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SCIENTIFIC REPORTS, ISSN 2045-2322, 02/2019, Volume 9, Issue 1, pp. 3177 - 13
Human aldose reductase (hAR, AKR1B1) has been explored as drug target since the 1980s for its implication in diabetic complications. An activated form of hAR... 
RADIOLYSIS | IN-VITRO | ACTIVATION | SMALL-ANGLE SCATTERING | SPECIFICITY | MECHANISM | MULTIDISCIPLINARY SCIENCES | RADIATION-DAMAGE | MACROMOLECULAR CRYSTALLOGRAPHY | HUMAN-ERYTHROCYTE | MOLECULES | Oxidative stress | Alanine | Enzymatic activity | Diabetes mellitus | Serine | Clinical trials | Aldehyde reductase | Diabetes | Reductase
Journal Article
Biochimie, ISSN 0300-9084, 05/2019, Volume 160, pp. 100 - 112
Acetylcholinesterase (AChE) is the primary target of organophosphorus pesticides (OPs). Ellman's method using Acetylthiocholine (ATCh) is the standard approach... 
Fluorescence | Oxime combination | Organophosphorus pesticides | 1-Naphthyl acetate | Acetylcholinesterase | BUTYRYLCHOLINESTERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | IN-VITRO | OXIMES | CHLORPYRIFOS | REACTIVATION | MOLECULAR PROBE | PRALIDOXIME | HUMAN ERYTHROCYTE ACETYLCHOLINESTERASE | INHIBITED HUMAN ACETYLCHOLINESTERASE | Pesticides | Index Medicus
Journal Article
New Journal of Chemistry, ISSN 1144-0546, 2017, Volume 41, Issue 10, pp. 4048 - 4057
In this work, the interaction between a commonly used multifunctional fluorescent drug chlorpromazine (CPZ) and model cell membranes (liposomes, giant... 
TIME-RESOLVED FLUORESCENCE | LIPID-BILAYERS | RESTRICTED INTRAMOLECULAR ROTATION | ACYL-CHAIN | DRUG-INTERACTIONS | HUMAN-ERYTHROCYTE MEMBRANE | RED-BLOOD-CELLS | VIBRATIONAL SPECTROSCOPY | PROTEIN-BINDING | CHEMISTRY, MULTIDISCIPLINARY | BOVINE SERUM-ALBUMIN
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 10/2018, Volume 655, pp. 67 - 74
Carbamates are esters of substituted carbamic acids that react with acetylcholinesterase (AChE) by initially transferring the carbamoyl group to a serine... 
Decarbamoylation | Acetylcholinesterase | Alzheimer's disease | CATALYSIS | TORPEDO-CALIFORNICA | ALZHEIMERS-DISEASE | REACTION-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRYSTAL-STRUCTURES | THIOFLAVIN T | PERIPHERAL SITE | INHIBITION | BIOPHYSICS | HUMAN-ERYTHROCYTE ACETYLCHOLINESTERASE | ACID ESTERS | Alzheimer’s disease
Journal Article
The Analyst, ISSN 0003-2654, 02/2018, Volume 143, Issue 5, pp. 1087 - 1093
Phospholipids are critical structural components of the membrane of human erythrocytes and their asymmetric transbilayer distribution is essential for normal... 
Microscopy - methods | Cell Shape | Humans | Phospholipids - analysis | Ions | Erythrocytes - chemistry | Phosphatidylserines - analysis | Phosphatidylcholines - analysis
Journal Article