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The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 5, pp. 431 - 441
Journal Article
Nature Communications, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, p. 11037
Excessive activation of blood coagulation and neutrophil accumulation have been described in several human cancers. However, whether hypercoagulation and... 
COLON-CANCER | COMPLEMENT | ACTIVATION | RISK-FACTORS | VENOUS THROMBOEMBOLISM | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | MOLECULAR-WEIGHT HEPARIN | MOUSE MODEL | EXTRACELLULAR DNA TRAPS | TISSUE FACTOR
Journal Article
Endoscopy, ISSN 0013-726X, 03/2008, Volume 26, Issue 4, pp. 338 - 341
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2015, Volume 373, Issue 6, pp. 511 - 520
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 11/2016, Volume 36, Issue 11, pp. 2143 - 2151
APC (activated protein C), derived from the plasma protease zymogen, is antithrombotic and anti-inflammatory. In preclinical injury models, recombinant APC... 
neurogenesis | endothelial cells | anticoagulant | neurons | stroke | FOCAL ISCHEMIC-STROKE | TISSUE-PLASMINOGEN ACTIVATOR | REDUCED ANTICOAGULANT ACTIVITY | HIPPOCAMPAL-NEURONS | RECEPTOR 1 | ENDOTHELIAL-CELLS | COAGULATION-FACTOR VA | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | GLUTAMATE EXCITOTOXICITY | BRAIN | Neuroprotective Agents - therapeutic use | Recombinant Proteins - therapeutic use | Endothelial Protein C Receptor | Neurons - pathology | Reperfusion Injury - etiology | Receptor, PAR-1 - metabolism | Humans | Brain Ischemia - metabolism | Recombinant Proteins - adverse effects | Antigens, CD - metabolism | Brain - metabolism | Stroke - pathology | Intracranial Thrombosis - drug therapy | Neurogenesis - drug effects | Neurons - metabolism | Neuroprotective Agents - adverse effects | Neurons - drug effects | Reperfusion Injury - metabolism | Hemostasis - drug effects | Intracranial Thrombosis - pathology | Reperfusion Injury - pathology | Endothelial Cells - metabolism | Receptors, Cell Surface - agonists | Receptors, Cell Surface - metabolism | Stroke - drug therapy | Intracranial Thrombosis - metabolism | Brain - drug effects | Stroke - metabolism | Animals | Reperfusion Injury - prevention & control | Signal Transduction - drug effects | Brain Ischemia - drug therapy | Brain Ischemia - pathology | Brain - pathology | Endothelial Cells - pathology | Thrombolytic Therapy - adverse effects | Protein C - adverse effects | Protein C - therapeutic use | Endothelial Cells - drug effects | Receptor Cross-Talk - drug effects
Journal Article
Scientific Reports, ISSN 2045-2322, 05/2016, Volume 6, Issue 1, p. 25518
Journal Article
Circulation, ISSN 0009-7322, 05/2011, Volume 123, Issue 17, pp. 1891 - 1899
Background-Blocking of glycoprotein VI-dependent pathways by interfering in vascular collagen sites is commonly seen as an attractive target for an... 
stroke | platelet aggregation inhibitors | platelet adhesion | glycoprotein VI | platelet aggregation | CARDIAC & CARDIOVASCULAR SYSTEMS | FAB FRAGMENT | THROMBUS FORMATION | ACUTE CORONARY SYNDROME | ADHESION | CLOPIDOGREL | IN-VIVO | PERIPHERAL VASCULAR DISEASE | SOLUBLE GPVI | MICE | HEMATOLOGY | ANTITHROMBOTIC PROTECTION | EXPRESSION | Injections, Intravenous | Cricetulus | Recombinant Fusion Proteins - adverse effects | Humans | Male | Immunoglobulin Fc Fragments - administration & dosage | Dose-Response Relationship, Drug | Young Adult | Platelet Aggregation Inhibitors - administration & dosage | Platelet Membrane Glycoproteins - administration & dosage | Adult | Platelet Membrane Glycoproteins - adverse effects | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - pharmacokinetics | Immunoglobulin Fc Fragments - adverse effects | Recombinant Fusion Proteins - administration & dosage | CHO Cells | Platelet Aggregation Inhibitors - adverse effects | Hemostasis - drug effects | Platelet Membrane Glycoproteins - pharmacokinetics | Cricetinae | Glycoproteins - administration & dosage | Collagen - administration & dosage | Animals | Platelet Count | Recombinant Fusion Proteins - pharmacokinetics | Aggregation | Safety and security measures | Blood platelets | Hemostasis | Patient outcomes | Atherosclerosis | Dosage and administration | Research | Drug therapy
Journal Article
Blood, ISSN 0006-4971, 08/2011, Volume 118, Issue 6, pp. 1663 - 1674
Journal Article