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COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, ISSN 1943-0264, 04/2019, Volume 11, Issue 4
Heat shock factors (HSFs) are the main transcriptional regulators of the heat shock response and indispensable for maintaining cellular proteostasis. HSFs... 
MOUSE TESTIS | YEAST | DNA-BINDING DOMAIN | TARGETED DISRUPTION | ACTIVATION | Y-CHROMOSOME | TRANSCRIPTION FACTOR HSF1 | STRESS-RESPONSE | GENE-EXPRESSION | CELL-CYCLE | CELL BIOLOGY | Regulators | Cell survival | Transcription | Genes | Genetic diversity | Chaperones | Cellular stress response | Heat shock factors | Heat shock | Genetic programs
Journal Article
The FEBS Journal, ISSN 1742-464X, 06/2017, Volume 284, Issue 11, pp. 1606 - 1627
Living organisms are endowed with the capability to tackle various forms of cellular stress due to the presence of molecular chaperone machinery complexes that... 
HSF1 inhibitor | HSF1 activator | cytoprotection | hormesis | sulfhydryl reactivity | phytochemical | DNA-BINDING DOMAIN | TRANSCRIPTION FACTOR HSF1 | CELLULAR STRESS-RESPONSE | MOLECULAR CHAPERONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | INTERACTING PROTEIN 1-LIKE | FACTOR-I | DIFFERENTIAL REGULATION | INDUCED UP-REGULATION | Mammals - genetics | Phosphorylation | Transcription Factors - chemistry | Phylogeny | Heat Shock Transcription Factors | DNA-Binding Proteins - agonists | Adaptation, Physiological - genetics | Mammals - physiology | Transcription, Genetic | Acetylation | Stress, Physiological - physiology | DNA-Binding Proteins - physiology | Transcription Factors - physiology | DNA-Binding Proteins - antagonists & inhibitors | Stress, Physiological - genetics | Gene Expression Regulation | Adaptation, Physiological - physiology | Models, Molecular | Transcription Factors - antagonists & inhibitors | Hot Temperature | DNA-Binding Proteins - chemistry | Protein Folding | Animals | Sumoylation | Protein Conformation | Protein Processing, Post-Translational | Proteasome Endopeptidase Complex - metabolism | Transcription Factors - agonists | Heat shock proteins | Physiological aspects | Chromatin | Molecular structure | Genes | Cytology | Homeostasis | Agglomeration | Heat shock factors | Machinery and equipment | Degradation | Proteins | SUMO protein | Elevation | Control | Protein folding | Post-translation | HSF1 protein | Repair | Stresses | Translation | Macromolecules | Maintenance | Mammals | Metabolism | Stress | Heat | Inhibitors | Structural damage | Proteasomes | Cellular structure | Heat shock | Structure-function relationships
Journal Article
Archives of Toxicology, ISSN 0340-5761, 1/2013, Volume 87, Issue 1, pp. 19 - 48
Heat shock proteins (HSP) are a subset of the molecular chaperones, best known for their rapid and abundant induction by stress. HSP genes are activated at the... 
Environmental Health | Prognosis | Heat shock proteins | Heat shock factor | Metastasis | Drug resistance | Carcinogenesis | Biomedicine general | Biomedicine | Occupational Medicine/Industrial Medicine | Pharmacology/Toxicology | Cancer | Apoptosis | TRANSCRIPTION FACTOR HSF1 | ALPHA-B-CRYSTALLIN | C-DEPENDENT ACTIVATION | NEGATIVE REGULATOR | CISPLATIN-INDUCED APOPTOSIS | BREAST-CANCER CELLS | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | TOXICOLOGY | HEAT-SHOCK-PROTEIN-70 HSP70 | SMALL STRESS-PROTEINS | Neoplasms - metabolism | Molecular Chaperones - metabolism | Epigenesis, Genetic | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Heat Shock Transcription Factors | DNA-Binding Proteins - metabolism | Neoplasms - genetics | Neoplastic Stem Cells - metabolism | Tumor Suppressor Proteins - genetics | Neoplastic Stem Cells - pathology | Neoplasms - radiotherapy | Chaperonin 60 - metabolism | HSP90 Heat-Shock Proteins - genetics | Chaperonin 60 - genetics | Tumor Suppressor Proteins - metabolism | Signal Transduction | Molecular Chaperones - genetics | HSP70 Heat-Shock Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | HSP70 Heat-Shock Proteins - metabolism | Neoplasms - drug therapy | Transcription Factors - metabolism | HSP90 Heat-Shock Proteins - metabolism | Heat-Shock Proteins - physiology | Neoplasms - pathology | Proteins | Care and treatment | Nuclear radiation | Development and progression | Genetic transcription | Tumors | Carcinogens | Index Medicus | carcinogenesis | metastasis | apoptosis | cancer | drug resistance | heat shock factor | prognosis
Journal Article