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Infection and Immunity, ISSN 0019-9567, 2017, Volume 85, Issue 11
Alcohol abuse impairs immune defense. To study the effect of chronicplus-binge alcohol exposure on the granulopoietic response, acute alcohol intoxication... 
Alcohol | Granulopoietic response | Granulocytes | Bacteremia | Cell signaling | Stem cells | granulocytes | PROGENITOR CELLS | MORTALITY | stem cells | INFECTIOUS DISEASES | ESCHERICHIA-COLI BACTEREMIA | BONE-MARROW | granulopoietic response | NEUTROPHILS | IMMUNOLOGY | STEM | DEPENDENCE | LIVER-INJURY | cell signaling | INFECTION | EXPRESSION | bacteremia | Bacteremia - immunology | Binge Drinking - pathology | Male | Proto-Oncogene Proteins c-kit - immunology | Hematopoiesis - drug effects | Escherichia coli Infections - genetics | Nucleotidyltransferases - deficiency | Bone Marrow Cells - immunology | Mitogen-Activated Protein Kinase 1 - genetics | Granulocytes - pathology | Disease Models, Animal | Mitogen-Activated Protein Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Membrane Proteins - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Bone Marrow Cells - pathology | Toll-Like Receptor 4 - genetics | Hematopoiesis - genetics | Toll-Like Receptor 4 - immunology | Hematopoiesis - immunology | Cyclin D1 - immunology | Cyclin D1 - genetics | Escherichia coli Infections - pathology | Signal Transduction - drug effects | CCAAT-Enhancer-Binding Protein-beta - immunology | Escherichia coli Infections - immunology | Mice | Mice, Inbred BALB C | Bacteremia - pathology | Antigens, Ly - genetics | Binge Drinking - immunology | Signal Transduction - immunology | Granulocytes - drug effects | Bone Marrow Cells - drug effects | Proto-Oncogene Proteins c-kit - genetics | Escherichia coli - growth & development | Mitogen-Activated Protein Kinase 3 - immunology | Gene Expression Regulation - immunology | Escherichia coli - immunology | Membrane Proteins - immunology | Bacteremia - genetics | Binge Drinking - genetics | Gene Expression Regulation - drug effects | Ethanol - pharmacology | Animals | Antigens, Ly - immunology | Nucleotidyltransferases - genetics | Nucleotidyltransferases - immunology | Granulocytes - immunology | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 4, pp. 497 - 512
Splenic myelopoiesis provides a steady flow of leukocytes to inflamed tissues, and leukocytosis correlates with cardiovascular mortality. Yet regulation of... 
ATHEROSCLEROTIC LESIONS | PROGENITOR CELLS | TISSUE MACROPHAGE | MEDICINE, RESEARCH & EXPERIMENTAL | COLONY-STIMULATING FACTOR | MARGINAL ZONE | BONE-MARROW | ACUTE MYOCARDIAL-INFARCTION | GENE-EXPRESSION | MONOCYTE SUBSETS | IMMUNOLOGY | LIPID-LIKE MATERIALS
Journal Article
Journal Article
Nature Reviews Clinical Oncology, ISSN 1759-4774, 07/2016, Volume 13, Issue 7, pp. 431 - 446
Around 15 years ago, imatinib mesylate (Gleevec (R) or Glivec (R), Novartis, Switzerland) became the very first 'targeted' anticancer drug to be clinically... 
CHRONIC MYELOGENOUS LEUKEMIA | CYTOTOXIC T-CELLS | KILLER DENDRITIC CELLS | ONCOLOGY | MINOR HISTOCOMPATIBILITY ANTIGENS | HEMATOPOIETIC STEM-CELLS | ACUTE LYMPHOBLASTIC-LEUKEMIA | TYROSINE KINASE INHIBITOR | GASTROINTESTINAL STROMAL TUMORS | COMPLETE MOLECULAR RESPONSE | CHRONIC MYELOID-LEUKEMIA | Tumor Escape - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Antineoplastic Agents - therapeutic use | B7 Antigens - immunology | Drug Approval | Protein-Tyrosine Kinases - immunology | Hematopoiesis - drug effects | Natural Cytotoxicity Triggering Receptor 3 - drug effects | Imatinib Mesylate - therapeutic use | Immunity, Cellular - drug effects | Immune Tolerance - immunology | T-Lymphocytes - drug effects | Protein-Tyrosine Kinases - drug effects | Killer Cells, Natural - immunology | Molecular Chaperones - drug effects | Natural Cytotoxicity Triggering Receptor 3 - immunology | Vascular Endothelial Growth Factor A - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - immunology | Molecular Chaperones - immunology | Molecular Targeted Therapy - methods | Gastrointestinal Stromal Tumors - immunology | Immune Tolerance - drug effects | Tumor Escape - immunology | Antigens, Neoplasm - immunology | Antineoplastic Agents - immunology | B7 Antigens - drug effects | Vascular Endothelial Growth Factor A - immunology | Immunologic Surveillance - drug effects | Forecasting | Immunologic Surveillance - immunology | Hematopoiesis - immunology | Imatinib Mesylate - immunology | Gastrointestinal Stromal Tumors - drug therapy | T-Lymphocytes - immunology | Killer Cells, Natural - drug effects | Antigens, Neoplasm - drug effects | Tyrosine | Care and treatment | Analysis | Immunotherapy | B cells | Drug approval | Cancer
Journal Article