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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 03/2016, Volume 193, Issue 5, pp. 504 - 515
Rationale: Cystic fibrosis (CF) is characterized by early structural lung disease caused by pulmonary infections. The nasopharynx of infants is a major... 
Healthy controls | Cystic fibrosis | Microbiota | Nasopharynx | Longitudinal | microbiota | SMALL-COLONY VARIANTS | CARRIAGE | HAEMOPHILUS-INFLUENZAE | COMMUNITIES | CHILDREN | STREPTOCOCCUS-PNEUMONIAE | INHIBITION | RESPIRATORY SYSTEM | cystic fibrosis | INFLAMMATION | LUNG-DISEASE | STAPHYLOCOCCUS-AUREUS | longitudinal | nasopharynx | healthy controls | CRITICAL CARE MEDICINE | Carrier State - epidemiology | Streptococcus mitis - genetics | Prospective Studies | Humans | Corynebacterium Infections - epidemiology | Carrier State - microbiology | Haemophilus Infections - epidemiology | Infant | Male | Corynebacterium Infections - microbiology | Case-Control Studies | Anti-Bacterial Agents - therapeutic use | Enterobacteriaceae Infections - epidemiology | Female | Staphylococcal Infections - microbiology | Nasopharynx - microbiology | Real-Time Polymerase Chain Reaction | Burkholderia Infections - microbiology | Haemophilus Infections - drug therapy | Infant, Newborn | Staphylococcus aureus - genetics | Moraxellaceae Infections - epidemiology | Streptococcal Infections - microbiology | Burkholderia - genetics | Staphylococcal Infections - drug therapy | Burkholderia Infections - epidemiology | Cystic Fibrosis - microbiology | Enterobacteriaceae Infections - microbiology | Enterobacteriaceae - genetics | Moraxellaceae Infections - microbiology | Streptococcal Infections - epidemiology | Haemophilus influenzae - genetics | Corynebacterium - genetics | Cystic Fibrosis - epidemiology | Moraxellaceae Infections - drug therapy | DNA, Bacterial - genetics | Staphylococcal Infections - epidemiology | Corynebacterium Infections - drug therapy | Microbiota - genetics | Burkholderia Infections - drug therapy | Haemophilus Infections - microbiology | RNA, Ribosomal, 16S - genetics | Streptococcal Infections - drug therapy | Moraxella - genetics | Cohort Studies | Enterobacteriaceae Infections - drug therapy
Journal Article
Respiratory Medicine, ISSN 0954-6111, 2016, Volume 117, pp. 190 - 197
Abstract Objectives In airway infections, biofilm formation has been demonstrated to be responsible for both acute and chronic events, and constitutes a... 
Pulmonary/Respiratory | Biofilm | Inhaled formulation | Airways infections | Topical administration | N-acetylcysteine | NONTYPABLE HAEMOPHILUS-INFLUENZAE | CARDIAC & CARDIOVASCULAR SYSTEMS | COMBINATION | BACTERIAL BIOFILMS | IN-VITRO | STREPTOCOCCUS-PNEUMONIAE | PSEUDOMONAS-AERUGINOSA INFECTION | RESPIRATORY SYSTEM | EXACERBATIONS | ACETYL-L-CYSTEINE | STAPHYLOCOCCUS-AUREUS | THIAMPHENICOL GLYCINATE | Biofilms - drug effects | Bronchiectasis - drug therapy | Humans | Biofilms - growth & development | Administration, Inhalation | Respiratory Tract Infections - drug therapy | Injections, Intramuscular | Pulmonary Disease, Chronic Obstructive - complications | Cystic Fibrosis - complications | Bronchitis, Chronic - drug therapy | Bronchiectasis - complications | Bronchitis - drug therapy | Bronchitis, Chronic - complications | Expectorants - therapeutic use | Acetylcysteine - pharmacology | Bronchitis - complications | Respiratory Tract Infections - complications | Acetylcysteine - administration & dosage | Cystic Fibrosis - drug therapy | Pulmonary Disease, Chronic Obstructive - drug therapy | Acetylcysteine | Respiratory tract diseases | Drug therapy | Health aspects | Pathogens | Pneumonia | Biofilms | Antibiotics | Ear diseases | Cystic fibrosis | Bacteria | Staphylococcus infections | Chronic obstructive pulmonary disease | Bronchitis | Streptococcus infections
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 519 - 532
Background Severe steroid-insensitive asthma is a substantial clinical problem. Effective treatments are urgently required, however, their development is... 
