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Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7456, pp. 97 - 101
Obesity has become more prevalent in most developed countries over the past few decades, and is increasingly recognized as a major risk factor for several... 
HEPATOCELLULAR-CARCINOMA | HEPATIC STELLATE CELLS | ACID | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | PHENOTYPE | BACTERIUM | MECHANISMS | STRESS | EXPRESSION | CLOSTRIDIUM | Fatty Liver - pathology | Carcinoma, Hepatocellular - prevention & control | Humans | Fatty Liver - complications | Cellular Senescence - drug effects | Hepatic Stellate Cells - metabolism | Liver Neoplasms - complications | Male | Hepatic Stellate Cells - cytology | Interleukin-1beta - deficiency | Liver Neoplasms - etiology | Carcinoma, Hepatocellular - complications | Dietary Fats - pharmacology | Non-alcoholic Fatty Liver Disease | Carcinoma, Hepatocellular - etiology | Disease Models, Animal | Hepatic Stellate Cells - drug effects | DNA Damage - drug effects | Hepatic Stellate Cells - secretion | Liver Neoplasms - prevention & control | Bacteria - metabolism | Dietary Fats - adverse effects | Obesity - chemically induced | Cytokines - metabolism | Deoxycholic Acid - blood | Mice, Inbred C57BL | Risk Factors | Cells, Cultured | Cytokines - secretion | Gastrointestinal Tract - microbiology | Bile Acids and Salts - metabolism | Gastrointestinal Tract - drug effects | Gastrointestinal Tract - metabolism | Obesity - metabolism | Phenotype | Animals | Deoxycholic Acid - metabolism | Liver Neoplasms - metabolism | Anti-Bacterial Agents - pharmacology | Mice | Carcinoma, Hepatocellular - metabolism | Liver cancer | Obesity | Microbial metabolism | Development and progression | Genetic aspects | Research | Health aspects | Proteins | Cell growth | Weight control | Rodents | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 143, Issue 3, pp. 765 - 776.e3
Background & Aims Interleukin (IL)-17 signaling has been implicated in lung and skin fibrosis. We examined the role of IL-17 signaling in the pathogenesis of... 
Gastroenterology and Hepatology | Immune Response | Myofibroblast | Mouse Model | Bone Marrow-Derived Macrophages | RAT-LIVER | TARGET | IL-17 RECEPTOR | HEPATOCYTES | FAMILY-MEMBERS | STAT3 | TRANSDUCTION | PATHWAY | DISEASE | GENE-EXPRESSION | GASTROENTEROLOGY & HEPATOLOGY | Kupffer Cells - pathology | Liver - pathology | Carbon Tetrachloride | Humans | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Receptors, Interleukin-17 - genetics | Interleukin-23 - genetics | Receptors, Interleukin-17 - deficiency | Interleukins - genetics | Liver Cirrhosis, Experimental - prevention & control | Liver - immunology | Time Factors | Bone Marrow Transplantation | Liver Cirrhosis, Alcoholic - immunology | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-17 - administration & dosage | Liver Cirrhosis, Experimental - immunology | Signal Transduction | Liver Cirrhosis, Alcoholic - pathology | Liver - metabolism | Interleukin-17 - genetics | Genotype | Bile Ducts - surgery | Disease Progression | Mice, Knockout | Interleukin-17 - metabolism | Phenotype | Interleukins - deficiency | Mice | Liver Cirrhosis, Experimental - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation Mediators - administration & dosage | Liver Cirrhosis, Experimental - etiology | Interleukin-23 - deficiency | Ligation | Hepatic Stellate Cells - immunology | Inflammation Mediators - metabolism | STAT3 Transcription Factor - deficiency | Liver Cirrhosis, Experimental - pathology | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Cell Line | Interleukin-1 - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-17 - deficiency | Liver Cirrhosis, Experimental - genetics | Animals | Interleukins - administration & dosage | Kupffer Cells - immunology | Medical colleges | Liver diseases | Liver | Carbon tetrachloride | Transforming growth factors | Muscle proteins | Macrophages | Endothelium | Messenger RNA | Interleukins | Actin | Analysis | Collagen | Fibrosis | Liver cirrhosis | Index Medicus | Abridged Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 143, Issue 4, pp. 1073 - 1083.e22
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 07/2017, Volume 32, Issue 7, pp. 1387 - 1393
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 142, Issue 4, pp. 938 - 946
Background & Aims The pathogenesis of liver fibrosis involves activation of hepatic stellate cells, which is associated with depletion of intracellular lipid... 
