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Circulation, ISSN 0009-7322, 2010, Volume 121, Issue 8, pp. 963 - 972
Journal Article
Circulation, ISSN 0009-7322, 01/2007, Volume 115, Issue 3, pp. 310 - 318
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2010, Volume 160, Issue 1, pp. 60 - 76
Background and purpose:  The regulatory guidelines (ICHS7B) for the identification of only drug-induced long QT and pro-arrhythmias have certain limitations.... 
ventricular fibrillation (VF) | conduction time | INa | ventricular tachycardia (VT) | drug | I | Na | Drug | Conduction time | Ventricular fibrillation (VF) | Ventricular tachycardia (VT) | FIBRILLATION | FLECAINIDE | VENTRICULAR-TACHYCARDIA | MECHANISMS | PROLONGATION | SUDDEN UNEXPECTED DEATH | BRUGADA-SYNDROME | I-Na | LIDOCAINE | ACUTE MYOCARDIAL-INFARCTION | PHARMACOLOGY & PHARMACY | CHANNELS | Lidocaine - pharmacology | Lidocaine - adverse effects | Arrhythmias, Cardiac - chemically induced | Cricetulus | Myocardial Reperfusion Injury - chemically induced | Anti-Arrhythmia Agents - pharmacology | Tachycardia, Ventricular - chemically induced | Electric Conductivity | Sodium Channels - physiology | Purkinje Fibers - drug effects | Sodium Channel Blockers - adverse effects | Ventricular Fibrillation - physiopathology | Ether-A-Go-Go Potassium Channels - physiology | CHO Cells | Drug Evaluation, Preclinical - methods | Rabbits | Cricetinae | Sodium Channel Blockers - pharmacology | Flecainide - pharmacology | Heart Conduction System - drug effects | Myocardial Reperfusion Injury - physiopathology | Flecainide - adverse effects | Patch-Clamp Techniques | Tachycardia, Ventricular - physiopathology | Animals | Anti-Arrhythmia Agents - adverse effects | Ventricular Fibrillation - chemically induced | In Vitro Techniques | Purkinje Fibers - physiology | Sodium | Cardiac arrhythmia | Index Medicus | Research Papers | I Na
Journal Article
Circulation Research, ISSN 0009-7330, 07/2013, Volume 113, Issue 3, pp. 313 - 321
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2013, Volume 304, Issue 4, pp. 600 - 609
Mesenchymal stem cells (MSCs) were shown to improve cell survival and alleviate cardiac arrhythmias when transplanted into cardiac tissue; however, little is... 
Microelectrode array | Connexin 43 | Wnt | Conditioned media | Mesenchymal stem cells | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | MYOCARDIAL-INFARCTION | conditioned media | OVEREXPRESSING AKT | VENTRICULAR MYOCYTES | BETA-CATENIN | microelectrode array | IN-VITRO | REPAIR | CARDIOMYOCYTE | mesenchymal stem cells | PROTEIN-2 SFRP2 | PERIPHERAL VASCULAR DISEASE | connexin 43 | STROMAL CELLS | EXPRESSION | Phosphorylation | Heart Conduction System - enzymology | Wnt Signaling Pathway - physiology | Glycogen Synthase Kinase 3 beta | Myocytes, Cardiac - enzymology | Paracrine Communication - physiology | Lithium Chloride - pharmacology | Heart Conduction System - physiology | Up-Regulation - physiology | Chalcones - pharmacology | Cell Line | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Connexin 43 - biosynthesis | Heart Conduction System - drug effects | Up-Regulation - drug effects | Culture Media, Conditioned | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | Animals | Myocytes, Cardiac - drug effects | Wnt Signaling Pathway - drug effects | Myocytes, Cardiac - physiology | beta Catenin - antagonists & inhibitors | Paracrine Communication - drug effects | Mice | Mesenchymal Stem Cell Transplantation | Physiological aspects | Cell interaction | Research | Health aspects | Stem cells | Heart cells | Molecules | Cardiac arrhythmia | Signal transduction | Index Medicus | Integrative Cardiovascular Physiology and Pathophysiology
Journal Article
Journal of Cardiovascular Electrophysiology, ISSN 1045-3873, 03/2014, Volume 25, Issue 3, pp. 317 - 323
Journal Article
JAMA Internal Medicine, ISSN 2168-6106, 08/2016, Volume 176, Issue 8, pp. 1085 - 1092
Journal Article
Cardiovascular Research, ISSN 0008-6363, 04/2017, Volume 113, Issue 5, pp. 464 - 474
Aims Loss-of-function mutations in SCN5A, the gene encoding NaV1.5 channel, have been associated with inherited progressive cardiac conduction disease (PCCD).... 
Smad2/3 | Connexin 43 | NaV1.5 | GW788388 | CTGF | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | TGF-BETA | FLECAINIDE | CHANNEL GENE SCN5A | HEART FIBROSIS | TARGETED DISRUPTION | MICE | DYSFUNCTION | MUTATIONS | EXPRESSION | Age Factors | Anti-Arrhythmia Agents - pharmacology | Cardiomyopathies - prevention & control | Male | Mice, 129 Strain | Arrhythmias, Cardiac - physiopathology | Cardiomyopathies - genetics | Cardiomyopathies - physiopathology | Female | Benzamides - pharmacology | NAV1.5 Voltage-Gated Sodium Channel - genetics | Arrhythmias, Cardiac - genetics | Disease Models, Animal | Pyrazoles - pharmacology | Arrhythmias, Cardiac - metabolism | Heart Rate | Genetic Predisposition to Disease | Heart Conduction System - metabolism | Connexin 43 - metabolism | Flecainide - pharmacology | Heart Conduction System - drug effects | Mice, Knockout | Arrhythmias, Cardiac - drug therapy | Phenotype | Animals | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Heart Conduction System - physiopathology | Heart Ventricles - physiopathology | Membrane Potentials | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Cardiomyopathies - metabolism | Fibrosis | Voltage-Gated Sodium Channel Blockers - pharmacology | Heterozygote | Heart Ventricles - metabolism | Kinetics | Transforming Growth Factor beta - metabolism | Ventricular Remodeling - drug effects | Heart Ventricles - drug effects | NAV1.5 Voltage-Gated Sodium Channel - deficiency | Index Medicus | Life Sciences
Journal Article