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The New England Journal of Medicine, ISSN 0028-4793, 03/2013, Volume 368, Issue 13, pp. 1210 - 1219
In this trial, patients with systolic heart failure and anemia were assigned to receive either darbepoetin alfa or placebo. At 28 months, there was no... 
MORTALITY | CONTROLLED-TRIAL | CITY CARDIOMYOPATHY QUESTIONNAIRE | EPOETIN | MORBIDITY | REDUCTION | DOUBLE-BLIND | CHRONIC KIDNEY-DISEASE | MEDICINE, GENERAL & INTERNAL | Shock, Septic - etiology | Double-Blind Method | Heart Failure, Systolic - drug therapy | Hematinics - therapeutic use | Erythropoietin - therapeutic use | Heart Failure, Systolic - mortality | Humans | Middle Aged | Kaplan-Meier Estimate | Proportional Hazards Models | Erythropoietin - adverse effects | Hematinics - adverse effects | Male | Thromboembolism - etiology | Erythropoietin - analogs & derivatives | Stroke - etiology | Anemia - drug therapy | Treatment Failure | Female | Aged | Darbepoetin alfa | Anemia - etiology | Hemoglobins - analysis | Heart Failure, Systolic - complications | Heart failure | Usage | Care and treatment | Anemia | Patient outcomes | Diagnosis | Clinical trials | Patient safety | Hemoglobin | Thromboembolism | Patients | Heart diseases | Cancer | Shock | Systolic/mortality | Hematinics/adverse effects | chronic heart failure | Erythropoietin/analogs & derivatives | Thromboembolism/etiology | Klinisk medicin | Heart Failure | Anemia/drug therapy | Hematinics/therapeutic use | Erythropoietin/therapeutic use | Hemoglobins/analysis | Anemia/etiology | Erythropoietin/adverse effects | Stroke/etiology | Clinical Medicine | Systolic/complications | Septic/etiology | Systolic/drug therapy
Journal Article
Circulation, ISSN 0009-7322, 08/2015, Volume 132, Issue 5, pp. 402 - 414
BACKGROUND—Impairment in left ventricular systolic function has been described in heart failure (HF) with preserved ejection fraction (HFpEF), but its... 
clinical trial | strain | heart failure | heart ventricles | spironolactone | preserved left ventricular function | CARDIAC-FUNCTION | CARDIAC & CARDIOVASCULAR SYSTEMS | TOPCAT TRIAL | ALDOSTERONE ANTAGONIST TRIAL | MYOCARDIAL DEFORMATION | RANDOMIZED CONTROLLED-TRIAL | EUROPEAN-SOCIETY | DIASTOLIC DYSFUNCTION | SOCIETY-OF-CARDIOLOGY | SPECKLE TRACKING ECHOCARDIOGRAPHY | PERIPHERAL VASCULAR DISEASE | AMERICAN-SOCIETY | Prognosis | Follow-Up Studies | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Ventricular Dysfunction, Left - mortality | Incidence | Spironolactone - pharmacology | Mineralocorticoid Receptor Antagonists - pharmacology | Aged, 80 and over | Electrocardiography | Female | Spironolactone - therapeutic use | Double-Blind Method | Heart Failure, Systolic - drug therapy | Heart Failure, Systolic - mortality | Heart Arrest - epidemiology | Stroke Volume - physiology | Stroke Volume - drug effects | Survival Rate | Treatment Outcome | Ventricular Dysfunction, Left - physiopathology | Mineralocorticoid Receptor Antagonists - therapeutic use | Ventricular Dysfunction, Left - drug therapy | Internationality | Heart Failure, Systolic - physiopathology | Aged | Heart failure | Usage | Echocardiography | Research | Heart ventricles | Risk factors | Heart failure with preserved ejection fraction | systolic function | clinical trials | echocardiography
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 378, Issue 9792, pp. 676 - 683
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2012, Volume 59, Issue 18, pp. 1598 - 1603
Journal Article
CIRCULATION-HEART FAILURE, ISSN 1941-3289, 01/2011, Volume 4, Issue 1, pp. 8 - 17
Journal Article
European Journal of Heart Failure, ISSN 1388-9842, 2013, Volume 15, Issue 9, pp. 1062 - 1073
Journal Article
Science, ISSN 0036-8075, 3/2011, Volume 331, Issue 6023, pp. 1439 - 1443
Decreased cardiac contractility is a central feature of systolic heart failure. Existing drugs increase cardiac contractility indirectly through signaling... 
Heart | Phosphates |