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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2012, Volume 109, Issue 12, pp. 4467 - 4472
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2019, Volume 116, Issue 1, pp. 49 - 56
Amide hydrogen/deuterium exchange mass spectrometry (HDXMS) of proteins has become extremely popular for identifying ligand-binding sites, protein-protein... 
STATE | BIOPHYSICS | MOLECULAR-DYNAMICS SIMULATIONS | PATHWAY | HYDROGEN-EXCHANGE
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 46, pp. E9759 - E9760
Journal Article
Radiation Physics and Chemistry, ISSN 0969-806X, 12/2019, Volume 165, p. 108406
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2014, Volume 136, Issue 27, pp. 9564 - 9567
As part of our ongoing interest in main group Lewis acids for fluoride anion complexation and element-fluorine bond activation, we have synthesized the... 
SUPER ACIDS | CHEMISTRY | IONS | CRYSTAL | ANTIMONY PENTAFLUORIDE | DRINKING-WATER | POLYCONDENSATION | CHEMISTRY, MULTIDISCIPLINARY | HYDROGEN-EXCHANGE | CATIONS | HYDRODEFLUORINATION
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 05/2011, Volume 133, Issue 17, pp. 6505 - 6508
A critical aspect to understanding the molecular basis of Alzheimer's disease (AD) is the characterization of the kinetics of interconversion between the... 
CORE | TERMINUS | PROTEIN | ALZHEIMERS-DISEASE | BETA AGGREGATION | TOXICITY | MUTATIONS | CHEMISTRY, MULTIDISCIPLINARY | HYDROGEN-EXCHANGE | SENILE PLAQUES
Journal Article
Nature, ISSN 0028-0836, 11/2008, Volume 456, Issue 7220, pp. 350 - 356
Nuclear receptors are multi- domain transcription factors that bind to DNA elements from which they regulate gene expression. The peroxisome proliferator-... 
RESPONSE ELEMENT | DOMAIN | LIGAND-BINDING | MECHANISM | PROLIFERATOR-ACTIVATED RECEPTORS | MULTIDISCIPLINARY SCIENCES | REV-ERB-ALPHA | RETINOID-X-RECEPTOR | ALLOSTERIC CONTROL | IDENTIFICATION | HYDROGEN-EXCHANGE
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2012, Volume 51, Issue 39, pp. 9748 - 9770
Journal Article
by Xiao, CL and Xu, X and Liu, S and Wang, T and Dong, WR and Yang, TG and Sun, ZG and Dai, DX and Zhang, DH and Yang, XM
SCIENCE, ISSN 0036-8075, 07/2011, Volume 333, Issue 6041, pp. 440 - 442
Quantum dynamical theories have progressed to the stage in which state-to-state differential cross sections can now be routinely computed with high accuracy... 
QUANTUM SCATTERING | CHEMICAL-REACTIONS | HYDROGEN-EXCHANGE REACTION | MULTIDISCIPLINARY SCIENCES | CHEMISTRY | SCATTERING CALCULATIONS | REACTION DYNAMICS | 6 DIMENSIONS | RESONANCES | Atoms & subatomic particles | Chemical reactions | Quantum physics
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 05/2006, Volume 63, Issue 2, pp. 349 - 355
Hydrogen exchange results for cytochrome c and several other proteins show that they are composed of a number of foldon units which continually unfold and... 
hydrogen exchange | cytochrome c | alkaline transition | foldon | Alkaline transition | Cytochrome c | Hydrogen exchange | Foldon
Journal Article
Biochemistry, ISSN 0006-2960, 12/2012, Volume 51, Issue 49, pp. 9773 - 9775
Most theories about macromolecular crowding focus on two ideas: the macromolecular nature of the crowder and entropy. For proteins, the volume excluded by the... 
OSMOLYTE | NMR | DENATURANTS | ENZYME | BIOCHEMISTRY & MOLECULAR BIOLOGY | SOLUTES | VOLUME | DYNAMICS | BACKBONE | HYDROGEN-EXCHANGE | WATER | Thermodynamics | Macromolecular Substances - chemistry | Proteins - chemistry | Measurement | Chymotrypsin | Protein folding | Enthalpy | Chemical properties | Research | Structure | Protein binding
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2012, Volume 109, Issue 12, pp. 4467 - 4472
The misfolding of serpins is linked to several genetic disorders including emphysema, thrombosis, and dementia. During folding, inhibitory serpins are... 
POLYMERS | ORDER | hydrogen exchange | PATHWAY | MULTIDISCIPLINARY SCIENCES | misfolding disease | protein folding | POLYMERIZATION | SHEET | MOLECULAR-BASIS
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1, p. 14339
Dengue virus serotype 2 (DENV2) alone undergoes structural expansion at 37 degrees C (associated with host entry), despite high sequence and structural... 
EXCHANGE MASS-SPECTROMETRY | PROTEIN | RECOGNITION | MULTIDISCIPLINARY SCIENCES | DYNAMICS | ANTIBODY | HIGHLY POTENT | IDENTIFICATION | BINDING | NEUTRALIZATION | HYDROGEN-EXCHANGE
Journal Article
Journal of Biomolecular NMR, ISSN 0925-2738, 11/2014, Volume 60, Issue 2, pp. 109 - 129
The pK a values and charge states of ionizable residues in polypeptides and proteins are frequently determined via NMR-monitored pH titrations. To aid the... 
Biochemistry, general | Spectroscopy/Spectrometry | Chemical shift | Deuterium isotope shift | Scalar coupling | pH titration | Hydrogen exchange | Biophysics and Biological Physics | Protein electrostatics | Physics
Journal Article
ChemPhysChem, ISSN 1439-4235, 01/2019, Volume 20, Issue 2, pp. 173 - 173
The Front Cover illustrates that the strength of interactions formed by arginine side‐chains can be derived from hydrogen exchange rates. An NMR method, based... 
13C-detected NMR spectroscopy | hydrogen exchange | arginine side-chains | guanidinium interactions | protection factors | protein-protein interactions
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 07/2019, Volume 58, Issue 26, pp. 2875 - 2882
In the absence of arabinose, the dimeric Escherichia coli regulatory protein of the L-arabinose operon, AraC, represses expression by looping the DNA between... 
SYSTEM | DNA-BINDING DOMAIN | INTERDOMAIN LINKER | PROTEIN | GENE | REPRESSION | INVITRO | BIOCHEMISTRY & MOLECULAR BIOLOGY | OPERON | ARM | HYDROGEN-EXCHANGE
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2012, Volume 134, Issue 40, pp. 16614 - 16618
Journal Article