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Journal of Immunology, ISSN 0022-1767, 02/2012, Volume 188, Issue 4, pp. 1953 - 1960
Group B Streptococcus (GBS) is a frequent agent of life-threatening sepsis and meningitis in neonates and adults with predisposing conditions. We tested the... 
RESPONSES | RECOGNITION | INFECTION | SEPSIS | IMMUNOLOGY | CASPASE-1 ACTIVATION | NALP3 INFLAMMASOME | CYTOPLASMIC DNA | HOST-RESISTANCE | INNATE IMMUNITY | CELL-DEATH | Streptococcus agalactiae - immunology | Toll-Like Receptor 2 - genetics | Streptococcus agalactiae - pathogenicity | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Streptococcal Infections - metabolism | Caspase 1 - metabolism | Interleukin-1beta - genetics | Streptococcus agalactiae - metabolism | Cytoskeletal Proteins - deficiency | RNA, Messenger - biosynthesis | Toll-Like Receptor 2 - deficiency | Interleukin-1beta - metabolism | Cytoskeletal Proteins - metabolism | Female | Interleukin-1beta - biosynthesis | Hemolysin Proteins - biosynthesis | Carrier Proteins - immunology | Signal Transduction | Mice, Inbred C57BL | Myeloid Differentiation Factor 88 - genetics | Macrophages - cytology | Mice, Knockout | Carrier Proteins - genetics | Interleukin-18 - biosynthesis | Macrophages - metabolism | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Myeloid Differentiation Factor 88 - deficiency | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Inflammasomes - immunology | Dendritic Cells - microbiology | Bacterial Proteins - biosynthesis | Mice | Streptococcal Infections - immunology | Interleukin-18 - metabolism | Life Sciences | Microbiology and Parasitology | Bacteriology | phagocytosis | cytokines | dendritic cells | bacterial infections | inflammation
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2014, Volume 289, Issue 27, pp. 19098 - 19109
Journal Article
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 5/2019, Volume 103, Issue 10, pp. 4103 - 4112
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2011, Volume 119, Issue 4, pp. 736 - 748
J. Neurochem. (2011) 119, 736–748. Microglia are important innate immune effectors against invading CNS pathogens, such as Staphylococcus aureus (S. aureus), a... 
IL‐1β | NLRP3 | IL‐18 | microglia | inflammasome | P2X7R | IL-1β | IL-18 | P2X | NERVOUS-SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | IL-1 beta | NLRP3 INFLAMMASOME | RESISTANT STAPHYLOCOCCUS-AUREUS | NEUROSCIENCES | NALP3 INFLAMMASOME | TOLL-LIKE | DIFFERENTIAL REQUIREMENT | HOST IMMUNE-RESPONSE | EXPERIMENTAL BRAIN-ABSCESS | P2XR | GENETIC-HETEROGENEITY | ATP RELEASE | Enzyme-Linked Immunosorbent Assay - methods | Microglia - metabolism | Hemolysin Proteins - pharmacology | NLR Family, Pyrin Domain-Containing 3 Protein | Staphylococcus aureus - physiology | Cell Survival - genetics | Cerebral Cortex - cytology | Cytoskeletal Proteins - deficiency | Dose-Response Relationship, Drug | Drug Interactions | Microglia - immunology | Time Factors | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Purinergic P2 Receptor Antagonists - pharmacology | Cytoskeletal Proteins - metabolism | Microglia - microbiology | Animals, Newborn | Cell Survival - drug effects | Microglia - drug effects | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Signal Transduction - genetics | Staphylococcus aureus - pathogenicity | Mice, Knockout | Carrier Proteins - genetics | Bacterial Proteins - pharmacology | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Signal Transduction - drug effects | Bacterial Toxins - pharmacology | Models, Biological | CARD Signaling Adaptor Proteins | Mice | Thiazoles - pharmacology | Interleukin-18 - metabolism | ASC | hemolysins | cathepsin B
Journal Article
Journal Article
Pathogens and Disease, ISSN 2049-632X, 08/2015, Volume 73, Issue 6, p. ftv042
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 131, Issue 2, pp. 421 - 427.e2
Background The skin of patients with atopic dermatitis (AD) has defects in keratinocyte differentiation, particularly in expression of the epidermal barrier... 
Allergy and Immunology | skin barrier | Atopic dermatitis | filaggrin | acid sphingomyelinase | Staphylococcus aureus | α-toxin | BARRIER | MECHANISMS | IMMUNOLOGY | VIRULENCE | PATHOGENESIS | ATOPIC-DERMATITIS | ALLERGY | DISEASE | alpha-toxin | AUREUS | SKIN | MUTATIONS | EXPRESSION | Hemolysin Proteins - immunology | Skin - cytology | Skin - microbiology | Sphingomyelin Phosphodiesterase - immunology | Skin - metabolism | Staphylococcal Infections - pathology | Humans | Cell Death - immunology | Bacterial Toxins - toxicity | Dermatitis, Atopic - microbiology | Dermatitis, Atopic - immunology | Hemolysin Proteins - toxicity | Staphylococcal Infections - microbiology | Cell Death - drug effects | Keratinocytes - enzymology | Skin - immunology | Staphylococcus aureus - metabolism | Cell Survival - drug effects | Intermediate Filament Proteins - immunology | Staphylococcal Infections - immunology | Bacterial Toxins - immunology | Cells, Cultured | Intermediate Filament Proteins - biosynthesis | Dermatitis, Atopic - pathology | Keratinocytes - cytology | Cell Survival - immunology | Keratinocytes - immunology | Cell Differentiation - immunology | Animals | Intermediate Filament Proteins - deficiency | Keratinocytes - drug effects | Cell Differentiation - drug effects | Mice | Mice, Inbred BALB C | Sphingomyelin Phosphodiesterase - secretion
Journal Article
Infection and Immunity, ISSN 0019-9567, 07/2012, Volume 80, Issue 7, pp. 2382 - 2389
Journal Article