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Acta biomaterialia, ISSN 1742-7061, 03/2019, Volume 86, pp. 135 - 147
.... Heparin-binding EGF-like growth factor (HB-EGF) bound to GAG in biomaterials (e.g. hydrogels) might serve as a reservoir that induces prolonged activation of the EGF receptor... 
Hyaluronan | Sulfated hyaluronan | Wound healing | Extracellular matrix (ECM) | Fibroblasts | Surface plasmon resonance | Hydrogel | Heparin-binding epidermal growth factor-like growth factor (HB-EGF) | Biomimetic material | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Heparin-binding EGF-like Growth Factor - pharmacology | Glycosaminoglycans - metabolism | Epidermis - drug effects | Humans | Hyaluronic Acid - chemistry | Rats | Collagen - chemistry | Hyaluronic Acid - pharmacology | Sulfates - pharmacology | Thermodynamics | Animals | Swine | Delayed-Action Preparations - pharmacology | Fibroblasts - drug effects | Sulfates - chemistry | Collagen - pharmacology | Hydrogels - pharmacology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Wound Healing - drug effects | Hydrogels - chemistry | Biological products | Epidermal growth factor | Biomimetics | Collagen | Analysis | Anticoagulants (Medicine) | Skin | Heparin | Sulfates | Hyaluronic acid | Protein binding | Glycosaminoglycans | Hydrogels | Leukocyte migration | Collagens | Molecular dynamics | Molecular docking | Biomaterials | Proteins | Biomedical materials | Immunology | Growth factors | Controlled release | Binding | Gels | Dressings | Epidermal growth factor receptors | Keratinocytes | Derivatives | Biological activity | Sulfation | Dynamic tests | Molecular modelling | Computer applications | Organ culture | Sustained release | Index Medicus
Journal Article
Journal Article