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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2019, Volume 514, Issue 3, pp. 933 - 939
Cancer-associated fibroblasts comprise the major stromal cell populations in gastric cancer, which is a significant contributor to cancer-related death... 
HTRA1 | Cancer-associated fibroblasts | Gastric cancer | Transdifferentiation
Journal Article
by Grassmann, Felix and Heid, Iris M and Weber, Bernhard H. F and Fritsche, L.G and Igl, W and Bailey, J.N and Grassmann, F and Sengupta, S and Bragg-Gresham, J.L and Burdon, K.P and Hebbring, S.J and Wen, C and Gorski, M and Kim, I.K and Cho, D and Zack, D and Souied, E and Scholl, H.P and Bala, E and Lee, K.E and Hunter, D.J and Sardell, R.J and Mitchell, P and Merriam, J.E and Cipriani, V and Hoffman, J.D and Schick, T and Lechanteur, Y.T and Guymer, R.H and Johnson, M.P and Jiang, Y and Stanton, C.M and Buitendijk, G.H and Zhan, X and Kwong, A.M and Boleda, A and Brooks, M and Gieser, L and Ratnapriya, R and Branham, K.E and Foerster, J.R and Heckenlively, J.R and Othman, M.I and Vote, B.J and Liang, H.H and Souzeau, E and McAllister, I.L and Isaacs, T and Hall, J and Lake, S and Mackey, D.A and Constable, I.J and Craig, J.E and Kitchner, T.E and Yang, Z and Su, Z and Luo, H and Chen, D and Ouyang, H and Flagg, K and Lin, D and Mao, G and Ferreyra, H and Stark, K and von Strachwitz, C.N and Wolf, A and Brandl, C and Rudolph, G and Olden, M and Morrison, M.A and Morgan, D.J and Schu, M and Ahn, J and Silvestri, G and Tsironi, E.E and Park, K.H and Farrer, L.A and Orlin, A and Brucker, A and Li, M and Curcio, C.A and Mohand-Saïd, S and Sahel, J.A and Audo, I and Benchaboune, M and Cree, A.J and Rennie, C.A and Goverdhan, S.V and Grunin, M and Hagbi-Levi, S and Campochiaro, P and Katsanis, N and Holz, F.G and Blond, F and Blanché, H and Deleuze, J.F and Igo, R.P and Truitt, B and Peachey, N.S and Meuer, S.M and ... and Int AMD Genomics Consortium IAMDGC and International AMD Genomics Consortium (IAMDGC)
Genetics, ISSN 0016-6731, 02/2017, Volume 205, Issue 2, pp. 919 - 924
Journal Article
European Journal of Histochemistry, ISSN 1121-760X, 12/2015, Volume 59, Issue 4, pp. 268 - 273
Journal Article
Journal of Neuropathology & Experimental Neurology, ISSN 0022-3069, 11/2016, Volume 75, Issue 11, pp. 1020 - 1030
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is a nonhypertensive hereditary cerebral small vessel... 
Stroke | Aterosclerosis | Autopsy | CARASIL | Genetic | HTRA1 | TGF-b1 | Vascular | POPULATION | CELLS | TGF-beta 1 | PATHOLOGY | HTRA1 GENE | NEUROSCIENCES | CLINICAL NEUROLOGY | CADASIL | Atherosclerosis | MUTATION | DISEASE | PATIENT | ALOPECIA
Journal Article
BMC Cancer, ISSN 1471-2407, 02/2018, Volume 18, Issue 1, pp. 143 - 143
Background: HtrA1 is expressed in a variety of normal human tissues and seems to be involved in numerous physiological processes as well as tumorigenesis. This... 
HtrA1 | Cancer | Meta-analysis | ONCOLOGY | BIAS | SERINE-PROTEASE HTRA1 | GENES | EXPRESSION | CHEMOTHERAPY | FAMILY | Development and progression | Messenger RNA | Research | Biological markers | Index Medicus
Journal Article
Cellular and Molecular Biology, ISSN 0145-5680, 2018, Volume 64, Issue 1, pp. 107 - 110
Scar treatments are considered a major issue in the plastic surgery field. Activation of the transforming growth factor-β (TGF-β)-mediated signaling pathway... 
HTRA1 | Smad2 | TGF-β | Pathological scar
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2017, Volume 18, Issue 9, p. 1842
As in humans, osteoarthritis (OA) causes considerable economic loss to the equine industry. New hopes for cartilage repair have emerged with the... 
