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Journal Article
Circulation Research, ISSN 0009-7330, 04/2012, Volume 110, Issue 9, pp. 1217 - 1225
RATIONALE:The function of Nox4, a source of vascular H2O2, is unknown. Other Nox proteins were identified as mediators of endothelial dysfunction. OBJECTIVE:We... 
Hypertension | Angiogenesis | Carbon monoxide | Nitric oxide | Redox regulation | INDUCED ACTIVATION | nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | redox regulation | angiogenesis | carbon monoxide | ANGIOTENSIN-II | BLOOD-PRESSURE | NAD(P)H OXIDASE | ENDOTHELIAL-CELLS | IN-VIVO | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HYDROGEN-PEROXIDE | HEMATOLOGY | hypertension | UP-REGULATION | Catalase - pharmacology | Heme Oxygenase-1 - metabolism | Humans | NADPH Oxidases - metabolism | Male | Ischemia - genetics | Carbonates - pharmacology | RNA, Messenger - metabolism | NADPH Oxidases - deficiency | Time Factors | NADPH Oxidases - genetics | Carbonates - metabolism | Hemin - pharmacology | Hypertension - enzymology | Hypertension - genetics | Ischemia - pathology | Cytoprotection | Disease Models, Animal | Muscle, Skeletal - blood supply | NADH, NADPH Oxidoreductases - genetics | Hypertension - pathology | Hydrogen Peroxide - metabolism | Mice, Knockout | Human Umbilical Vein Endothelial Cells - enzymology | Organometallic Compounds - metabolism | Mice | Oxidative Stress - drug effects | Endothelial Cells - pathology | Endothelial Cells - enzymology | Hypertrophy | Ischemia - enzymology | Boranes - metabolism | Transfection | NADH, NADPH Oxidoreductases - deficiency | Hypertension - chemically induced | NF-E2-Related Factor 2 - genetics | Membrane Proteins - metabolism | Nitric Oxide Synthase Type III - metabolism | Angiotensin II | Polyethylene Glycols - pharmacology | Carbon Dioxide - metabolism | Mice, Inbred C57BL | Cells, Cultured | Boranes - pharmacology | Antioxidants - pharmacology | Ischemia - physiopathology | NADPH Oxidase 4 | Hypertension - physiopathology | NADPH Oxidase 1 | Animals | Lung - blood supply | Neovascularization, Physiologic | Organometallic Compounds - pharmacology | Apoptosis | Endothelial Cells - drug effects
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e95079 - e95079
We investigated the effect of chronic nicotine on cholinergically-mediated renal vasodilations in female rats and its modulation by the nitric oxide synthase... 
CIGARETTE SMOKERS | CARBON-MONOXIDE | FEMALE RATS | NITRIC-OXIDE SYNTHASE | HEME OXYGENASE-1 INDUCTION | MULTIDISCIPLINARY SCIENCES | ETHANOL | ZINC-PROTOPORPHYRIN | INDUCED IMPAIRMENT | KIDNEY | ENDOTHELIAL FUNCTION | Kidney - blood supply | Rats, Wistar | Area Under Curve | Adenosine-5'-(N-ethylcarboxamide) - pharmacology | Medroxyprogesterone Acetate - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Nicotine - pharmacology | Phenylephrine - pharmacology | Female | Hemin - pharmacology | Heme Oxygenase (Decyclizing) - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Estradiol - pharmacology | Hormones - pharmacology | Kidney - drug effects | Acetylcholine - pharmacology | Papaverine - pharmacology | Enzyme Activation - drug effects | Animals | Signal Transduction - drug effects | Arginine - pharmacology | Nitric Oxide Synthase - metabolism | Vasodilation - drug effects | In Vitro Techniques | Mifepristone - pharmacology | Blood vessels | Acetylcholine | Dilatation | Health aspects | Vasodilators | Transplants & implants | Estrogens | Menopause | AKT protein | Hormones | Vasodilation | Toxicology | Protoporphyrin | Rodents | Modulation | Heme | Phenylephrine | Carbon monoxide | Supplementation | Adenosine | Kidneys | Ovariectomy | Rats | Pharmacology | Nitric-oxide synthase | Zinc | 1-Phosphatidylinositol 3-kinase | NG-Nitroarginine methyl ester | Abdomen | Augmentation | Oxygenase | Medroxyprogesterone acetate | Nitric oxide | Pharmacy | Coronary vessels | Acetic acid | Nicotine | Veins & arteries | Index Medicus
Journal Article
Glia, ISSN 0894-1491, 11/2010, Volume 58, Issue 15, pp. 1858 - 1870
Intracerebral hemorrhage (ICH) induces neurovascular injury via poorly defined mechanisms. The aim of this study was to determine whether gliovascular... 
