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The Journal of biological chemistry, ISSN 1083-351X, 2014, Volume 289, Issue 3, pp. 1402 - 1414
...) for the molecular chaperone heat shock protein 70 (Hsp70). There are six BAG family NEFs in humans, and each is thought to link Hsp70 to a distinct cellular pathway... 
Protein Complexes | Protein Misfolding | Cochaperones | HIGH-THROUGHPUT SCREEN | MOLECULAR CHAPERONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUALITY-CONTROL | Hsp40 | Protein Folding | HSP110 CHAPERONES | HEAT-SHOCK-PROTEIN | NEGATIVE REGULATOR | Isothermal Titration Calorimetry | J-DOMAIN | ATP HYDROLYSIS | STRUCTURAL BASIS | Molecular Chaperone | HSC70 CHAPERONE | ATPases | Protein-Protein Interactions | Adaptor Proteins, Signal Transducing - chemistry | Molecular Chaperones - metabolism | Transcription Factors - chemistry | Humans | Multiprotein Complexes - genetics | Molecular Chaperones - chemistry | DNA-Binding Proteins - metabolism | HSP110 Heat-Shock Proteins - chemistry | Multiprotein Complexes - metabolism | HSP70 Heat-Shock Proteins - chemistry | HSP40 Heat-Shock Proteins - chemistry | Recombinant Proteins - metabolism | HSP40 Heat-Shock Proteins - metabolism | HSP40 Heat-Shock Proteins - genetics | Molecular Chaperones - genetics | Recombinant Proteins - chemistry | HSP70 Heat-Shock Proteins - genetics | Recombinant Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | HSP70 Heat-Shock Proteins - metabolism | Transcription Factors - metabolism | HSP110 Heat-Shock Proteins - genetics | Multiprotein Complexes - chemistry | Apoptosis Regulatory Proteins | Adaptor Proteins, Signal Transducing - genetics | Adaptor Proteins, Signal Transducing - metabolism | HSP110 Heat-Shock Proteins - metabolism | Protein Binding - physiology | Protein Synthesis and Degradation
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2009, Volume 36, Issue 1, pp. 15 - 27
The multifunctional, stress-inducible molecular chaperone HSP70 has important roles in aiding protein folding and maintaining protein homeostasis... 
PROTEINS | CHEMBIO | CELLCYCLE | CANCER-CELLS | HSP70 | CHAPERONE-MEDIATED AUTOPHAGY | NEGATIVE REGULATION | LYSOSOMAL MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEAT-SHOCK RESPONSE | APAF-1 APOPTOSOME | P53 PROTEINS | P62 | CELL-DEATH | CELL BIOLOGY | HSP70 Heat-Shock Proteins - antagonists & inhibitors | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Humans | NF-kappa B - metabolism | Cathepsin L - metabolism | Autophagy - drug effects | DNA-Binding Proteins - metabolism | Caspases - metabolism | Lysosomes - metabolism | Protein Binding - drug effects | Lymphoma - pathology | Protein Interaction Domains and Motifs | Cell Death - drug effects | Lysosomes - drug effects | Cell Survival - drug effects | HSP40 Heat-Shock Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | HSP70 Heat-Shock Proteins - genetics | Mice, Transgenic | Mice, Inbred Strains | Sulfonamides - pharmacology | Apoptotic Protease-Activating Factor 1 - metabolism | HSP70 Heat-Shock Proteins - metabolism | Transcription Factors - metabolism | Animals | Sulfonamides - therapeutic use | Lymphoma - prevention & control | Sulfonamides - metabolism | Cell Line, Tumor | Mice | Adaptor Proteins, Signal Transducing - metabolism | Protein Multimerization - drug effects | Protein Binding - physiology | Proteins | Heat shock proteins | Analysis | Tumors
Journal Article
Molecular cell, ISSN 1097-2765, 2016, Volume 63, Issue 5, pp. 739 - 752
Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 2015, Volume 11, Issue 5, pp. 759 - 769
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 10, p. e26319
... ATPase that collaborates with Hsp70 and Hsp40 to promote protein disaggregation and reactivation... 