Col1a1 | Chondrocyte | Tissue engineering | Dedifferentiation | Hypoxia | Matrix-associated autologous chondrocyte implantation (MACI) | HtrA1 | BMP-2 | Equine model | Type II collagen | SiRNA | CARTILAGE REPAIR | OSTEOARTHRITIC CHONDROCYTES | matrix-associated autologous chondrocyte implantation (MACI) | hypoxia | tissue engineering | BONE MORPHOGENETIC PROTEIN-2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | SERINE-PROTEASE HTRA1 | dedifferentiation | siRNA | COLLAGEN SPONGE SCAFFOLDS | HUMAN ARTICULAR CHONDROCYTES | CHEMISTRY, MULTIDISCIPLINARY | MESENCHYMAL STEM-CELLS | CHONDROGENIC EXPRESSION | type II collagen | equine model | chondrocyte | II COLLAGEN | TERM-FOLLOW-UP | Bone Morphogenetic Protein 2 - pharmacology | RNA, Small Interfering - genetics | Chondrocytes - cytology | Collagen Type I - metabolism | Cartilage, Articular - cytology | Collagen Type III - metabolism | Extracellular Matrix - metabolism | Cell Differentiation - genetics | Chondrocytes - drug effects | Phenotype | Animals | RNA Interference | Cartilage, Articular - metabolism | Cell Differentiation - drug effects | Bone Morphogenetic Protein 2 - metabolism | Biomarkers | Horses | Cell Culture Techniques | Cell Hypoxia - genetics | Chondrocytes - metabolism | Tissue Engineering | Cell culture | Therapy | Collagen (type I) | Clinical trials | Cartilage | Biomedical materials | Bone morphogenetic proteins | Extracellular matrix | Biocompatibility | Medical research | Bone morphogenetic protein 2 | RNA-mediated interference | Interference | Implantation | Data processing | Ribonucleic acids | Collagen | Chondrocytes | Autologous chondrocyte implantation | Osteoarthritis | Three dimensional models | Cartilage diseases | Index Medicus | Life Sciences
Journal Article
by Teoh, SSY and Zhao, M and Wang, Y and Chen, Q and Nie, GY
PLACENTA, ISSN 0143-4004, 09/2015, Volume 36, Issue 9, pp. 990 - 995
Introduction: HtrA1 (high temperature requirement Al) is a serine protease of the HtrA family. We have previously shown that the placenta expresses the highest... 
PATHWAYS | SERINE-PROTEASE HTRA1 | PLACENTA | SOLUBLE ENDOGLIN | DEVELOPMENTAL BIOLOGY | LEVEL | FAMILY | OBSTETRICS & GYNECOLOGY | Pregnancy | REPRODUCTIVE BIOLOGY | PREGNANCIES | Enzyme linked immunosorbent assay | Preeclampsia | Serine protease | HtrA1 | UP-REGULATION | EXPRESSION
Journal Article
by Li, DP and Yue, JW and Wu, Y and Barnie, PA and Wu, YM
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, ISSN 1936-2625, 2018, Volume 11, Issue 2, pp. 998 - 1008
Background: There are few studies that have identified the potential role of a high temperature requirement A1 (HtrA1) in intervertebral disc degeneration... 
NUCLEUS PULPOSUS | SERINE-PROTEASE HTRA1 | PATHOLOGY | AND-13 | intervertebral disc degeneration | A1 HTRA1 | ONCOLOGY | ROLES | Intervertebral disc | OSTEOSARCOMA | THERAPIES | matrix metalloproteinases | NF-KAPPA-B | extracellular matrix | ERK
Journal Article
Endocrine Regulations, ISSN 1336-0329, 01/2019, Volume 53, Issue 1, pp. 34 - 45
The development of obesity and its metabolic complications is associated with dys-regulation of various intrinsic mechanisms, which control basic metabolic... 
IGFBPs | HTRA1 | IGFs | blood | insulin resistance | obesity | mRNA expression
Journal Article
by Li, R and Zhang, Q
JOURNAL OF MOLECULAR HISTOLOGY, ISSN 1567-2379, 04/2015, Volume 46, Issue 2, pp. 137 - 144
Periodontal ligament cells (PDLCs) in periodontal ligament (PDL) can differentiate into osteoblasts, while physiologically PDL remains non-mineralized space... 
Human periodontal ligament cells (hPDLCs) | STEM-CELLS | TGF-beta 1 | REGENERATION | SERINE-PROTEASE HTRA1 | DISEASE | High-temperature requirement protein A1 (HtrA1) | Osteogenic differentiation | Lentivirus | BETA | CELL BIOLOGY
Journal Article
Journal of Xi'an Jiaotong University (Medical Sciences), ISSN 1671-8259, 11/2015, Volume 36, Issue 6, pp. 749 - 757
Journal Article