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Clinical Cancer Research, ISSN 1078-0432, 01/2019, Volume 25, Issue 2, pp. 629 - 640
Purpose: The molecular events that determine intestinal cell differentiation are poorly understood and it is unclear whether it is primarily a passive event or... 
HUMAN COLON | TARGET | ACTIVATION | GENE | ONCOLOGY | ADENOCARCINOMA | RESISTANCE
Journal Article
Clinical Biomechanics, ISSN 0268-0033, 05/2019, Volume 65, pp. 34 - 40
Data from biomechanical tissue sample studies of the human digestive tract are highly variable. The aim of this study was to investigate 4 factors which could... 
Biomechanics | Colonic mechanical response | Human colon | Dynamic solicitation
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 06/2005, Volume 23, Issue 16, pp. 3697 - 3705
Purpose Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, increases survival when combined with irinotecan-based chemotherapy in... 
SOLID TUMORS | ANGIOGENESIS | ONCOLOGY | HUMAN COLON-CANCER | IN-VIVO | IRINOTECAN | MONOCLONAL-ANTIBODY | LIVER METASTASIS | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | PLUS FLUOROURACIL
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 09/2009, Volume 11, Issue 9, pp. 1135 - U208
The finite proliferative potential of normal human cells leads to replicative cellular senescence, which is a critical barrier to tumour progression in... 
APOPTOSIS | CELLS | DOWNSTREAM TARGET | MIR-34A | HUMAN-COLON | GENE | DNA-DAMAGE | ONCOGENE-INDUCED SENESCENCE | EXPRESSION | CANCER | CELL BIOLOGY
Journal Article
CARCINOGENESIS, ISSN 0143-3334, 03/2009, Volume 30, Issue 3, pp. 377 - 386
It is widely accepted that alterations to cyclooxygenase-2 (COX-2) expression and the abundance of its enzymatic product prostaglandin E-2 (PGE(2)) have key... 
SIZE-DEPENDENT INCREASE | ONCOLOGY | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | EPIDERMAL-GROWTH-FACTOR | HUMAN COLON-CANCER | CYCLOOXYGENASE-2 EXPRESSION | FAMILIAL ADENOMATOUS POLYPOSIS | NF-KAPPA-B | INTESTINAL EPITHELIAL-CELLS | PROSTAGLANDIN E-2 | HUMAN COLORECTAL-CANCER
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 04/2018, Volume 46, Issue 6, pp. 3009 - 3018
Abstract We systematically studied the association between somatic copy number aberration (SCNA), DNA methylation and gene expression using -omic data from The... 
HUMAN COLON | SITES | GENOMICS | CANCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | BREAST | Genomics
Journal Article
Diabetes, ISSN 0012-1797, 02/2012, Volume 61, Issue 2, pp. 364 - 371
Interest in how the gut microbiome can influence the metabolic state of the host has recently heightened. One postulated link is bacterial fermentation of... 
HUMAN COLON | PROPIONATE | GLP-1 | RAT | RESISTANT STARCH | ENDOCRINOLOGY & METABOLISM | GPR41 | FUNCTIONAL-CHARACTERIZATION | ACETATE | IDENTIFICATION | Physiological aspects | Cell receptors | Research | Peptides | Fatty acids | Index Medicus | Abridged Index Medicus | Signal Transduction
Journal Article
Cancer Research, ISSN 0008-5472, 02/2019, Volume 79, Issue 3, pp. 495 - 504
Many normal tissues undergo age-related drift in DNA methylation, providing a quantitative measure of tissue age. Here, we identify and validate 781 CpG... 
HUMAN COLON | METHYLATION | ONCOLOGY | LANDSCAPE | PATHWAY | PROLIFERATION | MUTATIONS | REVEAL | CANCER | PROGRESSION | LESIONS
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 2014, Volume 59, Issue 6, pp. 1169 - 1179
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 2019, Volume 25, Issue 9, pp. 2821 - 2834
Purpose: Genomic and transcriptomic alterations during metastasis are considered to affect clinical outcome of colorectal cancers, but detailed clinical... 
HUMAN COLON | EVOLUTION | INSTABILITY | MODELS | ONCOLOGY | INTRATUMOR HETEROGENEITY | RESISTANCE | MUTATIONS | XENOGRAFTS
Journal Article
MOLECULAR & CELLULAR PROTEOMICS, ISSN 1535-9476, 08/2019, Volume 18, pp. S114 - S125
Proteogenomic studies of cancer samples have shown that copy-number variation can be attenuated at the protein level for a large fraction of the proteome,... 
HUMAN COLON | RNA | PROTEOGENOMIC CHARACTERIZATION | STABILITY | GENE ORDER | BIOCHEMICAL RESEARCH METHODS | R PACKAGE | CANCER | EXPRESSION
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2014, Volume 723, Issue 1, pp. 62 - 66
The effect of two novel -adrenoceptor ( -AR) agonists SP-1f and SP-1h on human colon circular smooth muscle contractility and -AR mRNA expression have been... 
AR | Agonist | Human colon motility | Adrenoceptor
Journal Article
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, ISSN 1072-7515, 07/2014, Volume 219, Issue 1, pp. 132 - 141
BACKGROUND: Our laboratory has previously developed fluorescence-guided surgery of pancreatic and other cancers in orthotopic mouse models. Laparoscopic... 
SURVIVAL | SURGERY | NUDE-MICE | IMAGING-SYSTEM | CEA ANTIBODY | HUMAN COLON-CANCER | TUMOR | PATIENT | FUTURE | COMPLETE RESECTION
Journal Article
Analytical Chemistry, ISSN 0003-2700, 07/2018, Volume 90, Issue 14, pp. 8396 - 8403
Comprehensive metabolomic data can be achieved using multiple orthogonal separation and mass spectrometry (MS) analytical techniques. However, drawing... 
HUMAN COLON | CHEMISTRY, ANALYTICAL | METABOLITES | MASS-SPECTROMETRY DATA | OMICS DATA | COVERAGE | XCMS | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2015, Volume 47, Issue 4, pp. 320 - 329
Journal Article
Anaerobe, ISSN 1075-9964, 08/2013, Volume 22, pp. 25 - 30
Clostridium difficile is a leading cause of hospital-acquired diarrhoea and represents a major challenge for healthcare providers. Due to the decreasing... 
Toxin | Bacteriophage therapy | Clostridium difficile | Lysogeny | Human colon model
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 04/2019, Volume 17, Issue 4, pp. 882 - 894
Serine threonine kinase 17A (STK17A) is a ubiquitously expressed kinase originally identified as a regulator of apoptosis; however, whether it functionally... 
HUMAN COLON | APOPTOSIS | ACTIVATION | TGF-BETA | GENE | ONCOLOGY | STATISTICS | PROTEIN-KINASE | ADENOCARCINOMA | DEATH | BINDING | CELL BIOLOGY
Journal Article
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