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Lancet Neurology, The, ISSN 1474-4422, 2007, Volume 6, Issue 9, pp. 826 - 829
Summary Background Retroperitoneal and pleuropulmonary fibrosis are well known but rare complications of the treatment of Parkinson's disease with ergolinic... 
Neurology | FIBROSIS | DRUG | PERGOLIDE | REGURGITATION | CABERGOLINE | CARDIAC VALVULOPATHY | FENFLURAMINE | 5-HT2B RECEPTORS | CLINICAL NEUROLOGY | Heart Valve Diseases - chemically induced | Dopamine Agonists - adverse effects | Parkinson Disease - drug therapy | Ergolines - adverse effects | Pergolide - adverse effects | Humans | Drug therapy | Parkinson's disease
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/1997, Volume 337, Issue 9, pp. 581 - 588
Journal Article
Journal Article
Journal Article
Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9689, pp. 577 - 585
Summary The initial association between the development of valvular heart disease and drugs stems from observations made during the use of methysergide and... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | OBESE-PATIENTS | ERGOTAMINE THERAPY | CARDIAC VALVULOPATHY | TRICUSPID REGURGITATION | AORTIC REGURGITATION | MIGRAINE HEADACHE | VALVE DISEASE | DOPAMINE AGONISTS | PARKINSONS-DISEASE | WEIGHT CONTROL | Methysergide - adverse effects | Appetite Depressants - adverse effects | Vasoconstrictor Agents - adverse effects | Humans | N-Methyl-3,4-methylenedioxyamphetamine - adverse effects | Receptors, Serotonin - drug effects | Dexfenfluramine - adverse effects | Dopamine Agonists - adverse effects | Fenfluramine - adverse effects | Ergolines - adverse effects | Pergolide - adverse effects | Antiparkinson Agents - adverse effects | Migraine Disorders - drug therapy | Serotonin Agents - adverse effects | Heart Valves - pathology | Patient Selection | Serotonin Plasma Membrane Transport Proteins - drug effects | Ergotamine - adverse effects | Fibrosis | Heart Valve Diseases - chemically induced | Heart Valve Diseases - diagnosis | Drug Monitoring | Complications and side effects | Heart valve diseases | Care and treatment | Serotoninergic mechanisms | Appetite depressants | Research | Health aspects | Risk factors | Research methodology | Migraine | Parkinsons disease | Valves | Clinical medicine | Drug therapy | Kinases | Gene expression | Medical disorders | Patients | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 10, pp. 3780 - 3792
The most frequently used oral anti-coagulant warfarin has been implicated in inducing calcification of aortic valve interstitial cells (AVICs), whereas the... 
STEM-CELLS | INDUCED VASCULAR CALCIFICATION | HEART-VALVES | MATRIX GLA-PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | OSTEOBLAST MATURATION | DIFFERENTIATION | EXPRESSION | SKELETAL DEVELOPMENT | RUNX2 | Heart Valve Diseases - pathology | Tumor Suppressor Protein p53 - antagonists & inhibitors | Vitamin K 1 - adverse effects | Humans | Aortic Valve - drug effects | Warfarin - adverse effects | Male | Antifibrinolytic Agents - adverse effects | Calcinosis - chemically induced | Promoter Regions, Genetic - drug effects | Tumor Suppressor Protein p53 - genetics | Aortic Valve - pathology | Snail Family Transcription Factors - agonists | Snail Family Transcription Factors - genetics | RNA Interference | Heart Valve Diseases - chemically induced | Snail Family Transcription Factors - antagonists & inhibitors | Epigenesis, Genetic - drug effects | Calcinosis - metabolism | Disease Models, Animal | Recombinant Proteins - metabolism | Atrial Fibrillation - pathology | Snail Family Transcription Factors - metabolism | Rheumatic Heart Disease - metabolism | Mice, Inbred C57BL | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Recombinant Proteins - chemistry | Anticoagulants - adverse effects | Rheumatic Heart Disease - pathology | Aortic Valve - metabolism | Gene Expression Regulation - drug effects | Atrial Fibrillation - metabolism | Animals | Heart Valve Diseases - metabolism | Genes, Reporter - drug effects | Calcinosis - pathology | Sus scrofa | cardiovascular disease | transcription regulation | aortic valve interstitial cell | apoptosis | calcification | Cell Biology | p53 | warfarin
Journal Article
Pharmacoepidemiology and Drug Safety, ISSN 1053-8569, 12/2010, Volume 19, Issue 12, pp. 1256 - 1262
Purpose To evaluate and quantify in diabetic patients treated with benfluorex in France, a fenfluramine‐derivated product, a possible increase in risk of... 
benfluorex | adverse effects | valvular heart disease | health insurance system | reimbursement databases | pharmacoepidemiology | Pharmacoepidemiology | Valvular heart disease | Reimbursement databases | Adverse effects | Benfluorex | Health insurance system | APPETITE-SUPPRESSANT DRUGS | DATABASES | RISK | 5-HT2B RECEPTORS | FRANCE | PHARMACOLOGY & PHARMACY | PATIENT | FENFLURAMINE | Appetite Depressants - adverse effects | Heart Valve Diseases - pathology | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Risk | Appetite Depressants - therapeutic use | Mitral Valve Insufficiency - epidemiology | Medical Record Linkage - methods | Pharmacoepidemiology - methods | Heart Valve Diseases - epidemiology | Aortic Valve Insufficiency - chemically induced | Heart Valve Diseases - chemically induced | Adult | Female | Databases, Factual | Fenfluramine - therapeutic use | Mitral Valve Insufficiency - chemically induced | France - epidemiology | Fenfluramine - analogs & derivatives | Diabetes Mellitus - drug therapy | Fenfluramine - adverse effects | Heart Valve Prosthesis Implantation - statistics & numerical data | Aged | Aortic Valve Insufficiency - epidemiology | Cohort Studies | Side effects | Historical account | Diabetes mellitus | Insurance | Surgery | Gender | Cardiovascular diseases | Heart diseases | Age
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2010, Volume 56, Issue 21, pp. 1752 - 1759
Journal Article
Circulation, ISSN 0009-7322, 03/2005, Volume 111, Issue 12, pp. 1517 - 1522
Journal Article