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Gynäkologische Endokrinologie, ISSN 1610-2894, 05/2020, Volume 18, Issue 2, pp. 123 - 128
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 12/2007, Volume 27, Issue 23, pp. 8330 - 8339
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Liver Function Tests | Steroid 12-alpha-Hydroxylase - metabolism | Gene Targeting | Liver - pathology | Signal Transduction | Receptors, Cytoplasmic and Nuclear - deficiency | Bile Acids and Salts - metabolism | Hepatocytes - pathology | Lipid Metabolism | Organ Specificity | Gene Expression Regulation, Enzymologic | Cholesterol 7-alpha-Hydroxylase - genetics | Steroid 12-alpha-Hydroxylase - genetics | Animals | Biological Transport | Cholesterol 7-alpha-Hydroxylase - metabolism | Membrane Transport Proteins - metabolism | Mice | Feces | Intestinal Absorption - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Steroid 12-alpha-Hydroxylase | Liver | Biochemistry, Molecular Biology | Bile Acids and Salts | Receptors, Cytoplasmic and Nuclear | Intestinal Absorption | Life Sciences | Cholesterol 7-alpha-Hydroxylase | Hepatocytes | Membrane Transport Proteins | Molecular biology
Journal Article
Molecular and cellular endocrinology, ISSN 0303-7207, 03/2014, Volume 383, Issue 1-2, pp. 111 - 117
Monoclonal antibodies | Immunofluorescence | CYP11B2 | CYP11B1 | Adrenal cortex | 17α-Hydroxylase | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Antibodies, Monoclonal - biosynthesis | Humans | Steroid 11-beta-Hydroxylase - immunology | Molecular Sequence Data | Peptides - administration & dosage | Peptides - chemical synthesis | Zona Fasciculata - immunology | Steroid 17-alpha-Hydroxylase - immunology | Adult | Cytochrome P-450 CYP11B2 - metabolism | Infant, Newborn | Amino Acid Sequence | Zona Glomerulosa - ultrastructure | Peptides - immunology | Rats | Zona Glomerulosa - metabolism | Antibodies, Monoclonal - isolation & purification | Immunohistochemistry - methods | Sequence Homology, Amino Acid | Sequence Alignment | Animals | Steroid 11-beta-Hydroxylase - metabolism | Cytochrome P-450 CYP11B2 - immunology | Zona Glomerulosa - immunology | Zona Fasciculata - metabolism | Mice | Steroid 17-alpha-Hydroxylase - metabolism | Zona Fasciculata - ultrastructure | Cytochrome P-450 | Index Medicus
Journal Article
The Journal of steroid biochemistry and molecular biology, ISSN 0960-0760, 04/2019, Volume 188, pp. 38 - 47
Metabolic flux | CYP11B2 | LC–MS/MS | Aldosterone synthase inhibitors | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Line | Drug Evaluation, Preclinical - methods | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Humans | Enzyme Inhibitors - pharmacology | Enzyme Assays - methods | Steroid 11-beta-Hydroxylase - antagonists & inhibitors | Biosynthetic Pathways - drug effects | Steroid 11-beta-Hydroxylase - metabolism | Cytochrome P-450 CYP11B2 - antagonists & inhibitors | Steroids - metabolism | Steroid 17-alpha-Hydroxylase - metabolism | Steroids - analysis | Cytochrome P-450 CYP11B2 - metabolism | Dehydroepiandrosterone | Hormones, Sex | Corticosteroids | Enzyme kinetics | Mass spectrometry | Cytochrome P-450 | Corticosterone | Hydroxylase | Aldosterone synthase | Homology | Hydrocortisone | Aldosterone | Steroid 11β-hydroxylase | Perfusion | Computer applications | Steroidogenesis | Intracellular | Steroid hormones | Index Medicus
Journal Article
Human reproduction (Oxford), ISSN 0268-1161, 5/2010, Volume 25, Issue 5, pp. 1303 - 1311
Testis | Reproduction | CYP | Hydroxylase | Vitamin D receptor | Life Sciences & Biomedicine | Obstetrics & Gynecology | Reproductive Biology | Science & Technology | Epididymis - metabolism | Immunohistochemistry | Steroid Hydroxylases - metabolism | Testis - metabolism | Seminal Vesicles - metabolism | Spermatogenesis | Humans | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Male | DNA Primers - genetics | Spermatozoa - metabolism | RNA, Messenger - metabolism | Prostate - metabolism | Tissue Distribution | Cytochrome P450 Family 2 | Base Sequence | Adult | Steroid Hydroxylases - genetics | Gene Expression | RNA, Messenger - genetics | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Rats | Vitamin D3 24-Hydroxylase | Genitalia, Male - metabolism | Receptors, Calcitriol - metabolism | Animals | Cholestanetriol 26-Monooxygenase - genetics | Cholestanetriol 26-Monooxygenase - metabolism | Vitamin D - metabolism | Mice | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 03/2019, Volume 294, Issue 12, pp. 4359 - 4367
protein structure | analytical ultracentrifugation | enzyme stability | phenylalanine hydroxylase | small-angle X-ray scattering (SAXS) | protein conformation | allosteric regulation | phenylketonuria | hydroxylase | enzyme kinetics | allostery | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Phenylalanine Hydroxylase - genetics | Allosteric Regulation | Electrophoresis, Polyacrylamide Gel | Enzyme Stability | Scattering, Small Angle | Spectrometry, Fluorescence | Ultracentrifugation | X-Ray Diffraction | Phenylketonurias - metabolism | Protein Conformation | Kinetics | Mutation | Phenylalanine Hydroxylase - chemistry | Phenylalanine Hydroxylase - metabolism | Index Medicus | Enzymology
