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Biochimica et Biophysica Acta - General Subjects, ISSN 0304-4165, 2014, Volume 1840, Issue 6, pp. 2032 - 2041
Background Malaria is an extremely devastating disease that continues to affect millions of people each year. A distinctive attribute of malaria infected red... 
Plasmodium falciparum | Hemozoin structure | Hemozoin biophysical properties | Hemozoin synthesis | Hemoglobin degradation
Journal Article
Analyst, ISSN 0003-2654, 01/2018, Volume 143, Issue 1, pp. 157 - 163
During malarial infection, the host uses the spleen to clear the malaria parasites, however, the parasites have evolved the ability to bind to endothelial... 
CHEMISTRY, ANALYTICAL | HEMOZOIN | SPLEEN | SPECTROSCOPY | BLOOD | TOOL
Journal Article
Parasitology, ISSN 0031-1820, 08/2001, Volume 123, Issue 2, pp. 125 - 131
Haem from host erythrocyte (RBC) haemoglobin is polymerized in the digestive organelle of Plasmodium falciparum to haemozoin (HZ), a crystalline, insoluble... 
hemozoin
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 02/2016, Volume 22, Issue 2, pp. 343 - 343
Journal Article
Acta Tropica, ISSN 0001-706X, 11/2019, Volume 199, p. 105109
High-grade chloroquine (CQ) resistance has been reported in malaria endemic geographical regions such as Papua New Guinea, northern Papua, and eastern and... 
Synergistic | Dihydroartemisinin | Isobologram | Combination therapy | Hemozoin
Journal Article
Electrochimica Acta, ISSN 0013-4686, 11/2011, Volume 56, Issue 27, pp. 9762 - 9768
We report an evaluation of the reactivity of hemozoin (HZ) and β-hemozoin (β-HZ) obtained from the Triatoma , alone and in combination with quinine and... 
Meccus longipennis | Antimalarials | Voltammetry | Hemozoin | β-Hemozoin | ELECTROCHEMISTRY | SCHISTOSOMA-MANSONI | HAEMOZOIN | POLYMERIZATION | INSECT | beta-Hemozoin | GALVANIC INTERACTIONS | INHIBITION | HEMATIN MALARIA PIGMENT | HEME DETOXIFICATION | CYCLIC VOLTAMMETRY | TROPHOZOITES
Journal Article
by Yu, X and Du, Y and Cai, CM and Cai, BW and Zhu, MT and Xing, CS and Tan, P and Lin, M and Wu, J and Li, J and Wang, MJ and Wang, HY and Su, XZ and Wang, RF
NATURE COMMUNICATIONS, ISSN 2041-1723, 11/2018, Volume 9
The inflammasome plays a critical role in inflammation and immune responses against pathogens. However, whether or how inflammasome activation regulates type I... 
PLASMACYTOID DENDRITIC CELLS | PATHWAYS | INTERFERON | HEMOZOIN | DNA | MULTIDISCIPLINARY SCIENCES | INNATE | NLRP3 | IL-1-BETA | MALARIA IMMUNITY | INDUCTION
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 01/2001, Volume 194, Issue 2, pp. 175 - 179
Haemozoin, the malaria pigment, regulates the synthesis of several host cytokines and has been found to be associated with the disease severity. Here we... 
hemozoin
Journal Article
Scientific Reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, p. 1431
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2018, Volume 9, Issue 10, pp. 980 - 985
Based on the idea that compounds designed to exhibit high affinity for heme would block hemozoin formation, a critical heme-detoxification process for malarial... 
Antimalarial | molecular recognition | hemozoin | heme | heme detoxification protein | DRUG | ANTIPLASMODIAL ACTIVITY | BISQUINOLINES | CHEMISTRY, MEDICINAL | ACTIVITY IN-VIVO | BLOOD-STAGES | CHLOROQUINE | HEMOZOIN FORMATION | PLASMODIUM-FALCIPARUM | MALARIA | HEMATIN POLYMERIZATION
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 7610 - 12
A key drug target for malaria has been the detoxification pathway of the iron-containing molecule heme, which is the toxic byproduct of hemoglobin digestion.... 
CRYSTALLIZATION | MECHANISM | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | DIGESTIVE VACUOLE MEMBRANE | ULTRASTRUCTURE | RED-BLOOD-CELLS | NUCLEATION | FERRIPROTOPORPHYRIN-IX | PIGMENT BETA-HEMATIN | HEMOZOIN FORMATION | Malaria | Microscopy | Ultrastructure | Hemozoin | Crystals | Crystallization | Heme | Detoxification | Tomography | Hemoglobin | Parasites | Drug development
Journal Article
Natural Product Research, ISSN 1478-6419, 2019, pp. 1 - 5
A polyphenolic flavonoid, Silymarin isolated from Silybum marianum is widely known for its hepatoprotective action. In the present study anti-plasmodial... 
chloroquine | Silymarin | hemozoin | heme | β-haematin | P. falciparum
Journal Article
Journal of Peptide Science, ISSN 1075-2617, 09/2019, Volume 25, Issue 9, pp. e3203 - n/a
Journal Article