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PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23293
HIV proteins target host hub proteins for transient binding interactions. The presence of viral proteins in the infected cell results in out-competition of... 
REPLICATION | PHOSPHORYLATION | TAT | MULTIDISCIPLINARY SCIENCES | KINASE | IMMUNODEFICIENCY-VIRUS TYPE-1 | SH3 DOMAINS | SHORT LINEAR MOTIFS | BINDING | VIRAL-INFECTION | NEF | rev Gene Products, Human Immunodeficiency Virus - chemistry | Humans | env Gene Products, Human Immunodeficiency Virus - metabolism | rev Gene Products, Human Immunodeficiency Virus - metabolism | nef Gene Products, Human Immunodeficiency Virus - chemistry | tat Gene Products, Human Immunodeficiency Virus - chemistry | CREB-Binding Protein - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | env Gene Products, Human Immunodeficiency Virus - genetics | Human Immunodeficiency Virus Proteins - chemistry | Databases, Protein | nef Gene Products, Human Immunodeficiency Virus - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | env Gene Products, Human Immunodeficiency Virus - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Calmodulin - metabolism | Protein Structure, Secondary | tat Gene Products, Human Immunodeficiency Virus - genetics | Models, Molecular | gag Gene Products, Human Immunodeficiency Virus - chemistry | Binding Sites - genetics | Human Immunodeficiency Virus Proteins - metabolism | Proteins - genetics | Protein Interaction Mapping - methods | Proteins - metabolism | nef Gene Products, Human Immunodeficiency Virus - genetics | Hydrophobic and Hydrophilic Interactions | Protein Binding | Human Immunodeficiency Virus Proteins - genetics | rev Gene Products, Human Immunodeficiency Virus - genetics | Amino Acid Motifs - genetics | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Casein Kinase II - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | tat Gene Products, Human Immunodeficiency Virus - metabolism | Physiological aspects | Viral proteins | HIV (Viruses) | Genomics | Protein binding | Phenotypes | Phosphorylation | Hot spots | Crosstalk | Amino acid sequence | Viruses | Genomes | Kinases | Proteins | Conserved sequence | Algorithms | Human immunodeficiency virus--HIV | Computer applications | Mutation | Proteomes | Localization | Bioinformatics | Binding sites | HIV | Human immunodeficiency virus
Journal Article
Retrovirology, ISSN 1742-4690, 04/2010, Volume 7, Issue 1, pp. 34 - 34
The human immunodeficiency virus-1 (HIV-1) is a member of the lentivirus genus. The virus does not rely exclusively on the host cell machinery, but also on... 
OXIDE SYNTHASE EXPRESSION | TUMOR-NECROSIS-FACTOR | T-CELL APOPTOSIS | VIROLOGY | AIDS-DEMENTIA-COMPLEX | ENVELOPE GLYCOPROTEIN GP120 | CHEMOKINE RECEPTOR CXCR4 | PERIPHERAL-BLOOD MONOCYTES | HUMAN-IMMUNODEFICIENCY-VIRUS | NF-KAPPA-B | TYPE-1 TAT PROTEIN | HIV-1 - pathogenicity | Signal Transduction | Virulence Factors - physiology | HIV Infections - virology | Humans | nef Gene Products, Human Immunodeficiency Virus - physiology | vpr Gene Products, Human Immunodeficiency Virus - physiology | vpr Gene Products, Human Immunodeficiency Virus - immunology | Virulence Factors - immunology | Macrophage Activation | HIV Envelope Protein gp120 - immunology | HIV Infections - immunology | HIV-1 - immunology | tat Gene Products, Human Immunodeficiency Virus - physiology | nef Gene Products, Human Immunodeficiency Virus - immunology | HIV Envelope Protein gp120 - physiology | tat Gene Products, Human Immunodeficiency Virus - immunology | Macrophages - immunology | Viral proteins | Cellular signal transduction | Genetic aspects | Research | Genetic transcription | Health aspects | HIV infection | Risk factors | HIV Infections | HIV-1 | tat Gene Products, Human Immunodeficiency Virus | vpr Gene Products, Human Immunodeficiency Virus | HIV Envelope Protein gp120 | Macrophages | Virulence Factors | Life Sciences | Human health and pathology | Infectious diseases | nef Gene Products, Human Immunodeficiency Virus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e21225
Background: The safety and immunogenicity of a vaccine regimen consisting of a 6-plasmid HIV-1 DNA prime (envA, envB, envC, gagB, polB, nefB) boosted by a... 
