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Cancer Science, ISSN 1347-9032, 12/2019, Volume 110, Issue 12, pp. 3773 - 3787
Vascular endothelial growth factor receptor 2 (VEGFR2) is highly expressed in tumor‐associated endothelial cells, where it modulates tumor‐promoting... 
VEGFR2 | targeted cancer therapy | phage display | human antibody | angiogenesis
Journal Article
Biomolecules, ISSN 2218-273X, 11/2019, Volume 9, Issue 11, p. 681
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. Cetuximab, a human/mouse chimeric monoclonal antibody, is effective in a... 
grp94 | cetuximab resistance | colorectal cancer | human antibody
Journal Article
Hepatology (Baltimore, Md.), ISSN 0270-9139, 12/2016, Volume 64, Issue 6, pp. 1922 - 1933
Direct acting antivirals (DAAs) have led to a high cure rate in treated patients with chronic hepatitis C virus (HCV) infection but this still leaves a large... 
hepatitis C virus | resistant-associated variants and protective immunity | human antibody
Journal Article
Science Translational Medicine, ISSN 1946-6234, 04/2018, Volume 10, Issue 438
Today's most transformative medicines exist because of fundamental discoveries that were made without regard to practical outcome and with their relevance to... 
CHRONIC MYELOGENOUS LEUKEMIA | DEPENDENT DNA-POLYMERASE | MEDICINE, RESEARCH & EXPERIMENTAL | CHROMOSOME | IN-VITRO | HUMAN-ANTIBODY | VIRUS | BCR/ABL | VIRIONS | MICE | INDUCTION | CELL BIOLOGY
Journal Article
JOURNAL OF VIROLOGY, ISSN 0022-538X, 05/2019, Volume 93, Issue 9
Parvovirus B19, one of the most common human pathogens, is a small DNA virus that belongs to the Parvoviridae. As a result of previous infections, antibodies... 
PERSISTENCE | RECEPTOR | B19 parvovirus | MICROSCOPY | ADENOASSOCIATED VIRUS-2 | VIROLOGY | INFECTION | CELLULAR CORECEPTOR | epitope | MONOCLONAL-ANTIBODIES | cryo-EM | human antibody | CRYO-EM STRUCTURE | APLASTIC CRISIS | NEUTRALIZATION
Journal Article
Structure, ISSN 0969-2126, 02/2019, Volume 27, Issue 2, pp. 253 - 267.e8
Dengue virus (DENV) particles are released from cells in different maturation states. Fully immature DENV (immDENV) is generally non-infectious, but can become... 
enhancement of infection | maturation | immature dengue virus | cryo-EM | human antibody | dengue virus | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FORCE-FIELD | ENVELOPE PROTEIN | ELECTROSTATICS | MATURATION | EXCHANGE | MOLECULAR-DYNAMICS SIMULATION | SOFTWARE | FEATURES | CELL BIOLOGY
Journal Article
Journal of Medical Microbiology, ISSN 0022-2615, 03/2018, Volume 67, Issue 3, pp. 423 - 431
Purpose. To explore an epitope-based vaccine against Staphylococcus aureus, we screened the epitopes in the N2N3 subdomain of fibronectin-binding protein A... 
Fibronectin binding protein A | Monoclonal antibody | Epitope | N2N3 | Staphylococcus aureus | HUMAN-ANTIBODY RESPONSE | PHAGE DISPLAY | MICROBIOLOGY | VIRULENCE | MSCRAMM | DOMAIN SPECIFICITY | MASTITIS | ELASTIN | INFECTION | epitope | monoclonal antibody | fibronectin binding protein A | FIBRINOGEN | ANTIGEN | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2015, Volume 194, Issue 1, pp. 252 - 261
High-throughput sequencing allows detailed study of the BCR repertoire postimmunization, but it remains unclear to what extent the de novo identification of... 
REGION GENE USAGE | CAPSULAR POLYSACCHARIDE | INFLUENZAE TYPE-B | HUMAN-ANTIBODY RESPONSE | NEUTRALIZING ANTIBODIES | IMMUNOGLOBULIN REPERTOIRE | HIGH-AFFINITY | SOMATIC MUTATION | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | SUBCLASS ANTIBODIES
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2013, Volume 169, Issue 1, pp. 51 - 68
Background and Purpose AMG 181 is a human anti‐α4β7 antibody currently in phase 1 and 2 trials in subjects with inflammatory bowel diseases. AMG 181... 
α4β7 integrin | inflammatory bowel diseases | AMG 181 | gut‐homing | anti‐α4β7 | cell trafficking | Crohn's disease | ulcerative colitis | T cells | human antibody | α | β | gut-homing | integrin | anti-α | Research Papers | anti-α4β7
Journal Article
Cancer Research and Treatment, ISSN 1598-2998, 07/2018, Volume 50, Issue 3, pp. 1009 - 1022
Purpose Glioblastoma (GBM) is classified as one of the most aggressive and lethal brain tumor. Great strides have been made in understanding the genomic and... 
Fully human antibody | Semaphorin-3A | Glioblastoma | Neutralization | TARGET | CELLS | ANGIOGENESIS | ONCOLOGY | VASCULAR-PERMEABILITY | SEMAPHORIN 3A | Original
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 04/2019, Volume 20, Issue 8, p. 1967
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces cancer cell death with minimal damage to normal cells; however, some cancer cells... 
Mitochondria | TRAIL | P38 | Fab | Cancer cells | DR4 | Agonistic human antibody | TRAIL-resistance | TRAIL receptor 1 | PROTEIN | MECHANISM | INDUCED APOPTOSIS | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | cancer cells | agonistic human antibody | INDUCTION | AUTOPHAGY | CANCER | CHEMISTRY, MULTIDISCIPLINARY | MOLECULAR TARGETS | INHIBITION | p38 | RESISTANCE | TUMORICIDAL ACTIVITY
Journal Article
Theranostics, ISSN 1838-7640, 2018, Volume 8, Issue 13, pp. 3629 - 3642
Zika virus (ZIKV) has been identified as a cause of adverse outcomes of pregnancy, including microcephaly and other congenital diseases. Most people infected... 
Urine | Immunoassay | Serum | Zika virus | Peptide aptamer | MEDICINE, RESEARCH & EXPERIMENTAL | DIAGNOSIS | HUMAN-ANTIBODY RESPONSES | urine | STABILIZATION | B-CELL EPITOPES | HORSERADISH-PEROXIDASE | immunoassay | PREDICTION | peptide aptamer | DENGUE | INFECTION | LIGAND | serum | SELECTION
Journal Article