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OPHTHALMOLOGE, ISSN 0941-293X, 05/2018, Volume 115, Issue 5, pp. 433 - 450
Dry eye disease (DED) is one of the most common ophthalmological diseases with an increasing prevalence in recent years. Numerous general and ocular risk... 
DEFINITION | POPULATION | Neurosensory abnormalities | Diagnostics | MEIBOMIAN GLAND DYSFUNCTION | SJOGRENS-SYNDROME | CLASSIFICATION | Inflammation | LASIK | THERAPEUTIC MANAGEMENT | Hyperosmolarity | SUBCOMMITTEE | OPHTHALMOLOGY | DRYNESS SYMPTOMS | Symptom questionnaire | EPIDEMIOLOGY | Eye | Surveys and Questionnaires | Dry Eye Syndromes | Humans | Tears
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2017, Volume 118, Issue 11, pp. 3883 - 3890
ABSTRACT Among Neuronal Ceroid Lipofuscinoses (NCLs), which are childhood fatal neurodegenerative disorders, the juvenile onset form (JNCL) is the most common.... 
CATHEPSIN D | SAPOSINS | HYPEROSMOLARITY | PROSAPOSIN | BATTEN DISEASE | NEURONAL CEROID LIPOFUSCINOSES | CLN3 DISEASE | CELLS | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | SAPOSIN-A | CELL BIOLOGY | JUVENILE BATTEN-DISEASE | PATHWAY | DEGRADATION | MUTATIONS | NEURONAL CEROID-LIPOFUSCINOSIS | Cell Line | Cricetinae | Lysosome-Associated Membrane Glycoproteins - metabolism | Molecular Chaperones - metabolism | Membrane Glycoproteins - metabolism | Humans | Lysosomes - genetics | Molecular Chaperones - genetics | Neuronal Ceroid-Lipofuscinoses - metabolism | Saposins - genetics | Cathepsin D - metabolism | Neuronal Ceroid-Lipofuscinoses - pathology | Membrane Glycoproteins - genetics | Saposins - metabolism | Animals | Lysosomes - metabolism | Neuronal Ceroid-Lipofuscinoses - genetics | Cathepsin D - genetics | Lysosome-Associated Membrane Glycoproteins - genetics | Lysosomes - pathology | Cathepsins | Physiological aspects | Nervous system diseases | Analysis | Neurodegenerative diseases | Syngeneic grafts | Lysosomes | mRNA | Myc protein | Gene expression | Metabolism | Cofactors | Protein turnover | Western blotting | Membrane proteins | Proteins | CLN3 protein | Proteolysis | Cathepsin D | Neuronal ceroid lipofuscinosis | Children | Lipid metabolism | Mutation | Osmotic pressure | Kidney transplantation | prosaposin | CLN3 disease | cathepsin D | Neuronal Ceroid Lipofuscinoses | hyperosmolarity | saposins | Batten disease
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 09/2018, Volume 1863, Issue 9, pp. 1108 - 1120
Hyperosmolarity is a controversial signal for renal cells. It can induce cell stress or differentiation and both require an active lipid metabolism. We showed... 
Lipin | DGAT | Triglyceride storage | SREBP | Phospholipid synthesis | Hyperosmolarity | LIPID-METABOLISM | REGULATORY VOLUME INCREASE | PHOSPHATASE ENZYMES | RAT-KIDNEY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TONEBP TRANSCRIPTIONAL ACTIVATOR | FATTY-ACIDS | CELL BIOLOGY | BIOPHYSICS | EPITHELIAL-CELLS | PHOSPHOLIPID BIOSYNTHESIS | TRIGLYCERIDE SYNTHESIS | HEPATIC STEATOSIS | Fatty Acid Synthase, Type I - genetics | Osmotic Pressure | Triglycerides - biosynthesis | Sodium Chloride - pharmacology | Phosphatidate Phosphatase - metabolism | Phosphatidate Phosphatase - genetics | Acetyl-CoA Carboxylase - genetics | Osmolar Concentration | Diglycerides - metabolism | Isoenzymes - metabolism | Madin Darby Canine Kidney Cells | Cell Membrane - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Homeostasis - drug effects | Phospholipids - metabolism | Sterol Regulatory Element Binding Protein 2 - metabolism | Fatty Acids - metabolism | Cell Membrane - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Signal Transduction | Isoenzymes - genetics | Fatty Acid Synthase, Type I - metabolism | Gene Expression Regulation - drug effects | Animals | Diacylglycerol O-Acyltransferase - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Dogs | Phosphatidic Acids - metabolism | Diacylglycerol O-Acyltransferase - metabolism | Acetyl-CoA Carboxylase - metabolism | Homeostasis - genetics | Phosphatases | Synthesis | Homeostasis | Physiological aspects | Lipids | Fatty acids | Protein binding
Journal Article
Journal of Veterinary Internal Medicine, ISSN 0891-6640, 09/2002, Volume 16, Issue 5, pp. 510 - 517
Nephrogenic diabetes insipidus is caused by an inability of the kidney to concentrate urine despite adequate concentration of vasopressin in blood and is... 
Aquaporin | Vasopressin | Hyperosmolarity | Hyperosmolanty
Journal Article
Clinical Ophthalmology, ISSN 1177-5467, 03/2018, Volume 12, pp. 453 - 461
Dry Eye Disease (DED) is a multifactorial disease, with a high prevalence, that can have a great impact on the quality of life of patients. The first step of... 
Osmoprotectants | Artificial tears | Hyaluronic acid | Dry eye disease | Carmellose | Hyperosmolarity | Usage | Care and treatment | Ophthalmic drugs | Analysis | Eye diseases | Ophthalmology | Cataracts | Acids | Cellulose | Homeostasis | International conferences | Inflammation | Eye surgery | Patients | Quality of life
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 06/2012, Volume 53, Issue 7, pp. 3280 - 3285
PURPOSE. Reduced tear film stability is reported to contribute to dry eye. Rabbits are known to have a more stable tear film than humans. Thus, we sought to... 
OCULAR SURFACE | HYPEROSMOLARITY | INSTABILITY | OSMOLALITY | OPHTHALMOLOGY | PHOSPHOLIPIDS | VISCOSITY | MODEL | PROTEINS | OSMOLARITY | Rabbits | Surface Tension | Tears - chemistry | Cations, Divalent - analysis | Humans | Male | Reference Values | Animals | Osmolar Concentration | Lacrimal Apparatus - secretion | Mass Spectrometry | Adult | Female
Journal Article
Experimental Eye Research, ISSN 0014-4835, 03/2013, Volume 108, pp. 33 - 41
Journal Article
The Ocular Surface, ISSN 1542-0124, 01/2019, Volume 17, Issue 1, pp. 89 - 97
To investigate the ocular inflammatory response, using clinical and immunological techniques, in people experiencing contact lens (CL) discomfort. This study... 
Tear film | Contact lens discomfort | IL-17A | Contact lens | Interleukin | Cytokine | Inflammation | Ocular surface | SILICONE HYDROGEL | TFOS INTERNATIONAL WORKSHOP | NERVE GROWTH-FACTOR | CORNEAL | HYPEROSMOLARITY | DRY EYE | LANGERHANS CELL-DENSITY | WEAR | OPHTHALMOLOGY | OSMOLARITY | Usage | Dry eye syndromes | Cytokines | Contact lenses | Development and progression | Diagnosis | Health aspects
Journal Article