RESPONSES | IMMUNITY | ASSAY | SAFETY | MULTIDISCIPLINARY SCIENCES | ANTIBODY | IMMUNOGENICITY EVALUATION | CANDIDATE | INFECTION | STEP | MEMORY T-CELLS | env Gene Products, Human Immunodeficiency Virus - immunology | Immunization, Secondary - adverse effects | Immunoglobulin G - blood | Human Immunodeficiency Virus Proteins - immunology | Humans | Middle Aged | AIDS Vaccines - immunology | Vaccines, DNA - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Male | Antibodies, Viral - blood | Vaccines, DNA - administration & dosage | Young Adult | env Gene Products, Human Immunodeficiency Virus - genetics | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Adenoviridae - genetics | Adult | Female | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Immunization - adverse effects | Enzyme-Linked Immunosorbent Assay | Immunization - methods | Anemia - chemically induced | Immunization, Secondary - methods | HIV-1 - genetics | HIV-1 - immunology | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - immunology | Adolescent | Antibodies, Viral - immunology | Human Immunodeficiency Virus Proteins - genetics | T-Lymphocytes - immunology | AIDS Vaccines - administration & dosage | gag Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - blood | Cohort Studies | Oligomers | AIDS vaccines | Adenoviruses | Immunotherapy | DNA | Clinical trials | Product development | Interferon | Biological response modifiers | T cells | HIV (Viruses) | Antigenic determinants | Health care | CD8 antigen | Antibodies | Lymphocytes T | Infections | Vaccines | Epidemiology | Randomization | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Inserts | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Binding | Medical research | Immunoglobulins | Cytokines | Epitopes | Immune response (humoral) | CD4 antigen | Disease prevention | Hospitals | Infectious diseases | Immunogenicity | γ-Interferon | Adults | Cancer | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article
Journal of Virology, ISSN 0022-538X, 03/2014, Volume 88, Issue 5, pp. 2633 - 2644
Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
HTLV-III | VIROLOGY | GP120 INNER DOMAIN | TRANSMEMBRANE GLYCOPROTEIN | EFFECTOR FUNCTION | IMMUNODEFICIENCY-VIRUS TYPE-1 | VPU PROTEIN | CONFORMATIONAL TRANSITIONS | VACCINE EFFICACY TRIAL | AIDS PATIENTS | DISEASE PROGRESSION | env Gene Products, Human Immunodeficiency Virus - immunology | Human Immunodeficiency Virus Proteins - immunology | Humans | Protein Multimerization | Antibody-Dependent Cell Cytotoxicity - immunology | env Gene Products, Human Immunodeficiency Virus - metabolism | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV Antibodies - immunology | nef Gene Products, Human Immunodeficiency Virus - metabolism | Protein Interaction Domains and Motifs | Epitopes, T-Lymphocyte - immunology | CD4-Positive T-Lymphocytes - virology | env Gene Products, Human Immunodeficiency Virus - chemistry | HIV Antibodies - metabolism | CD4 Antigens - immunology | Cell Line | Viral Regulatory and Accessory Proteins - immunology | Models, Molecular | Protein Binding - immunology | Viral Regulatory and Accessory Proteins - metabolism | Human Immunodeficiency Virus Proteins - metabolism | HIV-1 - immunology | CD4 Antigens - chemistry | nef Gene Products, Human Immunodeficiency Virus - immunology | Protein Conformation | Epitopes, T-Lymphocyte - metabolism | CD4 Antigens - metabolism | HIV Infections - metabolism | Pathogenesis and Immunity
Journal Article
Journal of virology, ISSN 1098-5514, 2018, Volume 93, Issue 1
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 1371 - 16
HIV-1 causes chronic inflammation and AIDS in humans, whereas related simian immunodeficiency viruses (SIVs) replicate efficiently in their natural hosts... 
