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Journal of Hepatology, ISSN 0168-8278, 2013, Volume 60, Issue 4, pp. 723 - 731
Background & Aims Chronic hepatitis B and hepatitis D are global health problems caused by the human hepatitis B and hepatitis D virus. The myristoylated preS1... 
Gastroenterology and Hepatology | Viral entry | Immunosuppressive | Sodium taurocholate cotransporting polypeptide | Tacrolimus | Myrcludex B | Cyclosporin A | Hepatitis D | Binding domain | Hepatitis B | HEPATOCYTES | LIVER-TRANSPLANTATION | PROTEIN | DETERMINANTS | CHOLESTASIS | INFECTIVITY | TAUROCHOLATE COTRANSPORTING POLYPEPTIDE | TRANSPORT | REPLICATION | C VIRUS | GASTROENTEROLOGY & HEPATOLOGY | Cyclosporine - pharmacology | Hepatitis B virus - pathogenicity | Lipopeptides - pharmacology | Humans | Host-Pathogen Interactions - drug effects | Hepatitis Delta Virus - pathogenicity | Virus Internalization - drug effects | Organic Anion Transporters, Sodium-Dependent - genetics | Genetic Variation | Cyclophilins - pharmacology | Symporters - antagonists & inhibitors | Tacrolimus - pharmacology | Hepatitis Delta Virus - drug effects | Mutant Proteins - antagonists & inhibitors | Protein Structure, Tertiary | Cell Line | Hepatitis Delta Virus - physiology | Organic Anion Transporters, Sodium-Dependent - antagonists & inhibitors | Cells, Cultured | Mutant Proteins - genetics | Mutant Proteins - metabolism | Binding Sites - genetics | Hepatitis B virus - physiology | Symporters - metabolism | Hep G2 Cells | Hepatitis B virus - drug effects | Symporters - genetics | Cell Line, Tumor | Organic Anion Transporters, Sodium-Dependent - metabolism | Host-Pathogen Interactions - physiology | Cyclosporine | Protein binding
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2015, Volume 11, Issue 4, p. e1004840
Hepatitis D virus (HDV) is the smallest virus known to infect human. About 15 million people worldwide are infected by HDV among those 240 million infected by... 
COTRANSPORTING POLYPEPTIDE | RNA | MOUSE | SUSCEPTIBILITY | MICROBIOLOGY | GENOME | TRANSMISSION | REPLICATION | VIROLOGY | DELTA-VIRUS | LIVER | PARASITOLOGY | TRANSGENIC MICE | Antibodies, Viral - pharmacology | Hepatitis D - metabolism | Humans | Hepatocytes - pathology | Male | Host-Pathogen Interactions - drug effects | Hepatocytes - metabolism | Recombinant Fusion Proteins - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Hepatitis D - drug therapy | Viral Envelope Proteins - metabolism | Female | Hepatitis Delta Virus - drug effects | Receptor, Interferon alpha-beta - genetics | Hepatocytes - drug effects | Receptor, Interferon alpha-beta - metabolism | Specific Pathogen-Free Organisms | Immunity, Innate - drug effects | Antibodies, Monoclonal - pharmacology | Hepatitis D - virology | Hepatitis Delta Virus - physiology | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Symporters - metabolism | Mice, Knockout | Animals | Hepatitis Delta Virus - immunology | Viral Envelope Proteins - antagonists & inhibitors | Symporters - genetics | Hepatocytes - virology | Organic Anion Transporters, Sodium-Dependent - metabolism | Crosses, Genetic | Hepatitis D - pathology | Cell culture | Data analysis | Polypeptides | Pathogenesis | Science | Editing | Infections | Genomes | Mammals | Experiments | Proteins | Studies | Hepatitis | Rodents | Hepatitis delta virus
Journal Article
Hepatology, ISSN 0270-9139, 02/2017, Volume 65, Issue 2, pp. 414 - 425
Hepatitis delta virus (HDV) is the most severe form of viral hepatitis. Pegylated interferon alfa (PEG‐IFNα) is effective in only 25%‐30% of patients and is... 
SUSTAINED VIROLOGICAL RESPONSE | ALL-CAUSE MORTALITY | B-VIRUS | INTERFERON | THERAPY | RNA | ENTECAVIR TREATMENT | INFECTION | TIME | GASTROENTEROLOGY & HEPATOLOGY | FAMCICLOVIR TREATMENT | Multivariate Analysis | Liver - pathology | Follow-Up Studies | Humans | Middle Aged | Liver Cirrhosis - mortality | Male | Reference Values | Liver Neoplasms - mortality | Cause of Death | Dose-Response Relationship, Drug | Liver Neoplasms - etiology | Young Adult | Hepatitis D - drug therapy | Liver - drug effects | Time Factors | Adult | Female | Hepatitis Delta Virus - drug effects | Liver Neoplasms - pathology | Retrospective Studies | Drug Therapy, Combination | Severity of Illness Index | Liver Cirrhosis - etiology | Drug Administration Schedule | Risk Assessment | Antiviral Agents - therapeutic use | Hepatitis Delta Virus - isolation & purification | Interferon-alpha - therapeutic use | Kaplan-Meier Estimate | Logistic Models | Treatment Outcome | Chi-Square Distribution | Hepatitis D - diagnosis | Disease Progression | Analysis of Variance | Hepatitis D - mortality | Antiviral Agents - adverse effects | Adolescent | Survival Analysis | Liver Cirrhosis - pathology | Interferon-alpha - adverse effects | Germany | Cohort Studies | Hepatitis | Liver | Interferon | Syngeneic grafts | Hepatocellular carcinoma | Ribonucleic acid--RNA | Patients | Cirrhosis | α-Interferon | Allografts | Encephalopathy | Ascites | Hepatic encephalopathy | Liver transplantation
Journal Article
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 2017, Volume 64, Issue 9, pp. 1275 - 1278
Journal Article
Antiviral Research, ISSN 0166-3542, 06/2014, Volume 106, Issue 1, pp. 111 - 115
Worldwide there are approximately 240 million individuals chronically infected with the hepatitis B virus (HBV), including 15–20 million coinfected with the... 
