Nature Reviews Neurology, ISSN 1759-4758, 12/2013, Volume 9, Issue 12, pp. 668 - 676
Rodent models of nerve injury have increased our understanding of peripheral nerve regeneration, but clinical applications have been scarce, partly because...
GROWTH-FACTOR RECEPTOR | NEURAL STEM-CELLS | FUNCTIONAL RECOVERY | SLOW WALLERIAN DEGENERATION | BETA-ACTIN SYNTHESIS | ELECTRICAL-STIMULATION | AXONAL REGENERATION | N-ACETYL-CYSTEINE | C57BL/OLA MICE | SCHWANN-CELLS | CLINICAL NEUROLOGY | Animals | Humans | Rats | Schwann Cells - physiology | Axons - physiology | Mice | Nerve Regeneration | Disease Models, Animal | Peripheral Nerve Injuries - therapy | Peripheral Nerves - physiopathology | Axons | Regeneration | Brain mapping | Physiological aspects | Nervous system | Models | Research
GROWTH-FACTOR RECEPTOR | NEURAL STEM-CELLS | FUNCTIONAL RECOVERY | SLOW WALLERIAN DEGENERATION | BETA-ACTIN SYNTHESIS | ELECTRICAL-STIMULATION | AXONAL REGENERATION | N-ACETYL-CYSTEINE | C57BL/OLA MICE | SCHWANN-CELLS | CLINICAL NEUROLOGY | Animals | Humans | Rats | Schwann Cells - physiology | Axons - physiology | Mice | Nerve Regeneration | Disease Models, Animal | Peripheral Nerve Injuries - therapy | Peripheral Nerves - physiopathology | Axons | Regeneration | Brain mapping | Physiological aspects | Nervous system | Models | Research
Journal Article
The Oncologist, ISSN 1083-7159, 02/2014, Volume 19, Issue 2, pp. 193 - 201
Learning Objectives Explain the characteristics and treatment of malignant peripheral nerve sheath tumors, both in relation to neurofibromatosis type I and...
Clinical trials | Molecular targeted therapy | Neurofibromatosis type 1 | Sarcoma | Malignant peripheral nerve sheath tumor | MAMMALIAN TARGET | NEUROFIBROMATOSIS TYPE-I | PHASE-II | SOFT-TISSUE | MPNST | GENE | ONCOLOGY | SARCOMA | NF1 | INHIBITOR | TYPE-1 | Animals | Nerve Sheath Neoplasms - therapy | Humans | Nerve Sheath Neoplasms - pathology | Nerve Sheath Neoplasms - diagnosis | Sarcomas
Clinical trials | Molecular targeted therapy | Neurofibromatosis type 1 | Sarcoma | Malignant peripheral nerve sheath tumor | MAMMALIAN TARGET | NEUROFIBROMATOSIS TYPE-I | PHASE-II | SOFT-TISSUE | MPNST | GENE | ONCOLOGY | SARCOMA | NF1 | INHIBITOR | TYPE-1 | Animals | Nerve Sheath Neoplasms - therapy | Humans | Nerve Sheath Neoplasms - pathology | Nerve Sheath Neoplasms - diagnosis | Sarcomas
Journal Article
Current Opinion in Biotechnology, ISSN 0958-1669, 2013, Volume 24, Issue 5, pp. 887 - 892
Graphical abstract
Internal Medicine | NEURITE EXTENSION | STEM-CELLS | CONDUCTING POLYMER | POLYPYRROLE | ELECTRICAL-STIMULATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NEUROTROPHIC FACTOR | REGENERATION | BIOCHEMICAL RESEARCH METHODS | SPINAL-CORD-INJURY | COLLAGEN SCAFFOLDS | FIBRIN MATRICES | Electric Stimulation | Biocompatible Materials - chemistry | Humans | Peripheral Nerve Injuries - pathology | Axons - drug effects | Axons - physiology | Biocompatible Materials - pharmacology | Peripheral Nerves - drug effects | Peripheral Nerves - pathology | Peripheral Nerve Injuries - therapy | Tissue Scaffolds | Animals | Peripheral Nerves - physiology | Nerve Regeneration - drug effects | Guided Tissue Regeneration | Tissue Engineering
