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Human Molecular Genetics, ISSN 0964-6906, 2014, Volume 23, Issue 15, pp. 4077 - 4085
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2015, Volume 289, Issue 2, pp. 163 - 176
SIRT1 (silent information regulator 1), a conserved NAD +-dependent histone deacetylase, is closely related with various biological processes. Moreover, the... 
Reversion | MALAT1 | Liver fibrosis | SIRT1 | Apoptosis | RESVERATROL | METASTASIS | MECHANISMS | CANCER | HEPATIC-FIBROSIS | RENAL FIBROSIS | LONG NONCODING RNA | MALAT-1 | PHARMACOLOGY & PHARMACY | TOXICOLOGY | EXPRESSION | PULMONARY-FIBROSIS | Sirtuin 1 - metabolism | Liver - pathology | Liver - enzymology | Apoptosis - drug effects | Carbon Tetrachloride | Humans | Actins - metabolism | Myofibroblasts - enzymology | Male | RNA, Messenger - metabolism | Xanthines - pharmacology | Sirtuin 1 - genetics | Actins - genetics | Dose-Response Relationship, Drug | Liver Cirrhosis, Experimental - prevention & control | Liver Cirrhosis, Experimental - enzymology | Collagen Type I - genetics | Dexamethasone - pharmacology | Transfection | Liver - drug effects | RNA Interference | Time Factors | Liver Cirrhosis, Experimental - pathology | Female | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - enzymology | Chemical and Drug Induced Liver Injury - etiology | Hepatic Stellate Cells - pathology | Transforming Growth Factor beta1 - pharmacology | Hepatic Stellate Cells - drug effects | Cell Line | Chemical and Drug Induced Liver Injury - prevention & control | Insulin - pharmacology | Myofibroblasts - pathology | Collagen Type I - metabolism | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Hepatic Stellate Cells - enzymology | Chemical and Drug Induced Liver Injury - genetics | Liver Cirrhosis, Experimental - genetics | Phenotype | Animals | Liver Cirrhosis, Experimental - chemically induced | RNA, Long Noncoding - metabolism | Corticosteroids | Liver | Analysis | Fibrosis | Bone morphogenetic proteins | Transforming growth factors | Liver cirrhosis | Index Medicus | APOPTOSIS | DEXAMETHASONE | COLLAGEN | RNA | LUNGS | METASTASES | 60 APPLIED LIFE SCIENCES | HISTONES | MICE | VIRUSES | FIBROSIS | ONCOGENES | TRANSCRIPTION FACTORS | ACTIN | MATERIALS RECOVERY | STEROLS | TRANSCRIPTION | PHENOTYPE | INSULIN | NAD | GROWTH FACTORS | CARBON TETRACHLORIDE | LIVER | CARCINOMAS | RECEPTORS | MUSCLES
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 143, Issue 5, pp. 1319 - 1329.e11
Background & Aims The pathogenesis of cirrhosis, a disabling outcome of defective liver repair, involves deregulated accumulation of myofibroblasts derived... 
Gastroenterology and Hepatology | Gene Regulation | Signal Transduction | Liver Disease | Mouse Model | PARTIAL-HEPATECTOMY | ACTIVATION | TISSUE-REPAIR | SIGNALS | PATHWAY | LIVER-REGENERATION | IN-VIVO | MICE | GASTROENTEROLOGY & HEPATOLOGY | TUMOR-GROWTH | UP-REGULATION | Carbon Tetrachloride | Humans | Actins - metabolism | Hedgehog Proteins - metabolism | Hepatic Stellate Cells - metabolism | Myofibroblasts - enzymology | Male | Cell Transdifferentiation - genetics | Gene Expression Profiling | RNA, Messenger - metabolism | Hepatic Stellate Cells - cytology | Hypoxia-Inducible Factor 1, alpha Subunit | Liver Cirrhosis - chemically induced | Actins - genetics | Glycolysis - genetics | Myofibroblasts - metabolism | Mitochondria | Ligation | Hedgehog Proteins - genetics | Time Factors | Liver Cirrhosis - metabolism | Liver Cirrhosis - genetics | Pyruvate Kinase - metabolism | Lactic Acid - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Hepatic Stellate Cells - enzymology | Rats | Signal Transduction - genetics | Animals | Bile Ducts | Mice | Pyruvate Kinase - genetics | Liver diseases | Gliomas | Actin | Analysis | Genes | Physiological aspects | Fluorescence | Drug resistance | Muscle proteins | Fructose | Lactates | Glucose metabolism | Liver | Cellular signal transduction | Liver cirrhosis | mouse model | liver disease | signal transduction | gene regulation
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e45285
A role for the NADPH oxidases NOX1 and NOX2 in liver fibrosis has been proposed, but the implication of NOX4 is poorly understood yet. The aim of this work was... 
