X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
hec1 (77) 77
index medicus (55) 55
humans (49) 49
cell biology (37) 37
nuclear proteins - metabolism (35) 35
kinetochores - metabolism (34) 34
biochemistry & molecular biology (33) 33
mitosis (33) 33
microtubules - metabolism (28) 28
nuclear proteins - genetics (27) 27
animals (24) 24
chromosomes (24) 24
kinetochore (23) 23
ndc80 (22) 22
ndc80 complex (22) 22
chromosome segregation (20) 20
cancer (18) 18
kinetochores (18) 18
protein (18) 18
hela cells (17) 17
research (17) 17
complex (16) 16
nuclear proteins - chemistry (16) 16
proteins (16) 16
cell cycle (15) 15
cell line, tumor (15) 15
microtubule attachment (15) 15
cell division (14) 14
spindle checkpoint (14) 14
apoptosis (13) 13
article (13) 13
phosphorylation (13) 13
protein binding (13) 13
protein-serine-threonine kinases - metabolism (13) 13
spindle apparatus - metabolism (13) 13
centromere (12) 12
kinetochores - chemistry (12) 12
microtubules (12) 12
budding yeast (11) 11
cell cycle proteins - metabolism (11) 11
checkpoint (11) 11
female (11) 11
mice (11) 11
attachment (10) 10
cell cycle proteins - genetics (10) 10
genetics & heredity (10) 10
kinetochore-microtubule attachment (10) 10
mitotic checkpoint (10) 10
mitotic spindle (10) 10
molecular architecture (10) 10
nuf2 (10) 10
oncology (10) 10
spindle assembly checkpoint (10) 10
aneuploidy (9) 9
architecture (9) 9
binding (9) 9
in-vivo (9) 9
microtubule (9) 9
models, molecular (9) 9
mutation (9) 9
nuclear proteins - antagonists & inhibitors (9) 9
outer kinetochore (9) 9
rna interference (9) 9
saccharomyces cerevisiae proteins - metabolism (9) 9
analysis (8) 8
aurora kinases (8) 8
binding sites (8) 8
cells (8) 8
chromosomal proteins, non-histone - metabolism (8) 8
genetic aspects (8) 8
growth (8) 8
microtubule-associated proteins - metabolism (8) 8
models, biological (8) 8
amino acid sequence (7) 7
male (7) 7
microscopy, fluorescence (7) 7
microtubules - chemistry (7) 7
nima-related kinases (7) 7
physiological aspects (7) 7
protein conformation (7) 7
saccharomyces cerevisiae proteins - chemistry (7) 7
ska complex (7) 7
spindle (7) 7
aurora-b (6) 6
components (6) 6
dynamics (6) 6
expression (6) 6
kinase (6) 6
mammalian-cells (6) 6
metaphase (6) 6
microscopy (6) 6
molecular biology (6) 6
molecular sequence data (6) 6
protein structure, tertiary (6) 6
recruitment (6) 6
xenograft model antitumor assays (6) 6
antineoplastic agents - pharmacology (5) 5
aurora kinase b (5) 5
biophysics (5) 5
care and treatment (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Science, ISSN 0036-8075, 06/2015, Volume 348, Issue 6240, pp. 1260 - 1264
The spindle checkpoint of the cell division cycle senses kinetochores that are not attached to microtubules and prevents precocious onset of anaphase, which... 
LOCALIZATION | RECRUITMENT | PROTEIN | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | SPINDLE ASSEMBLY CHECKPOINT | HEC1 | KINASE MPS1 | BUB1 | AURORA-B | REVEALS | Proteins | Cell division | Microbiology | Molecular biology | Kinases | Binding | Attachment | Spindles | Chromosomes | Recruitment
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 11/2019, Volume 218, Issue 11, pp. 3583 - 3596
The spindle assembly checkpoint (SAC) prevents anaphase until all kinetochores attach to the spindle. Each mammalian kinetochore binds many microtubules, but... 
MITOSIS | RECRUITMENT | COMPLEX | MPS1 | PHOSPHORYLATION | CHROMOSOME CONGRESSION | DYNAMICS | SPINDLE ASSEMBLY CHECKPOINT | HEC1 | POLE | CELL BIOLOGY | Binding | Change detection | Kinetochores | Microtubules | Information processing | Occupancy | Laser ablation | Mammals | Ablation | Anaphase
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2019, Volume 294, Issue 2, pp. 576 - 592
Faithful chromosome segregation during mitosis is critical for maintaining genome integrity in cell progeny and relies on accurate and robust... 
ACTIVATION | spindle assembly | PHOSPHORYLATION | MPS1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | HEC1 | mitosis | IDENTIFICATION | chromosomal segregation | microtubule | protein acylation | NUF2 | TIP60 | kinetochore | ARCHITECTURE | SKA COMPLEX | NDC80 complex | BINDING | mitotic spindle | AURORA-B | Index Medicus
Journal Article
Cell Division, ISSN 1747-1028, 10/2016, Volume 11, Issue 1, p. 14
Background: Recent experiments regarding Ndc80/Hec1 in force generation at kinetochores for chromosome motions have prompted speculation about possible models... 
Chromosome | Motility | Ndc80/Hec1 | Mitosis | Electrostatics | COMPLEX | SPINDLE MICROTUBULES | MECHANISM | BEHAVIOR | INTRACELLULAR PH | CELL BIOLOGY | IN-VITRO | CALCIUM | MICROTUBULE ATTACHMENT | GENERATION
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 16, pp. 5755 - 5765
Chromosome alignment and segregation during mitosis require kinetochore-microtubule (kMT) attachments that are mediated by the molecular motor dynein and the... 
CYTOPLASMIC DYNEIN | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CONGRESSION | MITOTIC SPINDLE | CENP-E | CHROMOSOME ALIGNMENT | SPINDLE ASSEMBLY CHECKPOINT | HEC1 | MECHANISMS | POLEWARD | Rod | chromosomes | Hec1 | mitosis | Cell Biology | microtubule | dynein | kinetochore | alignment | segregation | checkpoint control | mitotic spindle | Ndc80
Journal Article
Current Biology, ISSN 0960-9822, 06/2017, Volume 27, Issue 11, pp. 1692 - 1699.e3
The kinetochore links chromosomes to dynamic spindle microtubules and drives both chromosome congression and segregation. To do so, the kinetochore must hold... 
microtubule | kinetochore | Hec1 | mechanics | force generation | mitosis | spindle | kinetochore-microtubule interface | friction | Ndc80 | NDC80 COMPLEX | ANAPHASE | ATTACHMENT | FORCE GENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CENTROMERE STRETCH | MITOTIC SPINDLE | DYNAMICS | TENSION | CHROMOSOME SEGREGATION | DIRECTIONAL INSTABILITY | CELL BIOLOGY | Chromosomes | Cells | Polymerization | Mitosis
Journal Article