Internal Medicine | NEURITE EXTENSION | STEM-CELLS | CONDUCTING POLYMER | POLYPYRROLE | ELECTRICAL-STIMULATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NEUROTROPHIC FACTOR | REGENERATION | BIOCHEMICAL RESEARCH METHODS | SPINAL-CORD-INJURY | COLLAGEN SCAFFOLDS | FIBRIN MATRICES | Electric Stimulation | Biocompatible Materials - chemistry | Humans | Peripheral Nerve Injuries - pathology | Axons - drug effects | Axons - physiology | Biocompatible Materials - pharmacology | Peripheral Nerves - drug effects | Peripheral Nerves - pathology | Peripheral Nerve Injuries - therapy | Tissue Scaffolds | Animals | Peripheral Nerves - physiology | Nerve Regeneration - drug effects | Guided Tissue Regeneration | Tissue Engineering
Journal Article
1995, Blue books of practical neurology, ISBN 0750617659, Volume 15, xii, 316
Book
The Journal of Bone & Joint Surgery, ISSN 0021-9355, 12/2013, Volume 95, Issue 23, pp. 2144 - 2151
➤ When possible, direct repair remains the current standard of care for the repair of peripheral nerve lacerations.➤ In large nerve gaps, in which direct...
SURGERY | POLYGLYCOLIC ACID | PROSPECTIVE CLINICAL-EVALUATION | REGENERATION | MOTOR | SHAFT FRACTURE | INJURY | FIBRIN GLUE | SCHWANN-CELLS | ORTHOPEDICS | RAT MODEL | CONDUITS | Autografts | Surgical Flaps | Time-to-Treatment | Humans | Nerve Regeneration - physiology | Treatment Outcome | Polyglycolic Acid - therapeutic use | Peripheral Nerves - surgery | Diagnostic Imaging - methods | Tissue Scaffolds | Peripheral Nerve Injuries - surgery | Peripheral Nerves - physiology | Peripheral Nerve Injuries - diagnosis | Collagen - therapeutic use | Neurosurgical Procedures - methods
SURGERY | POLYGLYCOLIC ACID | PROSPECTIVE CLINICAL-EVALUATION | REGENERATION | MOTOR | SHAFT FRACTURE | INJURY | FIBRIN GLUE | SCHWANN-CELLS | ORTHOPEDICS | RAT MODEL | CONDUITS | Autografts | Surgical Flaps | Time-to-Treatment | Humans | Nerve Regeneration - physiology | Treatment Outcome | Polyglycolic Acid - therapeutic use | Peripheral Nerves - surgery | Diagnostic Imaging - methods | Tissue Scaffolds | Peripheral Nerve Injuries - surgery | Peripheral Nerves - physiology | Peripheral Nerve Injuries - diagnosis | Collagen - therapeutic use | Neurosurgical Procedures - methods
Journal Article
Advanced Drug Delivery Reviews, ISSN 0169-409X, 03/2015, Volume 82-83, pp. 160 - 167
Peripheral nerve injuries represent a substantial clinical problem with insufficient or unsatisfactory treatment options. This review summarises all the events...