SIMIAN-IMMUNODEFICIENCY-VIRUS | MULTIDISCIPLINARY SCIENCES | INFECTED SOOTY MANGABEYS | T-CELL-ACTIVATION | IN-VIVO | AFRICAN-GREEN MONKEYS | CD4 DOWN-REGULATION | HIV-1 VPU INTERFERENCE | NF-KAPPA-B | SIV INFECTION | LYMPHOCYTE-ACTIVATION | Bone Marrow Stromal Antigen 2 - genetics | HIV-1 - pathogenicity | Human Immunodeficiency Virus Proteins - immunology | Humans | Virulence | NF-kappa B - immunology | Cercopithecus aethiops | Simian Immunodeficiency Virus - growth & development | Viral Load | CD3 Complex - genetics | HIV-1 - growth & development | Female | Transcription, Genetic | Bone Marrow Stromal Antigen 2 - immunology | Amino Acid Sequence | Simian Immunodeficiency Virus - pathogenicity | Signal Transduction | Lentiviruses, Primate - growth & development | Lymphocyte Activation | Viral Regulatory and Accessory Proteins - immunology | Viral Regulatory and Accessory Proteins - genetics | Gene Expression Regulation | Host Specificity | Sequence Alignment | Animals | NF-kappa B - genetics | Virus Replication | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | CD3 Complex - immunology | Human Immunodeficiency Virus Proteins - genetics | Lentiviruses, Primate - pathogenicity | Pathogens | NF-κB protein | Viremia | Immunodeficiency | Vpu protein | Viruses | Activation | Monkeys | Lymphocytes T | CD3 antigen | Pathogenicity | Cell activation | Nef protein | Acquired immune deficiency syndrome--AIDS | Virulence factors | Transcription activation | Human immunodeficiency virus--HIV | HIV-1 | Viral Regulatory and Accessory Proteins | Life Sciences | NF-kappa B | Immunology | CD3 Complex | Human Immunodeficiency Virus Proteins | Animal biology | Virology | Human health and pathology | Microbiology and Parasitology | Infectious diseases | Lentiviruses, Primate | Bone Marrow Stromal Antigen 2 | Simian Immunodeficiency Virus | nef Gene Products, Human Immunodeficiency Virus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2012, Volume 7, Issue 4, p. e34723
HIV-1 candidate vaccines expressing an artificial polyprotein comprising Gag, Pol and Nef (GPN) and a secreted envelope protein (Env) were shown in recent... 
AIDS RESEARCH | IMMUNIZATION | T-CELL RESPONSES | VIRUS | PHASE-I TRIAL | IMMUNE-RESPONSES | BIOLOGY | ENVELOPE PROTEIN | INFECTION | NYVAC-C | EXPRESSION | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | Vaccines, DNA - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Vaccines, Synthetic - immunology | Vaccines, DNA - administration & dosage | Clinical Trials, Phase III as Topic | env Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - biosynthesis | HEK293 Cells | Female | pol Gene Products, Human Immunodeficiency Virus - genetics | Gene Products, gag - immunology | Gene Products, gag - genetics | Vaccines, Synthetic - genetics | nef Gene Products, Human Immunodeficiency Virus - biosynthesis | HIV-1 - genetics | Gene Products, gag - biosynthesis | HIV-1 - immunology | Animals | env Gene Products, Human Immunodeficiency Virus - biosynthesis | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | Vaccines, Virus-Like Particle - immunology | Mice | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | AIDS vaccines | Viral proteins | Vaccination | DNA | Amino acids | T cells | HIV (Viruses) | Antigenic determinants | Competition | CD8 antigen | Clinical trials | Viruses | Lymphocytes T | DNA vaccines | Histocompatibility antigen H-2 | Vaccines | Virus-like particles | Proteins | Clonal deletion | Gag protein | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Combined vaccines | Deoxyribonucleic acid--DNA | Medical research | Cytomegalovirus | Envelope protein | Gene expression | Nef protein | Immunogenicity | γ-Interferon | Budding | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article