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Book
Gastroenterology, ISSN 0016-5085, 2017, Volume 152, Issue 4, pp. 880 - 894.e6
Background & Aims Hepatocellular adenomas (HCAs) are benign liver tumors that can be assigned to molecular subtypes based on inactivating mutations in... 
Gastroenterology and Hepatology | HCC | SHH | Tumor Progression | Benign | HEDGEHOG PATHWAY | FOLLOW-UP | CANCER | TUMORS | SOMATIC MUTATIONS | INACTIVATION | INHIBITION | THERAPEUTIC TARGETS | GASTROENTEROLOGY & HEPATOLOGY | LIVER ADENOMATOSIS | ACTIVATING MUTATIONS | Liver Neoplasms - classification | Hepatocyte Nuclear Factor 1-alpha - genetics | Adenoma - genetics | Cytokine Receptor gp130 - genetics | Humans | Middle Aged | Transcriptome | Hedgehog Proteins - metabolism | Male | Liver Neoplasms - chemistry | GTP-Binding Protein alpha Subunits, Gs - genetics | Young Adult | Protein-Tyrosine Kinases - genetics | Telomerase - genetics | Cell Transformation, Neoplastic - genetics | Carcinoma, Hepatocellular - genetics | Hemorrhage - etiology | Aged, 80 and over | Adult | Chromogranins - genetics | Female | Carcinoma, Hepatocellular - chemistry | Inhibin-beta Subunits - genetics | Neoplasm Proteins - genetics | Child | STAT3 Transcription Factor - genetics | Liver Neoplasms - genetics | Signal Transduction | Zinc Finger Protein GLI1 - genetics | Risk Factors | Janus Kinase 2 - genetics | Gene Fusion | Adenoma - chemistry | beta Catenin - genetics | Sequence Analysis, RNA | Adenoma - classification | Adolescent | Carcinoma, Hepatocellular - pathology | Aged | Mutation | Liver cancer | Liver | Risk factors | Adenoma | Life Sciences | Human health and pathology | Santé publique et épidémiologie | Hépatology and Gastroenterology | Tissues and Organs
Journal Article
Clinical Immunology, ISSN 1521-6616, 2016, Volume 163, pp. 60 - 65
Abstract Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a monogenic autoimmune disease characterized by early-onset... 
Allergy and Immunology | Autoimmunity | IPEX | Mutation | FOXP3 | Primary immunodeficiency | X-LINKED SYNDROME | ENTEROPATHY | STABILITY | IMMUNOLOGY | IMMUNE DYSREGULATION | DIMER | SEQUENCE | DISEASE | REGULATORY T-CELLS | POLYENDOCRINOPATHY | IMMUNODYSREGULATION | Eczema - genetics | Eczema - immunology | Immune System Diseases - genetics | Humans | Diabetes Mellitus, Type 1 - congenital | Infant | Male | Meningoencephalitis - immunology | Thrombocytopenia - genetics | Immunoglobulin E - immunology | Diarrhea - immunology | Eosinophilia - genetics | Fatal Outcome | Hepatomegaly - immunology | Genetic Diseases, X-Linked - genetics | Diabetes Mellitus, Type 1 - immunology | Dimerization | Hemorrhage - genetics | Sepsis - immunology | Splenomegaly - genetics | Growth Disorders - immunology | Hemorrhage - immunology | Splenomegaly - immunology | Thrombocytopenia - immunology | Immune System Diseases - immunology | Leukocytosis - immunology | Meningoencephalitis - genetics | Diabetes Mellitus, Type 1 - genetics | Models, Molecular | Klebsiella Infections - genetics | Hepatomegaly - genetics | Forkhead Transcription Factors - genetics | Sepsis - genetics | Lung Diseases - immunology | Genetic Diseases, X-Linked - immunology | Immune System Diseases - congenital | Thymus Gland - abnormalities | Lung Diseases - genetics | Eosinophilia - immunology | Diarrhea - genetics | Klebsiella Infections - immunology | Phenylalanine - genetics | Hydrophobic and Hydrophilic Interactions | Growth Disorders - genetics | Leukocytosis - genetics
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2010, Volume 30, Issue 6, pp. 1118 - 1126
OBJECTIVE—Regulation of vascular smooth muscle (VSM) proliferation and contractile differentiation is an important factor in vascular development and... 
