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PLOS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5
O-6-methylguanine-DNA methyltransferase (MGMT) is one of the major DNA repair protein that counteracts the alkalyting agent-induced DNA damage by replacing... 
LUNG-CANCER | MOLECULAR-DYNAMICS | HUMAN O-ALKYLGUANINE-DNA ALKYLTRANSFERASE | POLYMORPHISMS | MULTIDISCIPLINARY SCIENCES | AMINO-ACID SUBSTITUTIONS | RISK | KASHMIR | MUTATIONS | DNA-REPAIR | N-NITROSO COMPOUNDS
Journal Article
BIOESSAYS, ISSN 0265-9247, 03/2002, Volume 24, Issue 3, pp. 255 - 266
The DNA in human cells is continuously undergoing damage as consequences of both endogenous processes and exposure to exogenous agents. The resulting... 
RAT-LIVER DNA | METHYLATING AGENTS | GENE O-6-METHYLGUANINE-DNA METHYLTRANSFERASE | ALKYLATING-AGENTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | NITRO-N-NITROSOGUANIDINE | DNA-REPAIR GENES | HUMAN O-METHYLGUANINE-DNA METHYLTRANSFERASE | MISMATCH REPAIR | TUMOR-CELLS | O-ALKYLGUANINE-DNA ALKYLTRANSFERASE
Journal Article
CHEMBIOCHEM, ISSN 1439-4227, 07/2005, Volume 6, Issue 7, pp. 1263 - 1269
Fusion proteins of human O-6-alkylguanine-DNA alkyltransferose (AGT) can be specifically labeled with a wide variety of synthetic probes in mammalian cells;... 
SITE | CHEMISTRY, MEDICINAL | protein modifications | HUMAN O-ALKYLGUANINE-DNA ALKYLTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | alkyltransferases | LIVE CELLS | fluorescent probes | AGT | INACTIVATION | protein engineering | REPAIR | MOLECULES IN-VIVO | METHYLTRANSFERASE MGMT | BINDING | directed evolution | FUSION PROTEINS
Journal Article
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 10/2008, Volume 47, Issue 41, pp. 10892 - 10903
O 6-Alkylguanine-DNA alkyltransferase (AGT) plays an important role by protecting cells from alkylating agents. This reduces the frequency of carcinogenesis... 
DNA-BINDING | HUMAN O-ALKYLGUANINE-DNA ALKYLTRANSFERASE | HUMAN-TUMOR CELLS | CANCER-CHEMOTHERAPY | ALKYLATING-AGENTS | DIFFERENTIAL INACTIVATION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMATOPOIETIC STEM-CELLS | ESCHERICHIA-COLI | O-6-METHYLGUANINE-DNA METHYLTRANSFERASE
Journal Article
DNA Repair, ISSN 1568-7864, 2007, Volume 6, Issue 8, pp. 1071 - 1078
Journal Article
ChemBioChem, ISSN 1439-4227, 12/2017, Volume 18, Issue 23, pp. 2351 - 2357
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 12/2007, Volume 20, Issue 12, pp. 1966 - 1971
O 6-Alkylguanine-DNA alkyltransferase (AGT) repairs O 6-alkylguanine residues at different rates depending on the identity of the alkyl group as well as the... 
OLIGODEOXYNUCLEOTIDES | CHEMISTRY, MEDICINAL | HUMAN O-ALKYLGUANINE-DNA ALKYLTRANSFERASE | PROTEIN | OXIDATIVE DEMETHYLATION | O-6-METHYLGUANINE | ANALOGS | ESCHERICHIA-COLI | DNA ALKYLTRANSFERASE | CHEMISTRY, MULTIDISCIPLINARY | BASE | TOXICOLOGY | BINDING
Journal Article