Journal Article
Journal of lipid research, ISSN 0022-2275, 06/2009, Volume 50, Issue 6, pp. 1090 - 1100
Cholesterol 7α-hydroxylase | Sterol 12 α-hydroxylase | Atherosclerosis | Small heterodimer partner | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Dyslipidemias - genetics | Apolipoproteins E - deficiency | Gene Expression - drug effects | Steroid 12-alpha-Hydroxylase - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - deficiency | Atherosclerosis - genetics | Male | Lipids - blood | Receptors, LDL - deficiency | Dyslipidemias - prevention & control | Female | Indoles - pharmacology | Receptors, LDL - genetics | Atherosclerosis - pathology | Mice, Inbred C57BL | Bile Acids and Salts - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Atherosclerosis - metabolism | Mice, Knockout | Azepines - pharmacology | Cholesterol 7-alpha-Hydroxylase - genetics | Steroid 12-alpha-Hydroxylase - genetics | Animals | Apolipoproteins E - genetics | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Dyslipidemias - metabolism | Mice | Cholesterol 7-alpha-Hydroxylase - antagonists & inhibitors | Atherosclerosis - prevention & control | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | atherosclerosis | small heterodimer partner | sterol 12 α-hydroxylase | cholesterol 7α-hydroxylase
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 11/2015, Volume 20, Issue 11, pp. 20551 - 20568
High-throughput screening (HTS) | Structure-based drug design (SBDD) | Prolyl hydroxylase (PHD) inhibitor | Hypoxia-inducible factor (HIF) | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Prolyl Hydroxylases - metabolism | Prolyl-Hydroxylase Inhibitors - pharmacology | Humans | Molecular Conformation | Ischemia - metabolism | Drug Discovery - methods | Structure-Activity Relationship | Enzyme Activation - drug effects | Hypoxia - metabolism | Prolyl-Hydroxylase Inhibitors - therapeutic use | Prolyl-Hydroxylase Inhibitors - chemistry | Anemia - metabolism | Inflammation - metabolism | Anemia - drug therapy | Animals | High-Throughput Screening Assays | Ischemia - drug therapy | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Inflammation - drug therapy | Prolyl Hydroxylases - chemistry | Protein Binding | Protein Interaction Domains and Motifs | Drug Evaluation, Preclinical | Index Medicus | structure-based drug design (SBDD) | prolyl hydroxylase (PHD) inhibitor | hypoxia-inducible factor (HIF) | high-throughput screening (HTS)
Journal Article
Human mutation, ISSN 1059-7794, 04/2019, Volume 40, Issue 4, pp. 444 - 457
proteasome | protein unfolding | PAH | genotype–phenotype | PKU | protein stability | protein degradation | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Phenylalanine Hydroxylase - genetics | Cell Line | Genetic Predisposition to Disease | Phenylketonurias - diagnosis | Phenylketonurias - genetics | Humans | Genetic Association Studies - methods | Models, Molecular | Genotype | Structure-Activity Relationship | Phenylalanine Hydroxylase - blood | Alleles | Protein Conformation | Enzyme Activation | Mutation | Proteasome Endopeptidase Complex - metabolism | Protein Stability | Phenylalanine Hydroxylase - chemistry | Proteins | Medical research | Phenylalanine | Proteolysis | Analysis | Denaturation | Medicine, Experimental | Genetic aspects | Hydroxylases | Sapropterin dihydrochloride | Cells | Phenylketonuria | Neurotoxicity | Phenotypes | Phenylalanine 4-monooxygenase | Tetrahydrobiopterin | Hydroxylase | Proteasomes | Localization | Genotypes | Proteasome inhibitors | Index Medicus
Journal Article
The New England journal of medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 4, pp. 338 - 351
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Prednisolone - adverse effects | Steroid 17-alpha-Hydroxylase - antagonists & inhibitors | Prostatic Neoplasms - radiotherapy | Prednisolone - administration & dosage | Prostatic Neoplasms - surgery | Humans | Middle Aged | Abiraterone Acetate - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Neoplasm Recurrence, Local - drug therapy | Male | Prostate-Specific Antigen - blood | Prostatic Neoplasms - mortality | Abiraterone Acetate - administration & dosage | Neoplasm Metastasis - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Aged, 80 and over | Adult | Aged | Androgen Antagonists - administration & dosage | Androgen Antagonists - adverse effects | Prostatic Neoplasms - drug therapy | Androgen suppression therapy | Usage | Care and treatment | Prostate cancer | Prednisolone | Medical research | Prostate-specific antigen | Clinical trials | Endocrine therapy | Oncology | Metastasis | Radiation therapy | Cancer therapies | Metastases | Mens health | Androgens | Medical prognosis | Death | Prostate | Index Medicus | Abridged Index Medicus
Journal Article