Molecular biology | Contractile proteins | Vascular biology | Vascular muscle | molecular biology | ACTIVATION | PHENOTYPE | vascular biology | ACTIN DYNAMICS | PROLIFERATION | DICER | vascular muscle | MOUSE DEVELOPMENT | NEOINTIMAL LESION FORMATION | EMBRYONIC STEM-CELLS | SERUM RESPONSE FACTOR | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | contractile proteins | Endoribonucleases - genetics | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Transcriptional Activation | Actins - metabolism | Male | MicroRNAs - metabolism | Aorta - metabolism | Muscle, Smooth, Vascular - physiopathology | Muscle, Smooth, Vascular - embryology | Cell Differentiation - genetics | Vasodilation - genetics | Transfection | Gene Expression Regulation, Developmental | DEAD-box RNA Helicases - deficiency | Trans-Activators - genetics | Hemorrhage - embryology | Endoribonucleases - deficiency | Nuclear Proteins - genetics | Microfilament Proteins - genetics | Vasoconstriction - genetics | Liver Diseases - embryology | Hemorrhage - genetics | Liver Diseases - genetics | Umbilical Arteries - pathology | Muscle, Smooth, Vascular - ultrastructure | Cells, Cultured | Umbilical Arteries - embryology | Aorta - embryology | Genotype | Nuclear Proteins - metabolism | Hemorrhage - metabolism | Gestational Age | Mice, Knockout | Aorta - pathology | Muscle Proteins - genetics | DEAD-box RNA Helicases - genetics | Embryo Loss | Phenotype | Stress Fibers - metabolism | Animals | Ribonuclease III | Muscle Development - genetics | Trans-Activators - metabolism | Mice | Liver Diseases - metabolism | Integrases - genetics | Umbilical Arteries - metabolism
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2017, Volume 112, pp. 336 - 349
Aberrant modulation of mitochondrial dynamic network, which shifts the balance of fusion and fission towards fission, is involved in brain damage of various... 
Mdivi-1 | Inflammation | Early brain injury | Blood-brain barrier disruption | Subarachnoid hemorrhage | Apoptosis | OXYGEN SPECIES PRODUCTION | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEX I INHIBITOR | HIPPOCAMPAL-NEURONS | RAT MODEL | MITOCHONDRIAL FISSION | CELL-DEATH | SIGNALING PATHWAY | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | NF-KAPPA-B | Interleukin-6 - antagonists & inhibitors | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Proto-Oncogene Proteins c-bcl-2 - agonists | Tumor Necrosis Factor-alpha - genetics | Male | NF-kappa B - metabolism | Interleukin-1beta - genetics | Subarachnoid Space - drug effects | Occludin - metabolism | Matrix Metalloproteinase 9 - metabolism | Interleukin-1beta - metabolism | Matrix Metalloproteinase 9 - genetics | Subarachnoid Hemorrhage - mortality | Zonula Occludens-1 Protein - metabolism | Interleukin-6 - metabolism | Subarachnoid Hemorrhage - drug therapy | Interleukin-1beta - antagonists & inhibitors | Zonula Occludens-1 Protein - genetics | NF-kappa B - antagonists & inhibitors | Endoplasmic Reticulum Stress - drug effects | Interleukin-6 - genetics | bcl-2-Associated X Protein - metabolism | Dynamins - genetics | Rats | Subarachnoid Hemorrhage - genetics | Rats, Sprague-Dawley | Blood-Brain Barrier - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Survival Analysis | Subarachnoid Space - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dynamins - metabolism | Mitochondrial Dynamics - genetics | Claudin-5 - metabolism | Occludin - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Mitochondria - genetics | Quinazolinones - pharmacology | bcl-2-Associated X Protein - genetics | Dynamins - antagonists & inhibitors | Claudin-5 - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Subarachnoid Hemorrhage - pathology | bcl-2-Associated X Protein - antagonists & inhibitors | Blood-Brain Barrier - drug effects | Animals | Mitochondrial Dynamics - drug effects | NF-kappa B - genetics | Subarachnoid Space - pathology | Proto-Oncogene Proteins c-bcl-2 - genetics | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Stroke (Disease) | Proteins | Medical research | Brain | Neurons | Analysis | Medicine, Experimental | Brain damage | Injuries
Journal Article
PLOS Genetics, ISSN 1553-7390, 2014, Volume 10, Issue 1, p. e1004134
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e86286
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2014, Volume 192, Issue 12, pp. 5984 - 5992
Journal Article
Science, ISSN 0036-8075, 11/2014, Volume 346, Issue 6212, pp. 987 - 991
Journal Article