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CANCER RESEARCH, ISSN 0008-5472, 10/2005, Volume 65, Issue 19, pp. 8635 - 8639
DNA methyttransferase 1 (DNMT1)-deficient mice are tumor-prone, and this has been proposed to result from the induction of genomic instability. To address... 
INACTIVATION | METHYLATION | ONCOLOGY | DNMT3B | HYPOMETHYLATION
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 06/2018, Volume 46, Issue 11, pp. 5504 - 5524
Abstract Primate-specific NBL2 macrosatellite is hypomethylated in several types of tumors, yet the consequences of this DNA hypomethylation remain unknown. We... 
CELLS | METHYLATION | GENOMIC HYPOMETHYLATION | DNA HYPOMETHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN HEPATOCELLULAR-CARCINOMA | BINDING PROTEIN | TUMORS | REPEATS | GU-RICH ELEMENTS | REPETITIVE DNA | Gene regulation, Chromatin and Epigenetics
Journal Article
Artificial Cells, Nanomedicine, and Biotechnology, ISSN 2169-1401, 12/2019, Volume 47, Issue 1, pp. 2500 - 2506
Angiotensin I-Converting Enzyme (ACE, CD143) Gene plays a crucial role in the pathology of carcinomas in many cancers including colorectal cancer (CRC).... 
cell growth | colorectal cancer | prognosis | ACE hypomethylation
Journal Article
Meta Gene, ISSN 2214-5400, 12/2018, Volume 18, pp. 62 - 67
Gallbladder cancer (GBC) is the most lethal orphan malignancy of biliary tract, with poor prognosis and varied global incidences, predominately reported from,... 
Biomarker | Hypomethylation | S100A9 | Gallbladder cancer
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2016, Volume 94, Issue 2
ABSTRACT Nicotine significantly promoted apoptosis in stages I, VII, VIII, and XI spermatogonia, stages I, VII, VIII, X, and XI spermatocytes, and stages I–V,... 
Trim27 hypomethylation | apoptosis | RIP1 deubiquitination | nicotine | spermatozoa
Journal Article
DNA Repair, ISSN 1568-7864, 06/2019, Volume 78, pp. 70 - 80
Increasing evidence supports the role of genetic and epigenetic alterations in a wide variety of human diseases, including cancer. Assessment of these... 
Carcinogen | Clastogen | Aneugen | DNA damage and repair | DNA hypomethylation
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 04/2019, Volume 134, pp. 419 - 428
Oxidative stress and reactivation of long interspersed element-1 (LINE-1) are coincidently observed in bladder cancer (BlCa), but the mechanistic connection... 
LINE-1 | Oxidative stress | Histone modification | Bladder cancer | DNA hypomethylation | 8-OHdG | METHYLATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | HALLMARK | HYPOMETHYLATION | HISTONE H3 | ENDOCRINOLOGY & METABOLISM | ATM ACTIVATION | LYSINE 9 | EXPRESSION | Chromatin | Methylation
Journal Article
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 01/2013, Volume 5, Issue 169
Human cancers almost ubiquitously harbor epigenetic alterations. Although such alterations in epigenetic marks, including DNA methylation, are potentially... 
MEDICINE, RESEARCH & EXPERIMENTAL | INSTABILITY | BENIGN | INTESTINAL NEOPLASIA | HYPERPLASIA | SUPPRESSION | EXPRESSION | CPG-ISLAND HYPERMETHYLATION | PROGRESSION | HYPOMETHYLATION | TRANSFERASE | CELL BIOLOGY
Journal Article
Genome Biology, ISSN 1474-7596, 12/2014, Volume 15, Issue 11, pp. 503 - 503
We propose an extension to quantile normalization that removes unwanted technical variation using control probes. We adapt our algorithm, functional... 
Method
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2012, Volume 18, Issue 2, pp. 224 - 226
Although aberrant DNA methylation is considered to be one of the key ways by which tumor-suppressor and DNA-repair genes are silenced during tumor initiation... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENOTYPE | CPG | METHYLTRANSFERASE EXPRESSION | CANCER | HYPOMETHYLATION | CELL BIOLOGY
Journal Article
Experimental Neurology, ISSN 0014-4886, 10/2019, Volume 320, pp. 113011 - 113011
Aberrant expression of , a gene unique to humans and primates, causes Facioscapulohumeral Muscular Dystrophy-1 (FSHD), yet the pathogenic mechanism is unknown....