neurovascular | blood‐brain barrier | glia | GSH | anti‐oxidant | Neurovascular | Blood-brain barrier | Glia | Anti-oxidant | blood-brain barrier | OXIDATIVE STRESS | WHITE-MATTER | anti-oxidant | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | EXPERIMENTAL INTRACEREBRAL HEMORRHAGE | VASCULAR INJURY | ENDOTHELIAL-CELLS | SUBARACHNOID HEMORRHAGE | NITRIC-OXIDE | INFLAMMATORY RESPONSE | EXTRACELLULAR-SUPEROXIDE DISMUTASE | L-Lactate Dehydrogenase - metabolism | Apoptosis - drug effects | Glutathione - metabolism | Humans | Caspase 3 - metabolism | Dose-Response Relationship, Drug | Glutathione - pharmacology | Neuroprotective Agents - pharmacology | Time Factors | Amino Acid Chloromethyl Ketones - pharmacology | Astrocytes - chemistry | Hemin - pharmacology | Microvessels - cytology | Brain - cytology | Cells, Cultured | Curcumin - pharmacology | Enzyme Inhibitors - pharmacology | Antioxidants - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Animals | Peroxynitrous Acid - pharmacology | Acetylcysteine - pharmacology | Ascorbic Acid - pharmacology | Mice | Poly (ADP-Ribose) Polymerase-1 | Nitric Oxide Synthase Type II - metabolism | Peroxynitrite | Catalysts | Astrocytes | Acetylcysteine | Data processing | Gene expression | Caspase-3 | Hemorrhage | Endothelial cells | Nitric-oxide synthase | Antioxidants | Hemin | Hemoglobin | Microvasculature | nitrotyrosine | Injuries | Apoptosis | Communication | Glutathione
Journal Article
Plant Cell Reports, ISSN 0721-7714, 6/2012, Volume 31, Issue 6, pp. 1085 - 1091
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 02/2002, Volume 90, Issue 2, pp. e17 - e24
Carbon monoxide (CO) is generated in living organisms during the degradation of heme by the enzyme heme oxygenase, which exists in constitutive (HO-2 and HO-3)... 
vascular function | CARDIAC & CARDIOVASCULAR SYSTEMS | PROTECTION | carbon monoxide | heme oxygenase-1 | transition metal carbonyls | IRON CARBONYLS | ENDOGENOUS MODULATOR | METAL-METAL BOND | NITRIC-OXIDE | PHOTOCHEMISTRY | PERIPHERAL VASCULAR DISEASE | LIGAND | HEMATOLOGY | DERIVATIVES | EXPRESSION | gene expression | Transition Elements - chemistry | Muscle, Smooth, Vascular - metabolism | Heart - physiology | Protoporphyrins - pharmacology | Vasomotor System - drug effects | Male | Carbon Monoxide - chemistry | Carbon Monoxide - metabolism | Metalloporphyrins - pharmacology | Dose-Response Relationship, Drug | Carbon Monoxide - pharmacology | Cattle | Vasodilator Agents - metabolism | Blood Pressure - drug effects | Blood Pressure - physiology | Hemin - pharmacology | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Muscle, Smooth, Vascular - drug effects | Cell Survival - drug effects | Vasodilator Agents - pharmacology | Vasomotor System - metabolism | Magnetic Resonance Spectroscopy | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Macromolecular Substances | Animals | Organometallic Compounds - metabolism | Iron Carbonyl Compounds | Heart - drug effects | Organometallic Compounds - chemistry | Vasodilator Agents - chemistry | In Vitro Techniques | Organometallic Compounds - pharmacology
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 04/2009, Volume 156, Issue 8, pp. 1256 - 1266
Background and purpose:  The pleiotropic effects of HMG-CoA inhibitors (statins), which include anti-inflammation, antioxidation and immunomodulation, are not... 
endothelium | nitric oxide | peroxynitrite | lipid peroxidation | atherosclerosis and haem oxygenase | Atherosclerosis and haem oxygenase | Lipid peroxidation | Peroxynitrite | Nitric oxide | Endothelium | OXIDATIVE STRESS | ACTIVATION | LIPID-PEROXIDATION | ENDOGENOUS-CARBON-MONOXIDE | LOW-DENSITY-LIPOPROTEIN | ENDOTHELIAL-CELLS | ATHEROSCLEROTIC LESION FORMATION | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | SIMVASTATIN | EXPRESSION | Heme Oxygenase-1 - metabolism | Protoporphyrins - pharmacology | Endothelium, Vascular - drug effects | Male | Endothelium, Vascular - enzymology | Simvastatin - pharmacology | Metalloporphyrins - pharmacology | Hemin - metabolism | Atherosclerosis - enzymology | Time Factors | Lipid Peroxidation - drug effects | Nitric Oxide Synthase Type III - metabolism | Aorta - enzymology | Heptanoic Acids - pharmacology | Disease Models, Animal | Malondialdehyde - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Rabbits | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Aorta - drug effects | Enzyme Inhibitors - pharmacology | Heme Oxygenase-1 - antagonists & inhibitors | Nitric Oxide Synthase Type III - antagonists & inhibitors | Aorta - pathology | Atorvastatin Calcium | Pyrroles - pharmacology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Peroxynitrous Acid - metabolism | Endothelium, Vascular - pathology | Nitric Oxide - metabolism | Arginine - metabolism | Research Papers
Journal Article
Plant, Cell & Environment, ISSN 0140-7791, 05/2013, Volume 36, Issue 5, pp. 956 - 969
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 07/2012, Volume 56, Issue 7, pp. 3700 - 3711
Journal Article