X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (673) 673
Book Chapter (24) 24
Newspaper Article (9) 9
Conference Proceeding (2) 2
Dissertation (2) 2
Book / eBook (1) 1
Publication (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (479) 479
index medicus (365) 365
hutchinson-gilford-progeria (282) 282
cell biology (266) 266
animals (247) 247
progeria (211) 211
hutchinson-gilford progeria (195) 195
lamin type a - genetics (193) 193
mutation (188) 188
aging (178) 178
hutchinson-gilford progeria syndrome (178) 178
progeria - genetics (175) 175
integumentary system (141) 141
mice (130) 130
lamin type a - metabolism (119) 119
congenital, hereditary, and neonatal diseases and abnormalities (118) 118
biochemistry & molecular biology (114) 114
female (110) 110
nuclear proteins - metabolism (109) 109
male (104) 104
a-type lamins (102) 102
proteins (102) 102
progeria - metabolism (100) 100
dreifuss muscular-dystrophy (95) 95
progeria - pathology (93) 93
lamin a (91) 91
disease (90) 90
lamin (87) 87
phenotype (87) 87
laminopathies (81) 81
nutritional and metabolic diseases (81) 81
senescence (81) 81
lamins (80) 80
prelamin-a (80) 80
genetics & heredity (78) 78
protein precursors - metabolism (78) 78
geriatrics & gerontology (77) 77
fibroblasts (75) 75
nuclear-envelope (72) 72
child (71) 71
mandibuloacral dysplasia (68) 68
cells, cultured (67) 67
dilated cardiomyopathy (65) 65
expression (65) 65
mutations (65) 65
nuclear lamina (64) 64
nuclear proteins - genetics (64) 64
chromatin (63) 63
lamin type a (63) 63
cell nucleus - metabolism (61) 61
cellular senescence (60) 60
embryonic structures (60) 60
familial partial lipodystrophy (60) 60
fibroblasts - metabolism (60) 60
mouse model (60) 60
research (59) 59
adult (57) 57
genetic aspects (56) 56
lmna (55) 55
nuclear envelope (55) 55
zmpste24 (55) 55
analysis (54) 54
cells (52) 52
defects (50) 50
membrane proteins - genetics (50) 50
restrictive dermopathy (50) 50
biology (49) 49
gene expression (49) 49
lamin a/c (48) 48
protein precursors - genetics (48) 48
dna damage (46) 46
hutchinson–gilford progeria syndrome (46) 46
lamin-a (46) 46
membrane proteins - metabolism (46) 46
life sciences (45) 45
medicine, research & experimental (45) 45
prelamin a (45) 45
progerin (45) 45
aging, premature - genetics (43) 43
multidisciplinary sciences (43) 43
cell line (42) 42
in-vitro (42) 42
partial lipodystrophy (42) 42
aging - genetics (41) 41
child, preschool (41) 41
nuclear envelope - metabolism (41) 41
cancer (40) 40
progeria - physiopathology (40) 40
intermediate filament proteins (39) 39
encoding lamin a/c (38) 38
physiological aspects (38) 38
lamin a/c gene (37) 37
adolescent (36) 36
gene-expression (36) 36
genetics (36) 36
review (36) 36
signal transduction (36) 36
disease models, animal (35) 35
laminopathy (35) 35
oxidative stress (35) 35
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (692) 692
French (6) 6
German (3) 3
Polish (3) 3
Japanese (2) 2
Portuguese (2) 2
Spanish (2) 2
Chinese (1) 1
Dutch (1) 1
Korean (1) 1
Persian (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 11/2016, Volume 113, Issue 46, pp. E7250 - E7259
Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disease caused by defective prelamin A processing, leading to nuclear lamina alterations, severe cardiovascular pathology, and premature death... 
Prelamin A | Connexin43 | Hutchinson-Gilford progeria syndrome | Calcium handling | Progerin | ARRHYTHMIAS | ARRHYTHMOGENESIS | ACTIVATION | progerin | connexin43 | calcium handling | A-TYPE LAMINS | MULTIDISCIPLINARY SCIENCES | MOUSE | MECHANISMS | VENTRICULAR MYOCYTES | HEART | prelamin A | DISEASE | PROPAGATION | Metalloendopeptidases - genetics | Heart - physiology | Humans | Child, Preschool | Sarcoplasmic Reticulum - physiology | Male | Cardiac Conduction System Disease - physiopathology | Progeria - metabolism | Arrhythmias, Cardiac - physiopathology | Cardiac Conduction System Disease - metabolism | Young Adult | Calcium - physiology | Connexin 43 - physiology | Progeria - physiopathology | Membrane Proteins - physiology | Myocardium - metabolism | Adult | Female | Child | Nuclear Lamina - physiology | Arrhythmias, Cardiac - metabolism | Connexin 43 - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | Mice, Knockout | Animals | Adolescent | Metalloendopeptidases - physiology | Physiological aspects | Calcium-binding proteins | Health aspects | Progeria | Electrònica en cardiologia | Enginyeria biomèdica | Hutchinson–Gilford progeria syndrome | Electrònica mèdica | Medical electronics | Electrònica biomèdica | Àrees temàtiques de la UPC | Biological Sciences | PNAS Plus
Journal Article
Current Opinion in Genetics & Development, ISSN 0959-437X, 2014, Volume 26, pp. 41 - 46
Journal Article
Aging Cell, ISSN 1474-9718, 08/2013, Volume 12, Issue 4, pp. 533 - 543
...–Gilford progeria syndrome (HGPS), which is caused by a spontaneous mutation and characterized by premature aging... 
progerin | transcription | lamin A | Hutchinson–Gilford progeria syndrome | lamin B1 | LMNA | nuclear lamina | aging | Nuclear lamina | Lamin B1 | Transcription | Progerin | Aging | Hutchinson-Gilford progeria syndrome | Lamin A | DEFECTIVE MATURATION | STEM-CELLS | OSTEOBLAST DIFFERENTIATION | A-TYPE LAMINS | DNA-DAMAGE | CELLULAR SENESCENCE | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | GROWTH-FACTOR-BETA | RETINOBLASTOMA PROTEIN | ADIPOCYTE DIFFERENTIATION | NUCLEAR-MEMBRANE PROTEIN | Protein Precursors - genetics | Lamin Type B - genetics | Humans | Gene Silencing | Chromatin Assembly and Disassembly | Nuclear Proteins - metabolism | Lamin Type A - metabolism | Progeria - genetics | Progeria - metabolism | Lamin Type B - metabolism | Protein Precursors - metabolism | Mechanotransduction, Cellular | Adult Stem Cells - metabolism | Phenotype | Cell Nucleus - metabolism | Cell Nucleus - genetics | DNA Repair | Progeria - pathology | Lamin Type A - genetics | Transcription, Genetic | Telomere - metabolism | Adult Stem Cells - pathology | Nuclear Proteins - genetics | Telomere - genetics | DNA replication | Genetic transcription | Intermediate filament proteins | Progeria | Chromatin | Senescence | DNA damage | Cytology | Amino acids | Lamins | DNA repair | Proteins | Filaments | Cell cycle | DNA methylation | Fibroblasts | Degeneration | Deoxyribonucleic acid--DNA | Phenotypes | Intermediate filaments | Polymerization | RNA polymerase | Gene expression | DNA biosynthesis | Life span | Arteriosclerosis | Mutation | Binding sites | Apoptosis
Journal Article