Allergy and Immunology | influenza | airway hyperresponsiveness | corticosteroids | PI3 kinase | Chlamydia species | histone deacetylase 2 | Severe asthma | miR-21 | respiratory syncytial virus | Haemophilus influenzae | IMMUNE-RESPONSE | INFLAMMATORY RESPONSES | ALLERGIC AIRWAYS DISEASE | TENSIN HOMOLOG | IMMUNOLOGY | RESPIRATORY-INFECTION | NEUTROPHILIC ASTHMA | OBSTRUCTIVE PULMONARY-DISEASE | Chlamydia | INFLUENZA-VIRUS INFECTION | ALLERGY | species | REGULATORY T-CELLS | BACTERIAL-INFECTION | Influenza A Virus, H1N1 Subtype - immunology | Phosphorylation | Humans | Respiratory Syncytial Viruses - immunology | MicroRNAs - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Respiratory Tract Infections - genetics | Chlamydia muridarum - immunology | Asthma - immunology | Pneumonia - immunology | Proto-Oncogene Proteins c-akt - metabolism | Drug Resistance | Disease Models, Animal | Pneumonia - genetics | Histone Deacetylase 2 - genetics | PTEN Phosphohydrolase - genetics | Gene Expression Regulation | PTEN Phosphohydrolase - metabolism | Respiratory Tract Infections - drug therapy | Asthma - drug therapy | Asthma - genetics | Dexamethasone - therapeutic use | Animals | Pneumonia - drug therapy | Haemophilus influenzae - immunology | Respiratory Tract Infections - immunology | Mice | Mice, Inbred BALB C | MicroRNAs - genetics | Histone Deacetylase 2 - metabolism | Antagomirs - genetics | MicroRNA | Research institutes | Analysis | Asthma | Therapeutics | Health aspects | Homeopathy | Materia medica and therapeutics | Respiratory syncytial virus | Pathogenesis | Rodents | Influenza | Tumor necrosis factor-TNF | Chronic obstructive pulmonary disease | Infections | Inflammation | Viral infections | Steroids
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2014, Volume 58, Issue 2, pp. 1127 - 1135
Journal Article
Cornea, ISSN 0277-3740, 12/2010, Volume 29, Issue 12, pp. 1353 - 1358
Journal Article
BMC Infectious Diseases, ISSN 1471-2334, 08/2016, Volume 16, Issue 1, p. 377
Background: After the concept of healthcare associated pneumonia (HCAP) was introduced in 2005 by the American Thoracic Society/Infectious Disease Society of... 
Hemodialysis | Drug resistant pathogens | Pneumonia | UNITED-STATES | MORTALITY | INFECTIOUS DISEASES | COMMUNITY-ACQUIRED PNEUMONIA | HOSPITALIZED-PATIENTS | MULTICENTER | BACTERIA | CARE-ASSOCIATED PNEUMONIA | THERAPY | CITROBACTER INFECTIONS | Age Factors | Pneumonia, Staphylococcal - epidemiology | Humans | Middle Aged | Drug Resistance, Bacterial | Haemophilus Infections - epidemiology | Male | Pneumonia, Staphylococcal - microbiology | Wounds and Injuries - epidemiology | Case-Control Studies | Haemophilus influenzae | Methicillin-Resistant Staphylococcus aureus | Gram-Negative Bacterial Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Enterobacteriaceae Infections - epidemiology | Wounds and Injuries - therapy | Aged, 80 and over | Female | Pseudomonas aeruginosa | Retrospective Studies | Citrobacter | Haemophilus Infections - drug therapy | Cross Infection - epidemiology | Severity of Illness Index | Pneumonia - epidemiology | Pseudomonas Infections - drug therapy | Enterobacteriaceae Infections - microbiology | Risk Factors | Gram-Negative Bacterial Infections - drug therapy | Hospitalization | Pneumonia - microbiology | Pseudomonas Infections - microbiology | Kidney Failure, Chronic - therapy | Pneumonia, Staphylococcal - drug therapy | Pneumonia - drug therapy | Kidney Failure, Chronic - epidemiology | Pseudomonas Infections - epidemiology | Taiwan - epidemiology | Haemophilus Infections - microbiology | Gram-Negative Bacterial Infections - epidemiology | Aged | Enterobacteriaceae Infections - drug therapy | Renal Dialysis | Pathogenic microorganisms | Bacterial pneumonia | Analysis | Research | Risk factors | Infectious diseases
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 2001, Volume 163, Issue 6, pp. 1371 - 1375