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The Lancet (British edition), ISSN 0140-6736, 2010, Volume 376, Issue 9744, pp. 886 - 894
Summary Background Raised resting heart rate is a marker of cardiovascular risk. We postulated that heart rate is also a risk factor for cardiovascular events in heart failure... 
Internal Medicine | RATE REDUCTION | HUMAN MYOCARDIUM | MEDICINE, GENERAL & INTERNAL | SYSTOLIC DYSFUNCTION BEAUTIFUL | CARDIOVASCULAR-DISEASE | DOUBLE-BLIND | ATHEROSCLEROSIS | CORONARY-ARTERY-DISEASE | BETA-BLOCKER | IVABRADINE | LEFT-VENTRICULAR FUNCTION | Benzazepines - adverse effects | Humans | Middle Aged | Heart Failure - physiopathology | Male | Sinoatrial Node - drug effects | Heart Rate - drug effects | Electrocardiography | Adult | Female | Heart Failure - mortality | Severity of Illness Index | Heart Failure - complications | Cardiovascular Agents - administration & dosage | Double-Blind Method | Risk Factors | Kaplan-Meier Estimate | Treatment Outcome | Heart Failure - drug therapy | Cardiovascular Agents - therapeutic use | Benzazepines - therapeutic use | Aged | Benzazepines - administration & dosage | Cardiovascular Agents - adverse effects | Chronic Disease | Heart failure | Prevention | Heart beat | Dosage and administration | Drug therapy | Health aspects | Risk factors | Cardiovascular agents | Studies | Heart rate | Cardiovascular disease | Mortality | Cardiovascular diseases | use | Sinoatrial Node/drug effects | Heart Failure/complications/drug therapy/mortality/physiopathology | Kardiologi | Cardiac and Cardiovascular Systems | Benzazepines/administration & dosage/adverse effects/therapeutic use | Heart Rate/drug effects | Cardiovascular Agents/administration & dosage/adverse effects/therapeutic | Kaplan-Meiers Estimate
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2010, Volume 376, Issue 9744, pp. 875 - 885
Journal Article
The Journal of physiology, ISSN 0022-3751, 2011, Volume 589, Issue 14, pp. 3641 - 3658
...: brown adipose tissue (BAT) temperature for non-shivering thermogenesis and arterial pressure and heart rate for cardiovascular responses... 
PHYSIOLOGY | NONSHIVERING THERMOGENESIS | 5-HT1A RECEPTORS | SYMPATHETIC PREMOTOR NEURONS | SPINAL-CORD | DORSOMEDIAL HYPOTHALAMUS | BROWN ADIPOSE-TISSUE | EXPRESSING PREOPTIC NEURONS | BODY-TEMPERATURE | NEUROSCIENCES | PROSTAGLANDIN EP3 RECEPTOR | RAPHE PALLIDUS | Skin Temperature - physiology | Neural Pathways - drug effects | Efferent Pathways - physiology | Fever - metabolism | Male | Preoptic Area - metabolism | Neural Pathways - physiology | Fever - physiopathology | N-Methylaspartate - pharmacology | Neurons - metabolism | Medulla Oblongata - physiology | Preoptic Area - physiology | Dinoprostone - pharmacology | Body Temperature Regulation - physiology | Shivering - physiology | Rats | Mediodorsal Thalamic Nucleus - drug effects | Tachycardia - metabolism | Raphe Nuclei - drug effects | Raphe Nuclei - physiology | Neural Pathways - metabolism | Adipose Tissue, Brown - drug effects | Receptors, GABA-A - metabolism | Muscimol - pharmacology | Rats, Wistar | Preoptic Area - drug effects | Sympathetic Nervous System - drug effects | GABA-A Receptor Antagonists - metabolism | Sympathetic Nervous System - metabolism | Raphe Nuclei - metabolism | Thermogenesis - physiology | Heart Rate - drug effects | Mediodorsal Thalamic Nucleus - metabolism | Sympathetic Nervous System - physiology | Shivering - drug effects | Neurons - physiology | Heart Rate - physiology | Blood Pressure - drug effects | Blood Pressure - physiology | Tachycardia - pathology | Mediodorsal Thalamic Nucleus - physiology | Neurons - drug effects | Receptor, Serotonin, 5-HT1A - metabolism | Cold Temperature | Medulla Oblongata - drug effects | Medulla Oblongata - metabolism | Adipose Tissue, Brown - physiology | 8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology | Efferent Pathways - metabolism | Animals | Thermogenesis - drug effects | GABA | Heart beat | Neurons | Analysis | Prostaglandins E | Heart rate | Skin | Cooling | Thermogenesis | Cold | Rodents | Integrative
Journal Article
Circulation (New York, N.Y.), ISSN 1524-4539, 2015, Volume 132, Issue 18, pp. 1719 - 1725
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47792
Despite increased risk of a recurrent stroke following a minor stroke, information is minimal regarding the interaction between injurious mild cerebral... 
