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Journal Article
Head & Neck, ISSN 1043-3074, 11/2015, Volume 37, Issue 11, pp. 1603 - 1611
Background Amidst a rising incidence of p16‐positive (p16+) oropharyngeal cancer, a significant number of cases present as regionally metastatic disease with... 
transoral laser microsurgery (TLM) | transoral robotic surgery (TORS) | human papillomavirus (HPV) | unknown primary | p16 | Transoral robotic surgery (TORS) | Human papillomavirus (HPV) | Unknown primary | P16 | Transoral laser microsurgery (TLM) | SURGERY | PRIMARY TUMORS | DIAGNOSIS | ROBOTIC SURGERY | PRIMARY ORIGIN | CANCER | CHEMOTHERAPY | LYMPH-NODE METASTASES | OTORHINOLARYNGOLOGY | SQUAMOUS-CELL CARCINOMA | LOCALLY ADVANCED HEAD | OCCULT HEAD | Oropharyngeal Neoplasms - therapy | Head and Neck Neoplasms - secondary | Head and Neck Neoplasms - virology | Follow-Up Studies | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Tumor Virus Infections - diagnosis | Male | Oropharyngeal Neoplasms - pathology | Papillomavirus Infections - diagnosis | Papillomavirus Infections - therapy | Tongue Neoplasms - virology | Tumor Virus Infections - therapy | Adult | Female | Databases, Factual | Tongue Neoplasms - mortality | Neoplasms, Unknown Primary - surgery | Chemoradiotherapy - methods | Risk Assessment | Tongue Neoplasms - therapy | Head and Neck Neoplasms - therapy | Kaplan-Meier Estimate | Treatment Outcome | Tumor Virus Infections - mortality | Combined Modality Therapy | Oropharyngeal Neoplasms - virology | Neoplasms, Unknown Primary - mortality | Papillomaviridae - isolation & purification | Tongue Neoplasms - pathology | Disease-Free Survival | Natural Orifice Endoscopic Surgery - methods | Survival Analysis | Aged | Head and Neck Neoplasms - mortality | Microsurgery - methods | Cohort Studies | Neoplasms, Unknown Primary - pathology | Papillomaviruses | Papillomavirus infections
Journal Article
Cancer, ISSN 0008-543X, 04/2016, Volume 122, Issue 8, pp. 1201 - 1208
BACKGROUND The incidence of p16 overexpression and the role of human papillomavirus (HPV) in cutaneous head and neck squamous cell carcinoma (cHNSCC) are... 
unknown primary neoplasms | squamous cell neoplasms | head and neck cancer | skin neoplasms | papillomavirus infections | human p16 protein | P16 EXPRESSION | ONCOLOGY | OROPHARYNGEAL CANCER | ACTINIC KERATOSES | P16(INK4A) | NONMELANOMA SKIN CANCERS | Head and Neck Neoplasms - secondary | Head and Neck Neoplasms - virology | Lymph Nodes - pathology | Age Factors | Follow-Up Studies | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Male | Cyclin-Dependent Kinase Inhibitor p16 | Papillomavirus Infections - pathology | Carcinoma, Squamous Cell - mortality | Time Factors | Skin Neoplasms - mortality | Statistics, Nonparametric | Aged, 80 and over | Female | Papillomavirus Infections - virology | Retrospective Studies | Neoplasm Proteins - genetics | Databases, Factual | Neoplasms, Unknown Primary - genetics | Risk Assessment | Kaplan-Meier Estimate | Proportional Hazards Models | Lymphatic Metastasis | Neoplasms, Unknown Primary - mortality | Skin Neoplasms - virology | Sex Factors | Skin Neoplasms - secondary | Survival Analysis | Carcinoma, Squamous Cell - secondary | Aged | Head and Neck Neoplasms - mortality | Human papillomavirus 16 - genetics | Cohort Studies | Neoplasms, Unknown Primary - pathology | Care and treatment | Analysis | Outcome and process assessment (Health Care) | Head and neck cancer | Diagnosis | Research | Gene expression
Journal Article
The Journal of Pathology, ISSN 0022-3417, 03/2011, Volume 223, Issue 4, pp. 482 - 495
MicroRNA‐200c (miR200c) is emerging as an important regulator of tumourigenicity and cancer metastasis with a strong capacity for inducing... 