Infection | FDA approved therapeutics | Hepatitis B virus | hNTCP | Antivirals | Hepatitis delta virus | B-VIRUS INFECTION | VIROLOGY | CHRONIC HEPATITIS-B | PHARMACOLOGY & PHARMACY | PROTEINS | ANTIVIRAL DRUGS | Ritonavir - isolation & purification | Cell Line | Antiviral Agents - pharmacology | Tetrazoles - pharmacology | Biphenyl Compounds - isolation & purification | Hepatitis Delta Virus - physiology | Humans | Organic Anion Transporters, Sodium-Dependent - antagonists & inhibitors | Ezetimibe | Azetidines - isolation & purification | Azetidines - pharmacology | Virus Internalization - drug effects | Hepatitis B virus - physiology | Hepatitis B virus - drug effects | Tetrazoles - isolation & purification | Biphenyl Compounds - pharmacology | Symporters - antagonists & inhibitors | Hepatocytes - virology | Hepatitis Delta Virus - drug effects | Ritonavir - pharmacology | Antiviral Agents - isolation & purification | Receptors, Virus - antagonists & inhibitors | Hepatocytes - drug effects | Antiviral agents | Drug approval | Ritonavir | Hepatitis Delta Virus | Antiviral Agents | Tetrazoles | Biphenyl Compounds | Virus Internalization | Life Sciences | Human health and pathology | Microbiology and Parasitology | Infectious diseases | Hepatocytes | Symporters | Azetidines | Organic Anion Transporters, Sodium-Dependent | Receptors, Virus
Journal Article
Journal Article
Current Opinion in Virology, ISSN 1879-6257, 10/2016, Volume 20, pp. 112 - 118
Hepatitis B-/D-virus co-infection causes the most severe form of viral hepatitis, frequently leading to liver cirrhosis, hepatic decompensation and consecutive... 
DRUG | B-VIRUS | ALPHA-2B | INTERFERON | LIVER-TRANSPLANTATION | ENTRY | VIROLOGY | RNA | EFFICACY | PRENYLATION INHIBITORS | IMMUNOGLOBULIN | Recurrence | Antiviral Agents - therapeutic use | Humans | Interferon-alpha - therapeutic use | Hepatitis Delta Virus - drug effects | Treatment Outcome | Hepatitis D, Chronic - drug therapy
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2011, Volume 108, Issue 38, pp. 15978 - 15983
Antiviral compounds that increase the resistance of host tissues represent an attractive class of therapeutic. Here, we show that squalamine, a compound... 
Hepatocytes | Liver | Humans | Antivirals | Viruses | Lipids | Infections | Cell membranes | Endothelial cells | P branes | Innate immunity | Hepatitis B virus | Dengue virus | Eastern equine encephalitis virus | Yellow fever virus | FEVER VIRUS-INFECTION | MURINE CYTOMEGALOVIRUS-INFECTION | hepatitis B virus | MULTIDISCIPLINARY SCIENCES | dengue virus | HAMSTER MESOCRICETUS-AURATUS | MATRIX DOMAIN | YELLOW-FEVER | GAG MEMBRANE-BINDING | VACCINE CANDIDATES | yellow fever virus | innate immunity | eastern equine encephalitis virus | EASTERN EQUINE ENCEPHALITIS | ANGIOGENESIS INHIBITOR | Hepatitis B virus - growth & development | Male | Virus Diseases - virology | Cell Membrane - chemistry | Cholestanols - chemistry | Virus Diseases - drug therapy | Antiviral Agents - chemistry | X-Ray Diffraction | Anti-Bacterial Agents - chemistry | Mesocricetus | Female | Hepatitis Delta Virus - drug effects | Molecular Structure | rac1 GTP-Binding Protein - chemistry | Cell Membrane - drug effects | Hepatocytes - drug effects | Cell Line | Virus Replication - drug effects | Antiviral Agents - pharmacology | Cricetinae | Hepatitis Delta Virus - growth & development | Cells, Cultured | Scattering, Small Angle | Muromegalovirus - growth & development | Muromegalovirus - drug effects | Cholestanols - pharmacology | Hepatitis B virus - drug effects | Animals | Hepatocytes - virology | Anti-Bacterial Agents - pharmacology | Mice | Mice, Inbred BALB C | Antiviral agents | Research | Health aspects | Biological Sciences
Journal Article