEIN HP1-ALPHA | TIP150 INTERACTS | BINDING | AURORA-B
Journal Article
International Journal of Oncology, ISSN 1019-6439, 12/2014, Volume 45, Issue 6, pp. 2541 - 2548
Heterochromatin protein 1 (HP1) is an epigenetic modifier of gene regulation and chromatin packing via binding to trimethylated histone H3 lysine 9 (H3K9). HP1... 
migration | HP1β | TIMP2 | MT1-MMP | MMP2 | cancer metastasis | Cancer metastasis | Migration | HETEROCHROMATIN PROTEIN-1 HP1 | ORAL-CANCER | IDENTIFICATION | MAMMALIAN-CELLS | HISTONES | BREAST-CANCER | MATRIX METALLOPROTEINASES | HP1 beta | ONCOLOGY | GENE-EXPRESSION | HP1(HS-ALPHA) | PROGRESSION | Studies | Proteins | Liver cancer | Bone cancer | Brain cancer | Leukemia | Melanoma | Colorectal cancer | Epigenetics | Breast cancer | Metastasis | Gene expression
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2018, Volume 503, Issue 4, pp. 2478 - 2484
Journal Article
Oncotarget, ISSN 1949-2553, 07/2019, Volume 10, Issue 46, pp. 4743 - 4760
Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and... 
Journal Article
Experimental and Therapeutic Medicine, ISSN 1792-0981, 05/2018, Volume 15, Issue 5, pp. 4271 - 4276
Increased expression of CRX3/HPl gamma, a core component of heterochromatin protein 1, has recently proved to be involved in human tumorigenesis and patient... 
Cbx3/HP1γ | Tongue neoplasms | Prognosis | MEDICINE, RESEARCH & EXPERIMENTAL | SUPPRESSOR | LUNG | ORAL-CANCER | HP1 | HETEROCHROMATIN PROTEIN-1 | prognosis | OVEREXPRESSION | Cbx3/HP1 gamma | GENE-EXPRESSION | tongue neoplasms | CANCER PROGRESSION | HP1-GAMMA
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2017, Volume 490, Issue 2, pp. 415 - 422
Journal Article
RNA Biology, ISSN 1547-6286, 06/2019, Volume 16, Issue 6, pp. 742 - 753
In the fission yeast Schizosaccharomyces pombe (S.pombe), heterochromatin domains are established and maintained by protein complexes that contain numerous RNA... 
Apatmer | S.pombe | Swi6 | SELEX | heterochromatin | S. pombe | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | SWI6/HP1 | BINDING | SCHIZOSACCHAROMYCES-POMBE | PROTEIN-1 HP1
Journal Article
Nature, ISSN 0028-0836, 10/2009, Volume 461, Issue 7265, pp. 819 - 822
Activation of Janus kinase 2 (JAK2) by chromosomal translocations or point mutations is a frequent event in haematological malignancies(1-6). JAK2 is a... 
CELLS | PROTEIN | MYELOPROLIFERATIVE DISORDERS | HEMATOPOIESIS | MULTIDISCIPLINARY SCIENCES | HP1 | MUTATIONS | LEUKEMIA | LYSINE 9 | DNA-REPLICATION
Journal Article