miR200c | epithelial–mesenchymal transition | cancer stem cells | BMI1 | metastasis | head and neck squamous cell carcinoma | epithelial-mesenchymal transition | CANCER-CELLS | INITIATING CELLS | INCREASED EXPRESSION | ALDEHYDE DEHYDROGENASE 1 | DOWN-REGULATION | E-CADHERIN | PATHOLOGY | REPRESSORS ZEB1 | TONGUE | ONCOLOGY | POOR-PROGNOSIS | Aldehyde Dehydrogenase - analysis | Neoplastic Stem Cells - drug effects | Humans | Middle Aged | Male | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Neoplasms, Squamous Cell - pathology | Repressor Proteins - metabolism | Cell Survival - drug effects | Head and Neck Neoplasms - therapy | Repressor Proteins - genetics | Lymphatic Metastasis | Neoplasms, Squamous Cell - therapy | Head and Neck Neoplasms - pathology | Carcinoma, Squamous Cell | Hyaluronan Receptors - analysis | Polycomb Repressive Complex 1 | Neoplasms, Squamous Cell - genetics | Mice, Nude | RNA, Neoplasm - genetics | Carcinoma - genetics | Head and Neck Neoplasms - genetics | Mice | Mice, Inbred BALB C | MicroRNAs - genetics | Isoenzymes - analysis | Head and Neck Neoplasms - secondary | Neoplasm Proteins - metabolism | Retinal Dehydrogenase | Squamous Cell Carcinoma of Head and Neck | Adult | Female | Neoplasms, Squamous Cell - secondary | Carcinoma - pathology | Nuclear Proteins - genetics | Gene Expression Regulation, Neoplastic - physiology | Carcinoma - secondary | Neoplastic Stem Cells - radiation effects | Proto-Oncogene Proteins - metabolism | Mutagenesis, Site-Directed | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Cell Survival - radiation effects | Cell Transformation, Neoplastic - metabolism | Xenograft Model Antitumor Assays | Animals | Carcinoma - therapy | Aged | Genetic Therapy - methods | E-Cadherin | Index Medicus
Journal Article
Head & Neck, ISSN 1043-3074, 12/2015, Volume 37, Issue 12, pp. 1808 - 1815
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2016, Volume 108, Issue 4
Journal Article
Head & Neck, ISSN 1043-3074, 11/2013, Volume 35, Issue 11, pp. 1527 - 1533
Background Human papillomavirus (HPV) positivity (+) has been used to identify oropharyngeal squamous carcinomas (SCCs) presenting as unknown primaries in the... 
unknown primary | p16 | cutaneous squamous carcinoma | neck metastases | SURGERY | P16(INK4A) OVEREXPRESSION | SITE | TUMOR-SUPPRESSOR GENE | HUMAN-PAPILLOMAVIRUS | CELL CARCINOMA | RADIATION-THERAPY | ORIGIN | OTORHINOLARYNGOLOGY | OROPHARYNGEAL CANCER | PROTEIN EXPRESSION | CERVICAL LYMPH-NODES | Immunohistochemistry | Head and Neck Neoplasms - secondary | Head and Neck Neoplasms - virology | Prognosis | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Skin Neoplasms - chemistry | Male | Oropharyngeal Neoplasms - secondary | Cyclin-Dependent Kinase Inhibitor p16 | Papillomavirus Infections - pathology | Head and Neck Neoplasms - chemistry | Human papillomavirus 16 - isolation & purification | Neoplasms, Unknown Primary - chemistry | Carcinoma, Squamous Cell - mortality | Skin Neoplasms - mortality | Aged, 80 and over | Adult | Female | Retrospective Studies | Databases, Factual | Skin Neoplasms - pathology | Risk Assessment | Biomarkers, Tumor - analysis | Neoplasms, Unknown Primary - virology | Carcinoma, Squamous Cell - chemistry | Oropharyngeal Neoplasms - virology | Neoplasms, Unknown Primary - mortality | Papillomavirus Infections - genetics | Disease-Free Survival | Survival Analysis | Carcinoma, Squamous Cell - secondary | Neoplasm Proteins - analysis | Oropharyngeal Neoplasms - chemistry | Aged | Biopsy, Needle | Head and Neck Neoplasms - mortality | Human papillomavirus 16 - genetics | Neoplasms, Unknown Primary - pathology | Squamous cell carcinoma | Metastasis | Papillomavirus infections | Analysis
Journal Article
Journal Article
Head & Neck, ISSN 1043-3074, 11/2013, Volume 35, Issue 11, pp. 1521 - 1526
Background Carcinoma of unknown primary (CUP) of the neck are heterogeneous tumors in their clinical and biological characteristics, and a preoperative... 
p16 / EGFR | carcinoma of unknown primary (CUP) | identification of primary cancer | oropharynx | prognosis | p16/EGFR | SURGERY | HEAD | PRIMARY TUMOR | IN-SITU HYBRIDIZATION | HUMAN-PAPILLOMAVIRUS | PREVALENCE | TONSILLAR CARCINOMAS | EGFR | NECK-CANCER | LYMPH-NODE METASTASES | p16 | DNA | OTORHINOLARYNGOLOGY | SQUAMOUS-CELL CARCINOMAS | Immunohistochemistry | Oropharyngeal Neoplasms - therapy | Head and Neck Neoplasms - secondary | Prognosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Oropharyngeal Neoplasms - mortality | Male | Oropharyngeal Neoplasms - secondary | Cyclin-Dependent Kinase Inhibitor p16 | Head and Neck Neoplasms - chemistry | Neoplasms, Unknown Primary - chemistry | Receptor, Epidermal Growth Factor - metabolism | Statistics, Nonparametric | Aged, 80 and over | Adult | Female | Retrospective Studies | Chemoradiotherapy - methods | Risk Assessment | Biomarkers, Tumor - analysis | Head and Neck Neoplasms - therapy | Combined Modality Therapy | Neoplasms, Unknown Primary - mortality | Disease-Free Survival | Neoplasms, Unknown Primary - therapy | Survival Analysis | Neoplasm Proteins - analysis | Oropharyngeal Neoplasms - chemistry | Aged | Biopsy, Needle | Head and Neck Neoplasms - mortality | Cohort Studies | Neck Dissection | Neoplasms, Unknown Primary - pathology | Epidermal growth factor | Diagnosis | Analysis | Cancer | Medical research | Human papillomavirus
Journal Article