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Journal Article
ACS chemical biology, ISSN 1554-8929, 08/2014, Volume 9, Issue 8, pp. 1747 - 1754
.... While helical protein–protein interactions have been heavily targeted, a similar level of success for the inhibition of β-strand and β... 
MULTIPROTEIN COMPLEXES | GRB2 SH2 DOMAIN | SHEET FORMATION | DESIGN | ALPHA-HELIX | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRYSTAL-STRUCTURES | HOT-SPOTS | SECONDARY STRUCTURE | HIGH-HANGING FRUIT | Models, Molecular | Protein Binding | Proteins - chemistry | Protein Structure, Secondary
Journal Article
Nucleic acids research, ISSN 0305-1048, 12/2010, Volume 38, Issue 22, pp. 8306 - 8315
... with roles in target binding. Analysis of the aptamer consensus sequences suggested that the conserved segments could form duplexes via Watson-Crick base-pairing with preferred sequences in one strand of the DNA... 
PEPTIDE NUCLEIC-ACIDS | INVASION | LONG TERMINAL REPEAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | SEQUENCE | TRANSCRIPTION | GENE-EXPRESSION | POLYMERASE | HELIX | SECONDARY STRUCTURE | TRIPLEX-FORMING OLIGONUCLEOTIDES | Consensus Sequence | DNA, Viral - chemistry | SELEX Aptamer Technique | Base Sequence | Cloning, Molecular | Aptamers, Nucleotide - chemistry | HIV Long Terminal Repeat | HIV-1 - genetics | RNA - chemistry | Binding Sites | RNA
Journal Article
Journal Article
Nucleic acids research, ISSN 1362-4962, 2007, Volume 35, Issue 15, pp. 5223 - 5231
We performed numerical simulations of DNA chains to understand how local geometry of juxtaposed segments in knotted DNA molecules can guide type II DNA topoisomerases to perform very efficient relaxation of DNA knots... 
TOPOLOGY | ATP HYDROLYSIS | REPLICATION | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | CUBIC LATTICE | JUXTAPOSITION GEOMETRY | STRAND PASSAGE | DOUBLE HELIX | SUPERCOILED DNA | KNOTS | Models, Molecular | DNA Topoisomerases, Type II - metabolism | DNA - chemistry | Nucleic Acid Conformation | Computer Simulation | Structural Biology
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 09/2011, Volume 50, Issue 37, pp. 8735 - 8738
Journal Article
Proteins, structure, function, and bioinformatics, ISSN 0887-3585, 05/2003, Volume 51, Issue 2, pp. 167 - 171
... the possibility of organizing structures containing α‐helices and β‐strands using backbone CH…O interactions, in order to achieve appropriate registry. This approach permits... 
CH…O hydrogen bonds | helix termination | polypeptide folds | αβ motifs | HYDROGEN-BOND | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLOBULAR-PROTEINS | LESSONS | FOLDS | REVERSAL | BIOPHYSICS | C-H...O hydrogen bonds | alpha beta motifs | REVEALS
Journal Article