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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 03/2010, Volume 107, Issue 12, pp. 5587 - 5592
...), a pore-forming toxin that targets polymorphonuclear leukocytes (PMNs). PVL is thought to play a key role in the pathogenesis of necrotizing pneumonia, but data from rodent infection models are inconclusive... 
Acute lung injury | Pneumonia | Staphylococcal pneumonia | Lungs | Neutrophils | Sprains and strains | Infections | Toxins | Leukocidins | Staphylococcus aureus | USA300 | Virulence | MRSA | Rabbit infection model | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Bacterial Toxins - toxicity | Pneumonia, Staphylococcal - pathology | Pneumonia, Staphylococcal - microbiology | Genetic Complementation Test | Methicillin-Resistant Staphylococcus aureus - pathogenicity | Pneumonia, Staphylococcal - etiology | Virulence - genetics | Gene Deletion | Leukocidins - toxicity | Bacterial Toxins - genetics | Methicillin-Resistant Staphylococcus aureus - genetics | Disease Models, Animal | Neutrophils - pathology | Leukocidins - genetics | Genes, Bacterial | Rabbits | Neutrophils - drug effects | Neutrophils - physiology | Acute Lung Injury - pathology | Acute Lung Injury - microbiology | Animals | Exotoxins - genetics | Exotoxins - toxicity | In Vitro Techniques | Acute Lung Injury - etiology | Physiological aspects | Causes of | Development and progression | Leukocytes | Staphylococcus aureus infections | Index Medicus | Cytolysis | Edema | Epidemics | Animal models | Lung | Cytotoxicity | Data processing | Inflammation | Drug resistance | Hemorrhage | leukocidin | Necrosis | Infection | Hemoptysis | Acquired immune deficiency syndrome | Granules | Leukocytes (polymorphonuclear) | Alveoli | pandemics | Injuries | Public health | Biological Sciences | virulence | pneumonia | rabbit infection model
Journal Article
PloS one, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, pp. e101848 - e101848
Journal Article
Lung, ISSN 0341-2040, 2/2018, Volume 196, Issue 1, pp. 27 - 31
Journal Article
Journal of thrombosis and haemostasis, ISSN 1538-7933, 01/2016, Volume 14, Issue 1, pp. 191 - 204
...) interactions and prevents the prothrombotic functions of polymorphonuclear leukocytes (PMNs) and monocytes (MNs). Methods Using well-characterized in vitro models, we analysed the effects of RNO... 
leukocytes | blood platelets | thrombosis | signal transduction | pharmacology | Signal transduction | Pharmacology | Leukocytes | Blood platelets | Thrombosis | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Neutrophils - cytology | Phosphorylation | Monocytes - cytology | P-Selectin - metabolism | Cardiovascular Diseases - prevention & control | Humans | Fibrinogen - chemistry | Risk | Phosphatidylinositol 3-Kinases - metabolism | Benzamides - pharmacology | Thrombosis - blood | Blood Platelets - drug effects | Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism | Cyclopropanes - pharmacology | Neutrophils - drug effects | P-Selectin - genetics | Phosphodiesterase 4 Inhibitors - pharmacology | Platelet Adhesiveness - drug effects | Monocytes - drug effects | Microscopy, Confocal | Animals | Macrophage-1 Antigen - genetics | Aminopyridines - pharmacology | Leukocytes - drug effects | Extracellular Traps | Mice | Thromboplastin - metabolism | Pulmonary Disease, Chronic Obstructive - drug therapy | Prevention | Fibrin | Lung diseases, Obstructive | Comorbidity | Analysis | Fibrinogen | Cellular signal transduction | Chronic obstructive pulmonary disease | Granulocytes | Kinases | Index Medicus
Journal Article
Journal of biomedical materials research. Part A, ISSN 1549-3296, 12/2015, Volume 103, Issue 12, pp. 3772 - 3780
Journal Article