Neuronal survival | Muscle denervation | Reinnervation | Scaffold | Peripheral nerve regeneration | Stem cell | FUNCTIONAL RECOVERY | NEUROTROPHIC FACTOR | N-ACETYL-CYSTEINE | RAT SCIATIC-NERVE | MESENCHYMAL STEM-CELLS | I GENE-TRANSFER | HUMAN ADIPOSE-TISSUE | PHARMACOLOGY & PHARMACY | PRIMARY SENSORY NEURONS | GROWTH-FACTOR | SCHWANN-CELLS | Animals | Peripheral Nerve Injuries - physiopathology | Tissue Engineering - methods | Peripheral Nerve Injuries - surgery | Guided Tissue Regeneration - methods | Humans | Nerve Regeneration - physiology | Nerve Regeneration - drug effects | Tissue Engineering - trends | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology
Neuronal survival | Muscle denervation | Reinnervation | Scaffold | Peripheral nerve regeneration | Stem cell | FUNCTIONAL RECOVERY | NEUROTROPHIC FACTOR | N-ACETYL-CYSTEINE | RAT SCIATIC-NERVE | MESENCHYMAL STEM-CELLS | I GENE-TRANSFER | HUMAN ADIPOSE-TISSUE | PHARMACOLOGY & PHARMACY | PRIMARY SENSORY NEURONS | GROWTH-FACTOR | SCHWANN-CELLS | Animals | Peripheral Nerve Injuries - physiopathology | Tissue Engineering - methods | Peripheral Nerve Injuries - surgery | Guided Tissue Regeneration - methods | Humans | Nerve Regeneration - physiology | Nerve Regeneration - drug effects | Tissue Engineering - trends | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology
Journal Article
British Journal of Anaesthesia, ISSN 0007-0912, 12/2010, Volume 105, Issue suppl_1, pp. i97 - i107
Complications of peripheral nerve blocks are fortunately rare, but can be devastating for both the patient and the anaesthesiologist. This review will...
complications | regional anaesthesia | nerve, damage (postoperative), local anaesthesia | damage (postoperative) | INTRANEURAL INJECTION | POSTOPERATIVE ANALGESIA | LIPID EMULSION INFUSION | local anaesthesia | CONTINUOUS INTERSCALENE BLOCK | nerve | INDUCED CARDIAC-ARREST | BRACHIAL-PLEXUS BLOCK | ANESTHESIOLOGY | AMBULATORY SHOULDER SURGERY | STIMULATING CATHETERS | ANESTHETIC SYSTEMIC TOXICITY | REGIONAL-ANESTHESIA | Catheterization, Peripheral - instrumentation | Nerve Block - instrumentation | Peripheral Nerves - anatomy & histology | Humans | Ultrasonography, Interventional | Equipment Contamination | Nerve Block - methods | Nerve Block - adverse effects | Anesthetics, Local - adverse effects | Peripheral Nerves - diagnostic imaging | Needles | Catheterization, Peripheral - adverse effects | Equipment Failure | Peripheral Nerve Injuries
complications | regional anaesthesia | nerve, damage (postoperative), local anaesthesia | damage (postoperative) | INTRANEURAL INJECTION | POSTOPERATIVE ANALGESIA | LIPID EMULSION INFUSION | local anaesthesia | CONTINUOUS INTERSCALENE BLOCK | nerve | INDUCED CARDIAC-ARREST | BRACHIAL-PLEXUS BLOCK | ANESTHESIOLOGY | AMBULATORY SHOULDER SURGERY | STIMULATING CATHETERS | ANESTHETIC SYSTEMIC TOXICITY | REGIONAL-ANESTHESIA | Catheterization, Peripheral - instrumentation | Nerve Block - instrumentation | Peripheral Nerves - anatomy & histology | Humans | Ultrasonography, Interventional | Equipment Contamination | Nerve Block - methods | Nerve Block - adverse effects | Anesthetics, Local - adverse effects | Peripheral Nerves - diagnostic imaging | Needles | Catheterization, Peripheral - adverse effects | Equipment Failure | Peripheral Nerve Injuries
Journal Article
Clinical Neurophysiology, ISSN 1388-2457, 2008, Volume 119, Issue 9, pp. 1951 - 1965
Abstract Common etiologies of acute traumatic peripheral nerve injury (TPNI) include penetrating injury, crush, stretch, and ischemia. Management of TPNI...