CELLS | OXIDATIVE STRESS | DISEASES | MULTIDISCIPLINARY SCIENCES | INJURY | TRANS-RESVERATROL | RAT-BRAIN | MODEL | ISCHEMIA-REPERFUSION | BLOOD-BRAIN-BARRIER | EXPRESSION | Inflammation - pathology | Recurrence | Stilbenes - administration & dosage | Stilbenes - therapeutic use | Body Temperature - drug effects | Endothelium, Vascular - drug effects | Stilbenes - pharmacology | Stroke - physiopathology | Brain - metabolism | Stroke - pathology | Heart Rate - drug effects | Inflammation - complications | Liver - drug effects | Oxidation-Reduction - drug effects | Blood Pressure - drug effects | Stress, Physiological - drug effects | Cell Death - drug effects | Biomarkers - metabolism | Cell Hypoxia - drug effects | Oxygen | Stroke - prevention & control | Administration, Oral | Cerebrovascular Circulation - drug effects | Liver - metabolism | Blood Gas Analysis | Rats | Treatment Outcome | Stroke - drug therapy | Blood-Brain Barrier - drug effects | Brain - drug effects | Blood-Brain Barrier - pathology | Glucose - deficiency | Animals | Nitrosation - drug effects | Brain - pathology | Endothelium, Vascular - pathology | Stilbenes - blood | Endothelial Cells - pathology | Endothelial Cells - drug effects | Stroke (Disease) | Usage | Care and treatment | Health aspects | Resveratrol | Cell culture | Oxidative stress | Neurosciences | Pressure effects | Glucose | Health physics | Toxicology | Ischemia | Blood-brain barrier | Cerebral blood flow | Temperature effects | Rodents | Gangrene | Physiology | Blood pressure | Inhibition | Drug dosages | Informatics | Edema | Deprivation | Stroke | Body temperature | Health risks | Pharmacology | Inflammation | Chromatography | Endothelial cells | Blood flow | Endothelium | Medicine | Cell death | Nitric oxide | Brain damage | In vivo methods and tests | Brain injury | Apoptosis
Journal Article
Circulation (New York, N.Y.), ISSN 0009-7322, 09/2016, Volume 134, Issue 10, pp. 752 - 772
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2013, Volume 169, Issue 5, pp. 1048 - 1057
.... Dipeptidyl peptidase‐4 (DPP‐4) inhibitors, vildagliptin and sitagliptin, are oral anti‐diabetic drugs often prescribed in patients with cardiovascular disease... 
high‐fat diet | cardiac function | sitagliptin | vildagliptin | insulin resistance | high-fat diet | SURVIVAL | MODEL | LIPOPROTEIN | INFARCTION | IV INHIBITOR SITAGLIPTIN | DPP-4 INHIBITION | GLUCAGON-LIKE PEPTIDE-1 | IMPROVES | PHARMACOLOGY & PHARMACY | DYSFUNCTION | Body Weight | Reactive Oxygen Species - metabolism | Nitriles - pharmacology | Obesity - drug therapy | Rats, Wistar | Cholesterol - blood | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Heart - physiology | Diet, High-Fat - adverse effects | Male | Pyrazines - therapeutic use | Mitochondria, Heart - drug effects | Insulin - blood | Membrane Potential, Mitochondrial - drug effects | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Pyrrolidines - pharmacology | Pyrrolidines - therapeutic use | Cardiotonic Agents - therapeutic use | Heart Rate - drug effects | Malondialdehyde - blood | Adamantane - therapeutic use | Blood Pressure - drug effects | Sitagliptin Phosphate | Adamantane - analogs & derivatives | Triazoles - therapeutic use | Malondialdehyde - metabolism | Adamantane - pharmacology | Blood Glucose - analysis | Insulin Resistance | Obesity - physiopathology | Cardiotonic Agents - pharmacology | Obesity - metabolism | Triazoles - pharmacology | Animals | Mitochondria, Heart - physiology | Heart - drug effects | Oxidative Stress - drug effects | Pyrazines - pharmacology | Nitriles - therapeutic use | Heart | Obesity | Heart beat | Body weight | Insulin resistance | Insulin | Cholesterol | Research Papers
Journal Article
British journal of pharmacology, ISSN 0007-1188, 2012, Volume 167, Issue 5, pp. 1035 - 1047
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 8, p. e104020
Hypertension is considered as a low-grade inflammatory disease, with adaptive immunity being an important mediator of this pathology. TLR4 may have a role in... 
OXIDATIVE STRESS | ACTIVATION | IMMUNE-SYSTEM | ENDOTHELIAL DYSFUNCTION | RESISTANCE ARTERIES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | LIPOPOLYSACCHARIDE | SMOOTH-MUSCLE-CELLS | EXPRESSION | BLOOD-PRESSURE | Reactive Oxygen Species - metabolism | Rats, Wistar | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Male | Heart Rate - drug effects | Phenylephrine - pharmacology | Superoxides - metabolism | Blood Pressure - drug effects | Aorta - physiopathology | Hypertension - genetics | Toll-Like Receptor 4 - antagonists & inhibitors | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Rats, Inbred SHR | Angiotensin II - pharmacology | Acetylcholine - pharmacology | Aorta - drug effects | Endothelium, Vascular - physiopathology | Toll-Like Receptor 4 - genetics | Antioxidants - pharmacology | Toll-Like Receptor 4 - metabolism | Vasoconstriction - drug effects | Hypertension - pathology | Hypertension - physiopathology | Aorta - pathology | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Cell Movement - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Endothelium, Vascular - pathology | Cell Proliferation - drug effects | Oxidative Stress - drug effects | Vasodilation - drug effects | In Vitro Techniques | Potentiation | Oxidative stress | Reactive oxygen species | Biomedical research | Immunoglobulin G | Smooth muscle | Innate immunity | mRNA | Activation | Biochemistry | Immunity | Experiments | Contraction | NAD(P)H oxidase | Ethics | Renin | Catalase | Rodents | Atherosclerosis | Phenylephrine | Toll-like receptors | Aorta | Physiology | Blood pressure | Angiotensin II | Heart diseases | Hypertension | Heparan sulfate | Oxygen | Muscles | Rats | Superoxide | Inflammation | Adaptive immunity | TLR4 protein | Yang, Cindy | Endothelium | Heart rate | NAD | Pathology | Angiotensin | Acetylcholine | Cardiovascular diseases
Journal Article