YEAST | IN-VITRO | CAENORHABDITIS-ELEGANS | MOLECULAR CHAPERONES | MULTIDISCIPLINARY SCIENCES | AGGREGATED PROTEINS | ALPHA-SYNUCLEIN | SACCHAROMYCES-CEREVISIAE | HUNTINGTONS-DISEASE | HEAT-SHOCK-PROTEIN | NUCLEOTIDE EXCHANGE FACTORS | Mammals - metabolism | HSP40 Heat-Shock Proteins - metabolism | Biocatalysis | Humans | Adenosine Triphosphatases - metabolism | Rats | Substrate Specificity | HSP70 Heat-Shock Proteins - metabolism | HSP110 Heat-Shock Proteins - chemistry | Hydrolysis | Saccharomyces cerevisiae - metabolism | Cytosol - enzymology | Animals | Amyloid - metabolism | Cell-Free System | Adenosine Triphosphate - metabolism | Protein Structure, Quaternary | Saccharomyces cerevisiae Proteins - metabolism | Conserved Sequence | Protein Binding | HSP70 Heat-Shock Proteins - chemistry | HeLa Cells | HSP110 Heat-Shock Proteins - metabolism | HSP40 Heat-Shock Proteins - chemistry | Heat shock proteins | Prions | Cells | Adenosine triphosphatase | Baking yeast | Parkinson's disease | Cell-free system | Homology | Activation | Biochemistry | Kinases | Synuclein | Cytosol | Machinery | Machinery and equipment | Fungi | Protein folding | Bacteria | Amyloid | Trends | Prion protein | Movement disorders | Adenosine triphosphate | Protozoa | Neurodegenerative diseases | Disaggregation | Hsp70 protein | Hsp40 protein | Mammals | Substrates | Aggregates | Hsc70 protein | Mutation | Alzheimers disease | Endoplasmic reticulum | ATP
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2018, Volume 37, Issue 2, pp. 282 - 299
... and in vivo assays, we have identified a trimeric chaperone complex (Hsc70, Hsp110, and J‐protein) that completely suppresses fibrilization of HttExon1Q48... 
suppression | disaggregation | molecular chaperones | HttpolyQ | NPCs | EXPANDED HUNTINGTIN | HSP70 | PROTEIN AGGREGATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | TOXICITY | CELLULAR-MODEL | CELL BIOLOGY | DISEASE | POLYGLUTAMINE AGGREGATION | STRESS | ATP | Neurons - pathology | HSC70 Heat-Shock Proteins - metabolism | Humans | Huntington Disease - pathology | Multiprotein Complexes - genetics | HSP110 Heat-Shock Proteins - chemistry | Multiprotein Complexes - metabolism | Protein Aggregation, Pathological - pathology | HEK293 Cells | Neurons - metabolism | HSP40 Heat-Shock Proteins - chemistry | Protein Aggregation, Pathological - genetics | HSC70 Heat-Shock Proteins - genetics | HSP40 Heat-Shock Proteins - metabolism | HSP40 Heat-Shock Proteins - genetics | Huntingtin Protein - metabolism | Huntington Disease - metabolism | Huntingtin Protein - chemistry | Caenorhabditis elegans | HSP110 Heat-Shock Proteins - genetics | Multiprotein Complexes - chemistry | Animals | HSC70 Heat-Shock Proteins - chemistry | Huntington Disease - genetics | Huntingtin Protein - genetics | HSP110 Heat-Shock Proteins - metabolism | Protein Aggregation, Pathological - metabolism | Huntingtons disease | Polyglutamine | Huntingtin | Neurodegenerative diseases | Fibrils | Trinucleotide repeats | Disaggregation | Agglomeration | Chaperones | Huntington's disease | Mammalian cells | Proteins | Fibrillogenesis | Hsc70 protein | Neuroscience | Protein Biosynthesis & Quality Control | Molecular Biology of Disease
Journal Article
by Lu, X and Kakkar, V
Current Medicinal Chemistry, ISSN 0929-8673, 04/2010, Volume 17, Issue 10, pp. 957 - 973
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148517
.... Molecular chaperones of the heat shock protein (Hsp) family are prominent members of the exportome, including a number of Hsp40s and a Hsp70... 
HSP70 CHAPERONES | J PROTEINS | DNAJ | YEAST HSP40 | PLASMODIUM-FALCIPARUM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | MOLECULAR CHAPERONE | DIMERIZATION | PARASITE | Protein Aggregates | Molecular Chaperones - metabolism | Humans | Molecular Chaperones - chemistry | Recombinant Proteins | Protozoan Proteins - genetics | Thiosulfate Sulfurtransferase - metabolism | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | HSP70 Heat-Shock Proteins - chemistry | HSP40 Heat-Shock Proteins - chemistry | HSP40 Heat-Shock Proteins - metabolism | HSP40 Heat-Shock Proteins - genetics | HSP40 Heat-Shock Proteins - isolation & purification | Molecular Chaperones - genetics | Adenosine Triphosphatases - metabolism | HSP70 Heat-Shock Proteins - genetics | HSP70 Heat-Shock Proteins - metabolism | Malaria, Falciparum - parasitology | Protozoan Proteins - isolation & purification | Protein Binding | HSP70 Heat-Shock Proteins - isolation & purification | Kinetics | Molecular Chaperones - isolation & purification | Plasmodium falciparum | Malaria | Heat shock proteins | Physiological aspects | Causes of | Genetic aspects | Research | Vector-borne diseases | Biotechnology | Yeast | Erythrocytes | Biochemistry | Hsp70 protein | Chaperones | Parasites | Hsp40 protein | Drug resistance | Cytosol | Proteins | Red blood cells | E coli | Protein folding | Rhodanese | Protein transport | Human behavior | Adenosine triphosphatase | Heat shock | Exports
Journal Article