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Journal Article
Journal Article
Lung Cancer, ISSN 0169-5002, 2012, Volume 77, Issue 2, pp. 427 - 432
Abstract Background and purpose : Cisplatin is the major agent in the standard first-line chemotherapy for NSCLC. However, only a small portion of patients... 
Hematology, Oncology and Palliative Medicine | Pulmonary/Respiratory | Efficacy | Chemotherapy | Biomarker | Dihydrodiol dehydrogenase 2 (DDH2) | Proteomics | Non-small cell lung cancer | TUMOR-CELLS | DRUG-RESISTANCE | INDUCTION | CELL LUNG-CANCER | OVEREXPRESSION | ONCOLOGY | POTE | ROLES | RESPIRATORY SYSTEM | OVARIAN | Lung Neoplasms - drug therapy | Prognosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - toxicity | Cisplatin - toxicity | Biomarkers, Tumor - metabolism | Adult | Female | Hydroxysteroid Dehydrogenases - metabolism | Transcription, Genetic | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - enzymology | Cisplatin - pharmacology | Hydroxysteroid Dehydrogenases - genetics | Drug Resistance, Neoplasm - genetics | Cisplatin - therapeutic use | Cell Line, Tumor | Aged | Biomarkers, Tumor - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Neoplasm Staging | Immunohistochemistry | Medical research | Medical colleges | Care and treatment | Lung cancer | Development and progression | Lung cancer, Non-small cell | Antineoplastic agents | Cisplatin | Proteins | Antimitotic agents | Medicine, Experimental | Enzyme-linked immunosorbent assay | Cancer | Index Medicus
Journal Article
Journal Article
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 5/2008, Volume 61, Issue 6, pp. 979 - 987
We have previously demonstrated that overexpression of dihydrodiol dehydrogenase isoform 1 (DDH1) or DDH2 leads to the induction of drug resistance to platinum... 
Reactive oxygen species | Biomedicine | Dihydrodiol dehydrogenases | Human ovarian carcinoma cells | Oncology | Cancer Research | Cisplatin resistance | Pharmacology/Toxicology | OXIDATIVE STRESS | INCREASED EXPRESSION | cisplatin resistance | POLYCYCLIC AROMATIC-HYDROCARBONS | human ovarian carcinoma cells | SENSITIVITY | TUMOR-CELLS | INDUCTION | ALDO-KETO REDUCTASE | 3-ALPHA-HYDROXYSTEROID-DIHYDRODIOL DEHYDROGENASE | ONCOLOGY | reactive oxygen species | PHARMACOLOGY & PHARMACY | CIS-DIAMMINEDICHLOROPLATINUM(II) ACCUMULATION | MODULATION | dihydrodiol dehydrogenases | Reactive Oxygen Species - metabolism | Humans | Ovarian Neoplasms - pathology | Drug Resistance, Neoplasm | Alcohol Oxidoreductases - biosynthesis | Alcohol Oxidoreductases - physiology | Esterases - biosynthesis | Heme Oxygenase (Decyclizing) - biosynthesis | Enzyme Induction - drug effects | Female | tert-Butylhydroperoxide - pharmacology | Antineoplastic Agents - pharmacology | Clone Cells | Heme Oxygenase (Decyclizing) - genetics | Ovarian Neoplasms - drug therapy | Isoenzymes - physiology | RNA, Small Interfering - pharmacology | Hydrogen Peroxide - pharmacology | Cisplatin - pharmacology | Esterases - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Cell Line, Tumor | Oxidative Stress - drug effects | Isoenzymes - biosynthesis | Antimitotic agents | Carcinoma | Antineoplastic agents | Cancer | Index Medicus
Journal Article
Journal Article
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2006, Volume 102, Issue 2, pp. 173 - 181
Journal Article
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2004, Volume 54, Issue 4, pp. 301 - 307
Journal Article
Cancer Research, ISSN 0008-5472, 02/1999, Volume 59, Issue 3, pp. 607 - 614
Journal Article
Journal Article