Neurology | Peripheral nerve | Electrodiagnosis | Electromyography | Trauma | Injury | Surgery | trauma | FIBRILLATION POTENTIALS | TO-SIDE NEURORRHAPHY | peripheral nerve | GROWTH CONE GUIDANCE | WALLERIAN DEGENERATION | AXONAL REGENERATION | ACCELERATES FUNCTIONAL RECOVERY | BRACHIAL-PLEXUS PALSY | NEUROSCIENCES | CLINICAL NEUROLOGY | electromyography surgery | SCIATIC-NERVE | electrodiagnosis | ELECTRICAL-STIMULATION | injury | SCHWANN-CELLS | Action Potentials - physiology | Trauma, Nervous System - pathology | Animals | Humans | Muscle, Skeletal - physiopathology | Evaluation Studies as Topic | Trauma, Nervous System - therapy | Peripheral Nerve Injuries
Neurology | Peripheral nerve | Electrodiagnosis | Electromyography | Trauma | Injury | Surgery | trauma | FIBRILLATION POTENTIALS | TO-SIDE NEURORRHAPHY | peripheral nerve | GROWTH CONE GUIDANCE | WALLERIAN DEGENERATION | AXONAL REGENERATION | ACCELERATES FUNCTIONAL RECOVERY | BRACHIAL-PLEXUS PALSY | NEUROSCIENCES | CLINICAL NEUROLOGY | electromyography surgery | SCIATIC-NERVE | electrodiagnosis | ELECTRICAL-STIMULATION | injury | SCHWANN-CELLS | Action Potentials - physiology | Trauma, Nervous System - pathology | Animals | Humans | Muscle, Skeletal - physiopathology | Evaluation Studies as Topic | Trauma, Nervous System - therapy | Peripheral Nerve Injuries
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 24, pp. 6143 - 6156
Abstract Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to autologous nerve grafts, the gold standard for peripheral nerve...
Advanced Basic Science | Dentistry | Neural templates | Physicochemical and biological cues | Peripheral nerve regeneration | Tissue engineered nerve graft (TENG) | Neural tissue engineering | MATERIALS SCIENCE, BIOMATERIALS | ELECTRICAL-STIMULATION PROMOTES | LONG NONCODING RNAS | ENGINEERING, BIOMEDICAL | DORSAL-ROOT GANGLIA | RAT SCIATIC-NERVE | MESENCHYMAL STEM-CELLS | OLFACTORY ENSHEATHING CELLS | FUNCTIONAL MOTOR RECOVERY | SKIN-DERIVED PRECURSORS | SCHWANN-CELLS | ENDOTHELIAL GROWTH-FACTOR | RNA Interference - drug effects | Animals | Tissue Engineering - methods | Peripheral Nerves - physiology | Humans | Nerve Regeneration - physiology | Nerve Regeneration - drug effects | Biocompatible Materials - pharmacology | Peripheral Nerves - drug effects | Tissue Scaffolds - chemistry | Antioxidants | Biological products | Peptides | Tissue engineering | Analysis
Advanced Basic Science | Dentistry | Neural templates | Physicochemical and biological cues | Peripheral nerve regeneration | Tissue engineered nerve graft (TENG) | Neural tissue engineering | MATERIALS SCIENCE, BIOMATERIALS | ELECTRICAL-STIMULATION PROMOTES | LONG NONCODING RNAS | ENGINEERING, BIOMEDICAL | DORSAL-ROOT GANGLIA | RAT SCIATIC-NERVE | MESENCHYMAL STEM-CELLS | OLFACTORY ENSHEATHING CELLS | FUNCTIONAL MOTOR RECOVERY | SKIN-DERIVED PRECURSORS | SCHWANN-CELLS | ENDOTHELIAL GROWTH-FACTOR | RNA Interference - drug effects | Animals | Tissue Engineering - methods | Peripheral Nerves - physiology | Humans | Nerve Regeneration - physiology | Nerve Regeneration - drug effects | Biocompatible Materials - pharmacology | Peripheral Nerves - drug effects | Tissue Scaffolds - chemistry | Antioxidants | Biological products | Peptides | Tissue engineering | Analysis
Journal Article