GROWTH-FACTOR-BETA | OXIDATIVE STRESS | TGF-BETA | INDUCED APOPTOSIS | ADENINE-DINUCLEOTIDE PHOSPHATE | MULTIDISCIPLINARY SCIENCES | FIBROGENESIS | DIFFERENTIATION | MESENCHYMAL TRANSITION | UP-REGULATION | Liver - virology | Hepatitis C, Chronic - pathology | Liver - enzymology | Gene Expression - drug effects | Apoptosis - drug effects | ATP Binding Cassette Transporter, Sub-Family B - deficiency | Carbon Tetrachloride | Humans | NADPH Oxidases - metabolism | Hepatitis C, Chronic - virology | Myofibroblasts - enzymology | Liver Cirrhosis - enzymology | Liver Cirrhosis - chemically induced | Liver - drug effects | Cell Transdifferentiation - drug effects | Hepatitis C, Chronic - enzymology | STAT3 Transcription Factor - deficiency | NADPH Oxidases - genetics | Hepacivirus - physiology | Hepatic Stellate Cells - virology | Myofibroblasts - virology | Hepatocytes - drug effects | STAT3 Transcription Factor - genetics | Hepatic Stellate Cells - drug effects | Cyclin-Dependent Kinase Inhibitor p16 - deficiency | Hepatic Stellate Cells - enzymology | Cyclin-Dependent Kinase Inhibitor p16 - genetics | NADPH Oxidase 4 | Myofibroblasts - drug effects | Mice, Knockout | Transforming Growth Factor beta - pharmacology | Animals | Liver Cirrhosis - virology | Signal Transduction - drug effects | Biopsy | Hepatocytes - virology | Liver Cirrhosis - pathology | Mice | ATP Binding Cassette Transporter, Sub-Family B - genetics | Hepatocytes - enzymology | Oxidases | Care and treatment | Liver diseases | Research | Gene expression | Liver cells | Animal models | Biomedical research | Mesenchyme | Liver | Carbon tetrachloride | Viruses | Activation | Metastasis | Experiments | NAD(P)H oxidase | Hepatitis | Genotype & phenotype | Cell activation | NOX4 protein | Rodents | Hepatology | Gastroenterology | CYBB protein | Fibroblasts | Growth factors | Medical research | Stellate cells | Patients | Pulmonary fibrosis | Hepatocytes | Cell death | Fibrosis | Hepatitis C virus | Hepatitis C | Cancer | Apoptosis | Bile | Malalties del fetge | Cèl·lules hepàtiques
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 02/2013, Volume 109, Issue 3, pp. 394 - 401
Plant-based whole foods provide thousands of bioactive metabolites to the human diet that reduce the risk of developing chronic diseases. beta-Caryophyllene... 
β-Caryophyllene | Antioxidants | Hepatic stellate cells | Liver fibrosis | APOPTOSIS | ACID | ROSMARINUS-TOMENTOSUS | MECHANISM | COMPONENTS | SESQUITERPENE | PROLIFERATION | PEROXIDATION | THIOACETAMIDE | NUTRITION & DIETETICS | beta-Caryophyllene | EXPRESSION | Liver - pathology | Sesquiterpenes - metabolism | Rats, Wistar | Antioxidants - metabolism | Probucol - therapeutic use | Hepatic Stellate Cells - metabolism | Sesquiterpenes - administration & dosage | Carbon Tetrachloride Poisoning - prevention & control | Sesquiterpenes - therapeutic use | Probucol - pharmacology | Carbon Tetrachloride Poisoning - metabolism | Liver - drug effects | Arachidonate 5-Lipoxygenase - chemistry | Lipid Peroxidation - drug effects | Female | Flavoring Agents - therapeutic use | Free Radical Scavengers - therapeutic use | alpha-Tocopherol - metabolism | Hepatic Stellate Cells - drug effects | Cell Line | Cell Survival - drug effects | Arachidonate 5-Lipoxygenase - metabolism | Free Radical Scavengers - metabolism | Liver - metabolism | Hepatic Stellate Cells - enzymology | Free Radical Scavengers - administration & dosage | Lipoxygenase Inhibitors - therapeutic use | Rats | Flavoring Agents - metabolism | Antioxidants - pharmacology | Random Allocation | Flavoring Agents - administration & dosage | Carbon Tetrachloride Poisoning - pathology | Lipoxygenase Inhibitors - administration & dosage | alpha-Tocopherol - therapeutic use | Antioxidants - therapeutic use | Animals | Antioxidants - administration & dosage | Lipoxygenase Inhibitors - metabolism | Oxidative Stress - drug effects | Dietary Supplements
Journal Article
Liver International, ISSN 1478-3223, 04/2015, Volume 35, Issue 4, pp. 1222 - 1233
Journal Article
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 11/2013, Volume 272, Issue 3, pp. 713 - 725
Journal Article
Life Sciences, ISSN 0024-3205, 06/2016, Volume 155, pp. 155 - 160
Journal Article