Gastroenterology and Hepatology | Inflammation | Myofibroblasts | Energy Depletion | Mouse Model | RAT-LIVER | FIBROSIS | PATHWAY | DISEASE | MECHANISMS | RETINOL | GASTROENTEROLOGY & HEPATOLOGY | Liver - pathology | Kidney - pathology | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Carbon Tetrachloride | Humans | Hepatic Stellate Cells - metabolism | Autophagy - drug effects | Idiopathic Pulmonary Fibrosis - metabolism | Kidney - metabolism | Epoxy Compounds - pharmacology | Liver - drug effects | RNA Interference | Adenosine Triphosphate - metabolism | Liver Cirrhosis, Experimental - pathology | Lung - metabolism | Autophagy - genetics | Microtubule-Associated Proteins - deficiency | Hepatic Stellate Cells - pathology | Fibroblasts - metabolism | Hepatic Stellate Cells - drug effects | Cell Line | Lung - pathology | Oleic Acid - metabolism | Adenine - analogs & derivatives | Liver - metabolism | Mice, Inbred C57BL | Adenine - pharmacology | Liver Cirrhosis, Experimental - genetics | Fibroblasts - pathology | Mice, Knockout | Thioacetamide | Autophagy-Related Protein 7 | Animals | Autophagy-Related Protein 5 | Energy Metabolism | Fibroblasts - drug effects | Liver Cirrhosis, Experimental - chemically induced | Lipid Metabolism - drug effects | Idiopathic Pulmonary Fibrosis - pathology | Mice | Liver Cirrhosis, Experimental - metabolism | Phosphates | Medical colleges | Neurosciences | Platelet-derived growth factor | Liver diseases | Albumin | Lipids | Muscle proteins | Fatty acids | Cells | Monosaccharides | Unsaturated fatty acids | Monounsaturated fatty acids | Actin | Analysis | Intermediate filament proteins | Sugars | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 6, pp. 2324 - 2329
In many organs, myofibroblasts play a major role in the scarring process in response to injury. In liver fibrogenesis, hepatic stellate cells (HSCs) are... 
Phenotypes | Hepatocytes | Epithelial cells | Liver | Fibrosis | Cell lines | Antibodies | Hepatic stellate cells | Myofibroblasts | Liver cells | Epithelial-mesenchymal transition | Alpha-smooth muscle actin | Glisson's capsule | Podoplanin | alpha-smooth muscle actin | PATHWAYS | ACID | RAT | MULTIDISCIPLINARY SCIENCES | MOUSE | RECEPTOR | POPULATIONS | podoplanin | SMOOTH-MUSCLE | fibrosis | LINEAGE | Liver - pathology | WT1 Proteins - metabolism | Membrane Glycoproteins - metabolism | Hepatic Stellate Cells - metabolism | RNA, Messenger - metabolism | Liver - injuries | Myofibroblasts - metabolism | Biliary Tract - metabolism | Cell Transdifferentiation - drug effects | Liver Cirrhosis - metabolism | Chemical and Drug Induced Liver Injury - pathology | WT1 Proteins - genetics | Hepatic Stellate Cells - pathology | Liver Cirrhosis - etiology | Myofibroblasts - pathology | Epithelium - pathology | Gene Expression | Liver Regeneration | Epithelium - metabolism | Signal Transduction | Liver - metabolism | RNA, Messenger - genetics | Cells, Cultured | Mice, Transgenic | Chemical and Drug Induced Liver Injury - genetics | Carbon Tetrachloride - toxicity | Biliary Tract - pathology | Nerve Tissue Proteins - metabolism | Cell Lineage | Transforming Growth Factor beta - pharmacology | Animals | Chemical and Drug Induced Liver Injury - metabolism | Liver Cirrhosis - pathology | Mesoderm - metabolism | Mice | Mesoderm - pathology | Transforming Growth Factor beta - metabolism | Glycoproteins | Liver diseases | Rodents | Cells | Tumors | Index Medicus | Biological Sciences
Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 01/2014, Volume 59, Issue 1, pp. 154 - 169
Journal Article
Journal Article